Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RPS4X (ribosomal protein S4, X-linked)

Identity

Alias_symbol (synonym)DXS306
CCG2
SCAR
SCR10
FLJ40595
RPS4
S4
Other alias
HGNC (Hugo) RPS4X
LocusID (NCBI) 6191
Atlas_Id 53743
Location Xq13.1  [Link to chromosome band Xq13]
Location_base_pair Starts at 72272603 and ends at 72277291 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EPHB4 (7q22.1) / RPS4X (Xq13.1)GIT2 (12q24.11) / RPS4X (Xq13.1)GNB2 (7q22.1) / RPS4X (Xq13.1)
NUP210 (3p25.1) / RPS4X (Xq13.1)RPS4X (Xq13.1) / AHSA1 (14q24.3)RPS4X (Xq13.1) / ALG10B (12q12)
RPS4X (Xq13.1) / RPS4X (Xq13.1)RPS4X (Xq13.1) / SUPT5H (19q13.2)RPS4X (Xq13.1) / ZNF24 (18q12.2)
SPTBN1 (2p16.2) / RPS4X (Xq13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RPS4X   10424
Cards
Entrez_Gene (NCBI)RPS4X  6191  ribosomal protein S4, X-linked
AliasesCCG2; DXS306; RPS4; S4; 
SCAR; SCR10
GeneCards (Weizmann)RPS4X
Ensembl hg19 (Hinxton)ENSG00000198034 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198034 [Gene_View]  chrX:72272603-72277291 [Contig_View]  RPS4X [Vega]
ICGC DataPortalENSG00000198034
TCGA cBioPortalRPS4X
AceView (NCBI)RPS4X
Genatlas (Paris)RPS4X
WikiGenes6191
SOURCE (Princeton)RPS4X
Genetics Home Reference (NIH)RPS4X
Genomic and cartography
GoldenPath hg38 (UCSC)RPS4X  -     chrX:72272603-72277291 -  Xq13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPS4X  -     Xq13.1   [Description]    (hg19-Feb_2009)
EnsemblRPS4X - Xq13.1 [CytoView hg19]  RPS4X - Xq13.1 [CytoView hg38]
Mapping of homologs : NCBIRPS4X [Mapview hg19]  RPS4X [Mapview hg38]
OMIM312760   
Gene and transcription
Genbank (Entrez)AK097914 AK222479 AK293663 AK311745 BC000472
RefSeq transcript (Entrez)NM_001007
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPS4X
Cluster EST : UnigeneHs.118076 [ NCBI ]
CGAP (NCI)Hs.118076
Alternative Splicing GalleryENSG00000198034
Gene ExpressionRPS4X [ NCBI-GEO ]   RPS4X [ EBI - ARRAY_EXPRESS ]   RPS4X [ SEEK ]   RPS4X [ MEM ]
Gene Expression Viewer (FireBrowse)RPS4X [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6191
GTEX Portal (Tissue expression)RPS4X
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62701   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62701  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62701
Splice isoforms : SwissVarP62701
PhosPhoSitePlusP62701
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_S4E (PS00528)    S4 (PS50889)   
Domains : Interpro (EBI)40S_S4_C    KOW    Ribosomal_S4e    Ribosomal_S4e_central_region    Ribosomal_S4e_N    Ribosomal_S4e_N_CS    S4_RNA-bd   
Domain families : Pfam (Sanger)40S_S4_C (PF16121)    KOW (PF00467)    Ribosomal_S4e (PF00900)    RS4NT (PF08071)    S4 (PF01479)   
Domain families : Pfam (NCBI)pfam16121    pfam00467    pfam00900    pfam08071    pfam01479   
Domain families : Smart (EMBL)S4 (SM00363)  
Domain structure : Prodom (Prabi Lyon)Ribosomal_S4e_central (PD002667)   
Conserved Domain (NCBI)RPS4X
DMDM Disease mutations6191
Blocks (Seattle)RPS4X
PDB (SRS)4UG0    4V6X    5A2Q    5T2C   
PDB (PDBSum)4UG0    4V6X    5A2Q    5T2C   
PDB (IMB)4UG0    4V6X    5A2Q    5T2C   
PDB (RSDB)4UG0    4V6X    5A2Q    5T2C   
Structural Biology KnowledgeBase4UG0    4V6X    5A2Q    5T2C   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5A2Q    5T2C   
CATH (Classification of proteins structures)4UG0    4V6X    5A2Q    5T2C   
SuperfamilyP62701
Human Protein AtlasENSG00000198034
Peptide AtlasP62701
HPRD02427
IPIIPI00217030   IPI00646114   IPI01024803   
Protein Interaction databases
DIP (DOE-UCLA)P62701
IntAct (EBI)P62701
FunCoupENSG00000198034
BioGRIDRPS4X
STRING (EMBL)RPS4X
ZODIACRPS4X
Ontologies - Pathways
QuickGOP62701
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleoplasm  cytosol  ribosome  polysome  focal adhesion  rRNA processing  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  multicellular organism development  positive regulation of cell proliferation  small ribosomal subunit  membrane  viral transcription  rRNA binding  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  intracellular ribonucleoprotein complex  extracellular matrix  cytoplasmic ribonucleoprotein granule  positive regulation of translation  extracellular exosome  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA binding  structural constituent of ribosome  protein binding  nucleoplasm  cytosol  ribosome  polysome  focal adhesion  rRNA processing  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  multicellular organism development  positive regulation of cell proliferation  small ribosomal subunit  membrane  viral transcription  rRNA binding  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  intracellular ribonucleoprotein complex  extracellular matrix  cytoplasmic ribonucleoprotein granule  positive regulation of translation  extracellular exosome  
Pathways : KEGGRibosome   
NDEx NetworkRPS4X
Atlas of Cancer Signalling NetworkRPS4X
Wikipedia pathwaysRPS4X
Orthology - Evolution
OrthoDB6191
GeneTree (enSembl)ENSG00000198034
Phylogenetic Trees/Animal Genes : TreeFamRPS4X
HOVERGENP62701
HOGENOMP62701
Homologs : HomoloGeneRPS4X
Homology/Alignments : Family Browser (UCSC)RPS4X
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPS4X [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPS4X
dbVarRPS4X
ClinVarRPS4X
1000_GenomesRPS4X 
Exome Variant ServerRPS4X
ExAC (Exome Aggregation Consortium)RPS4X (select the gene name)
Genetic variants : HAPMAP6191
Genomic Variants (DGV)RPS4X [DGVbeta]
DECIPHERRPS4X [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPS4X 
Mutations
ICGC Data PortalRPS4X 
TCGA Data PortalRPS4X 
Broad Tumor PortalRPS4X
OASIS PortalRPS4X [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPS4X  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPS4X
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch RPS4X
DgiDB (Drug Gene Interaction Database)RPS4X
DoCM (Curated mutations)RPS4X (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPS4X (select a term)
intoGenRPS4X
Cancer3DRPS4X(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM312760   
Orphanet
MedgenRPS4X
Genetic Testing Registry RPS4X
NextProtP62701 [Medical]
TSGene6191
GENETestsRPS4X
Target ValidationRPS4X
Huge Navigator RPS4X [HugePedia]
snp3D : Map Gene to Disease6191
BioCentury BCIQRPS4X
ClinGenRPS4X
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6191
Chemical/Pharm GKB GenePA34839
Clinical trialRPS4X
Miscellaneous
canSAR (ICR)RPS4X (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPS4X
EVEXRPS4X
GoPubMedRPS4X
iHOPRPS4X
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:29:32 CEST 2017

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