Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RPS21 (ribosomal protein S21)

Identity

Alias_symbol (synonym)S21
Other aliasHLDF
HGNC (Hugo) RPS21
LocusID (NCBI) 6227
Atlas_Id 72862
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 60962121 and ends at 60963576 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANKRD52 (12q13.3) / RPS21 (20q13.33)RPS21 (20q13.33) / LRBA (4q31.3)RPS21 (20q13.33) / PIAS3 (1q21.1)
RPS21 (20q13.33) / XIST (Xq13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RPS21   10409
Cards
Entrez_Gene (NCBI)RPS21  6227  ribosomal protein S21
AliasesHLDF; S21
GeneCards (Weizmann)RPS21
Ensembl hg19 (Hinxton)ENSG00000171858 [Gene_View]  chr20:60962121-60963576 [Contig_View]  RPS21 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171858 [Gene_View]  chr20:60962121-60963576 [Contig_View]  RPS21 [Vega]
ICGC DataPortalENSG00000171858
TCGA cBioPortalRPS21
AceView (NCBI)RPS21
Genatlas (Paris)RPS21
WikiGenes6227
SOURCE (Princeton)RPS21
Genetics Home Reference (NIH)RPS21
Genomic and cartography
GoldenPath hg19 (UCSC)RPS21  -     chr20:60962121-60963576 +  20q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RPS21  -     20q13.33   [Description]    (hg38-Dec_2013)
EnsemblRPS21 - 20q13.33 [CytoView hg19]  RPS21 - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBIRPS21 [Mapview hg19]  RPS21 [Mapview hg38]
OMIM180477   
Gene and transcription
Genbank (Entrez)AV758927 BC018140 BC021990 BC027976 BC071927
RefSeq transcript (Entrez)NM_001024
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)RPS21
Cluster EST : UnigeneHs.190968 [ NCBI ]
CGAP (NCI)Hs.190968
Alternative Splicing GalleryENSG00000171858
Gene ExpressionRPS21 [ NCBI-GEO ]   RPS21 [ EBI - ARRAY_EXPRESS ]   RPS21 [ SEEK ]   RPS21 [ MEM ]
Gene Expression Viewer (FireBrowse)RPS21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6227
GTEX Portal (Tissue expression)RPS21
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63220   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP63220  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP63220
Splice isoforms : SwissVarP63220
PhosPhoSitePlusP63220
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_S21E (PS00996)   
Domains : Interpro (EBI)Ribosomal_S21e    Ribosomal_S21e_CS   
Domain families : Pfam (Sanger)Ribosomal_S21e (PF01249)   
Domain families : Pfam (NCBI)pfam01249   
Domain structure : Prodom (Prabi Lyon)Ribosomal_S21e (PD006584)   
Conserved Domain (NCBI)RPS21
DMDM Disease mutations6227
Blocks (Seattle)RPS21
PDB (SRS)4V6X   
PDB (PDBSum)4V6X   
PDB (IMB)4V6X   
PDB (RSDB)4V6X   
Structural Biology KnowledgeBase4V6X   
SCOP (Structural Classification of Proteins)4V6X   
CATH (Classification of proteins structures)4V6X   
SuperfamilyP63220
Human Protein AtlasENSG00000171858
Peptide AtlasP63220
HPRD01605
IPIIPI00017448   IPI00396086   IPI00937239   IPI00387085   IPI00387084   
Protein Interaction databases
DIP (DOE-UCLA)P63220
IntAct (EBI)P63220
FunCoupENSG00000171858
BioGRIDRPS21
STRING (EMBL)RPS21
ZODIACRPS21
Ontologies - Pathways
QuickGOP63220
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  structural constituent of ribosome  cytoplasm  cytosol  translation  translation  translation  translational initiation  translational elongation  translational termination  SRP-dependent cotranslational protein targeting to membrane  gene expression  small ribosomal subunit  viral process  viral life cycle  viral transcription  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  ribosomal small subunit biogenesis  cellular protein metabolic process  poly(A) RNA binding  protein N-terminus binding  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  structural constituent of ribosome  cytoplasm  cytosol  translation  translation  translation  translational initiation  translational elongation  translational termination  SRP-dependent cotranslational protein targeting to membrane  gene expression  small ribosomal subunit  viral process  viral life cycle  viral transcription  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  ribosomal small subunit biogenesis  cellular protein metabolic process  poly(A) RNA binding  protein N-terminus binding  
Pathways : KEGGRibosome   
NDEx NetworkRPS21
Atlas of Cancer Signalling NetworkRPS21
Wikipedia pathwaysRPS21
Orthology - Evolution
OrthoDB6227
GeneTree (enSembl)ENSG00000171858
Phylogenetic Trees/Animal Genes : TreeFamRPS21
HOVERGENP63220
HOGENOMP63220
Homologs : HomoloGeneRPS21
Homology/Alignments : Family Browser (UCSC)RPS21
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPS21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPS21
dbVarRPS21
ClinVarRPS21
1000_GenomesRPS21 
Exome Variant ServerRPS21
ExAC (Exome Aggregation Consortium)RPS21 (select the gene name)
Genetic variants : HAPMAP6227
Genomic Variants (DGV)RPS21 [DGVbeta]
DECIPHER (Syndromes)20:60962121-60963576  ENSG00000171858
CONAN: Copy Number AnalysisRPS21 
Mutations
ICGC Data PortalRPS21 
TCGA Data PortalRPS21 
Broad Tumor PortalRPS21
OASIS PortalRPS21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPS21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPS21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPS21
DgiDB (Drug Gene Interaction Database)RPS21
DoCM (Curated mutations)RPS21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPS21 (select a term)
intoGenRPS21
Cancer3DRPS21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM180477   
Orphanet
MedgenRPS21
Genetic Testing Registry RPS21
NextProtP63220 [Medical]
TSGene6227
GENETestsRPS21
Huge Navigator RPS21 [HugePedia]
snp3D : Map Gene to Disease6227
BioCentury BCIQRPS21
ClinGenRPS21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6227
Chemical/Pharm GKB GenePA34812
Clinical trialRPS21
Miscellaneous
canSAR (ICR)RPS21 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPS21
EVEXRPS21
GoPubMedRPS21
iHOPRPS21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:41:53 CET 2017

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