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RPS14 (ribosomal protein S14)

Identity

Alias_symbol (synonym)EMTB
S14
Other alias
HGNC (Hugo) RPS14
LocusID (NCBI) 6208
Atlas_Id 55056
Location 5q33.1  [Link to chromosome band 5q33]
Location_base_pair Starts at 150444229 and ends at 150449756 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HDLBP (2q37.3) / RPS14 (5q33.1)METTL4 (18p11.32) / RPS14 (5q33.1)RPS14 (5q33.1) / AP1G2 (14q11.2)
RPS14 (5q33.1) / RPS19 (19q13.2)RPS14 (5q33.1) / WDR6 (3p21.31)WDR26 (1q42.11) / RPS14 (5q33.1)
RPS14 5q33.1 / AP1G2 14q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  Classification of myelodysplastic syndromes 2015
del (5q) solely in Myelodysplastic syndrome


External links

Nomenclature
HGNC (Hugo)RPS14   10387
Cards
Entrez_Gene (NCBI)RPS14  6208  ribosomal protein S14
AliasesEMTB; S14
GeneCards (Weizmann)RPS14
Ensembl hg19 (Hinxton)ENSG00000164587 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164587 [Gene_View]  chr5:150444229-150449756 [Contig_View]  RPS14 [Vega]
ICGC DataPortalENSG00000164587
TCGA cBioPortalRPS14
AceView (NCBI)RPS14
Genatlas (Paris)RPS14
WikiGenes6208
SOURCE (Princeton)RPS14
Genetics Home Reference (NIH)RPS14
Genomic and cartography
GoldenPath hg38 (UCSC)RPS14  -     chr5:150444229-150449756 -  5q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPS14  -     5q33.1   [Description]    (hg19-Feb_2009)
EnsemblRPS14 - 5q33.1 [CytoView hg19]  RPS14 - 5q33.1 [CytoView hg38]
Mapping of homologs : NCBIRPS14 [Mapview hg19]  RPS14 [Mapview hg38]
OMIM130620   153550   
Gene and transcription
Genbank (Entrez)AA467888 AK312179 BC001126 BC003401 BC006784
RefSeq transcript (Entrez)NM_001025070 NM_001025071 NM_005617
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPS14
Cluster EST : UnigeneHs.744846 [ NCBI ]
CGAP (NCI)Hs.744846
Alternative Splicing GalleryENSG00000164587
Gene ExpressionRPS14 [ NCBI-GEO ]   RPS14 [ EBI - ARRAY_EXPRESS ]   RPS14 [ SEEK ]   RPS14 [ MEM ]
Gene Expression Viewer (FireBrowse)RPS14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6208
GTEX Portal (Tissue expression)RPS14
Human Protein AtlasENSG00000164587-RPS14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62263   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62263  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62263
Splice isoforms : SwissVarP62263
PhosPhoSitePlusP62263
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_S11 (PS00054)   
Domains : Interpro (EBI)Ribosomal_S11    Ribosomal_S11_CS   
Domain families : Pfam (Sanger)Ribosomal_S11 (PF00411)   
Domain families : Pfam (NCBI)pfam00411   
Conserved Domain (NCBI)RPS14
DMDM Disease mutations6208
Blocks (Seattle)RPS14
PDB (SRS)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
PDB (PDBSum)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
PDB (IMB)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
PDB (RSDB)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
Structural Biology KnowledgeBase4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
CATH (Classification of proteins structures)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
SuperfamilyP62263
Human Protein Atlas [tissue]ENSG00000164587-RPS14 [tissue]
Peptide AtlasP62263
HPRD00562
IPIIPI00026271   IPI00016636   IPI00975486   IPI00984977   
Protein Interaction databases
DIP (DOE-UCLA)P62263
IntAct (EBI)P62263
FunCoupENSG00000164587
BioGRIDRPS14
STRING (EMBL)RPS14
ZODIACRPS14
Ontologies - Pathways
QuickGOP62263
Ontology : AmiGOribosomal small subunit assembly  ribosomal small subunit assembly  negative regulation of transcription from RNA polymerase II promoter  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  RNA binding  structural constituent of ribosome  protein binding  nucleoplasm  nucleolus  mitochondrion  cytosol  focal adhesion  rRNA processing  translation  translation  translational initiation  regulation of translation  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  cytosolic small ribosomal subunit  erythrocyte differentiation  maturation of SSU-rRNA  extracellular matrix  translation regulator activity  mRNA 5'-UTR binding  extracellular exosome  small ribosomal subunit rRNA binding  
Ontology : EGO-EBIribosomal small subunit assembly  ribosomal small subunit assembly  negative regulation of transcription from RNA polymerase II promoter  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  RNA binding  structural constituent of ribosome  protein binding  nucleoplasm  nucleolus  mitochondrion  cytosol  focal adhesion  rRNA processing  translation  translation  translational initiation  regulation of translation  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  cytosolic small ribosomal subunit  erythrocyte differentiation  maturation of SSU-rRNA  extracellular matrix  translation regulator activity  mRNA 5'-UTR binding  extracellular exosome  small ribosomal subunit rRNA binding  
Pathways : KEGGRibosome   
NDEx NetworkRPS14
Atlas of Cancer Signalling NetworkRPS14
Wikipedia pathwaysRPS14
Orthology - Evolution
OrthoDB6208
GeneTree (enSembl)ENSG00000164587
Phylogenetic Trees/Animal Genes : TreeFamRPS14
HOVERGENP62263
HOGENOMP62263
Homologs : HomoloGeneRPS14
Homology/Alignments : Family Browser (UCSC)RPS14
Gene fusions - Rearrangements
Fusion : MitelmanRPS14/AP1G2 [5q33.1/14q11.2]  
Fusion: TCGA_MDACCRPS14 5q33.1 AP1G2 14q11.2 LUAD
Tumor Fusion PortalRPS14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPS14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPS14
dbVarRPS14
ClinVarRPS14
1000_GenomesRPS14 
Exome Variant ServerRPS14
ExAC (Exome Aggregation Consortium)ENSG00000164587
GNOMAD BrowserENSG00000164587
Genetic variants : HAPMAP6208
Genomic Variants (DGV)RPS14 [DGVbeta]
DECIPHERRPS14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPS14 
Mutations
ICGC Data PortalRPS14 
TCGA Data PortalRPS14 
Broad Tumor PortalRPS14
OASIS PortalRPS14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPS14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPS14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch RPS14
DgiDB (Drug Gene Interaction Database)RPS14
DoCM (Curated mutations)RPS14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPS14 (select a term)
intoGenRPS14
Cancer3DRPS14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM130620    153550   
Orphanet11750   
DisGeNETRPS14
MedgenRPS14
Genetic Testing Registry RPS14
NextProtP62263 [Medical]
TSGene6208
GENETestsRPS14
Target ValidationRPS14
Huge Navigator RPS14 [HugePedia]
snp3D : Map Gene to Disease6208
BioCentury BCIQRPS14
ClinGenRPS14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6208
Chemical/Pharm GKB GenePA34786
Clinical trialRPS14
Miscellaneous
canSAR (ICR)RPS14 (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPS14
EVEXRPS14
GoPubMedRPS14
iHOPRPS14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:33:01 CET 2017

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