Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RPS8 (ribosomal protein S8)

Identity

Alias_symbol (synonym)S8
Other alias
HGNC (Hugo) RPS8
LocusID (NCBI) 6202
Atlas_Id 42170
Location 1p34.1  [Link to chromosome band 1p34]
Location_base_pair Starts at 44775574 and ends at 44778740 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DDA1 (19p13.11) / RPS8 (1p34.1)GOLGA2 (9q34.11) / RPS8 (1p34.1)LRRC4C (11p12) / RPS8 (1p34.1)
MIR6723 (1p36.33) / RPS8 (1p34.1)RPS8 (1p34.1) / AKT2 (19q13.2)RPS8 (1p34.1) / MAP3K7 (6q15)
RPS8 (1p34.1) / NISCH (3p21.1)RPS8 (1p34.1) / USP47 (11p15.3)SRP9 (1q42.12) / RPS8 (1p34.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RPS8   10441
Cards
Entrez_Gene (NCBI)RPS8  6202  ribosomal protein S8
AliasesS8
GeneCards (Weizmann)RPS8
Ensembl hg19 (Hinxton)ENSG00000142937 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142937 [Gene_View]  chr1:44775574-44778740 [Contig_View]  RPS8 [Vega]
ICGC DataPortalENSG00000142937
TCGA cBioPortalRPS8
AceView (NCBI)RPS8
Genatlas (Paris)RPS8
WikiGenes6202
SOURCE (Princeton)RPS8
Genetics Home Reference (NIH)RPS8
Genomic and cartography
GoldenPath hg38 (UCSC)RPS8  -     chr1:44775574-44778740 +  1p34.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RPS8  -     1p34.1   [Description]    (hg19-Feb_2009)
EnsemblRPS8 - 1p34.1 [CytoView hg19]  RPS8 - 1p34.1 [CytoView hg38]
Mapping of homologs : NCBIRPS8 [Mapview hg19]  RPS8 [Mapview hg38]
OMIM600357   
Gene and transcription
Genbank (Entrez)AB062401 AF116700 AK311854 BC005678 BC022070
RefSeq transcript (Entrez)NM_001012
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RPS8
Cluster EST : UnigeneHs.512675 [ NCBI ]
CGAP (NCI)Hs.512675
Alternative Splicing GalleryENSG00000142937
Gene ExpressionRPS8 [ NCBI-GEO ]   RPS8 [ EBI - ARRAY_EXPRESS ]   RPS8 [ SEEK ]   RPS8 [ MEM ]
Gene Expression Viewer (FireBrowse)RPS8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6202
GTEX Portal (Tissue expression)RPS8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62241   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62241  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62241
Splice isoforms : SwissVarP62241
PhosPhoSitePlusP62241
Domaine pattern : Prosite (Expaxy)RIBOSOMAL_S8E (PS01193)   
Domains : Interpro (EBI)Ribosomal_S8e    Ribosomal_S8e/biogenesis_NSA2    Ribosomal_S8e_CS   
Domain families : Pfam (Sanger)Ribosomal_S8e (PF01201)   
Domain families : Pfam (NCBI)pfam01201   
Conserved Domain (NCBI)RPS8
DMDM Disease mutations6202
Blocks (Seattle)RPS8
PDB (SRS)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
PDB (PDBSum)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
PDB (IMB)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
PDB (RSDB)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
Structural Biology KnowledgeBase4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
SCOP (Structural Classification of Proteins)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
CATH (Classification of proteins structures)4UG0    4V6X    5A2Q    5AJ0    5FLX    5T2C   
SuperfamilyP62241
Human Protein AtlasENSG00000142937
Peptide AtlasP62241
HPRD15969
IPIIPI00216587   IPI00815646   IPI00645201   
Protein Interaction databases
DIP (DOE-UCLA)P62241
IntAct (EBI)P62241
FunCoupENSG00000142937
BioGRIDRPS8
STRING (EMBL)RPS8
ZODIACRPS8
Ontologies - Pathways
QuickGOP62241
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  structural constituent of ribosome  nucleus  nucleoplasm  endoplasmic reticulum  cytosol  cytosol  focal adhesion  rRNA processing  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  intracellular ribonucleoprotein complex  extracellular exosome  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)  RNA binding  structural constituent of ribosome  nucleus  nucleoplasm  endoplasmic reticulum  cytosol  cytosol  focal adhesion  rRNA processing  translation  translation  translational initiation  SRP-dependent cotranslational protein targeting to membrane  membrane  viral transcription  cytosolic small ribosomal subunit  cytosolic small ribosomal subunit  intracellular ribonucleoprotein complex  extracellular exosome  
Pathways : KEGGRibosome   
NDEx NetworkRPS8
Atlas of Cancer Signalling NetworkRPS8
Wikipedia pathwaysRPS8
Orthology - Evolution
OrthoDB6202
GeneTree (enSembl)ENSG00000142937
Phylogenetic Trees/Animal Genes : TreeFamRPS8
HOVERGENP62241
HOGENOMP62241
Homologs : HomoloGeneRPS8
Homology/Alignments : Family Browser (UCSC)RPS8
Gene fusions - Rearrangements
Fusion Cancer (Beijing)MIR6723 [RPS8]  -  1p34.1 [FUSC000957]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRPS8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RPS8
dbVarRPS8
ClinVarRPS8
1000_GenomesRPS8 
Exome Variant ServerRPS8
ExAC (Exome Aggregation Consortium)RPS8 (select the gene name)
Genetic variants : HAPMAP6202
Genomic Variants (DGV)RPS8 [DGVbeta]
DECIPHERRPS8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRPS8 
Mutations
ICGC Data PortalRPS8 
TCGA Data PortalRPS8 
Broad Tumor PortalRPS8
OASIS PortalRPS8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRPS8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRPS8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RPS8
DgiDB (Drug Gene Interaction Database)RPS8
DoCM (Curated mutations)RPS8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RPS8 (select a term)
intoGenRPS8
Cancer3DRPS8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600357   
Orphanet
MedgenRPS8
Genetic Testing Registry RPS8
NextProtP62241 [Medical]
TSGene6202
GENETestsRPS8
Target ValidationRPS8
Huge Navigator RPS8 [HugePedia]
snp3D : Map Gene to Disease6202
BioCentury BCIQRPS8
ClinGenRPS8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6202
Chemical/Pharm GKB GenePA34856
Clinical trialRPS8
Miscellaneous
canSAR (ICR)RPS8 (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRPS8
EVEXRPS8
GoPubMedRPS8
iHOPRPS8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:54:00 CEST 2017

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