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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

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RRAS2 (related RAS viral (r-ras) oncogene homolog 2)

Identity

Other namesTC21
HGNC (Hugo) RRAS2
LocusID (NCBI) 22800
Location 11p15.2
Location_base_pair Starts at 14299466 and ends at 14380073 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)RRAS2   17271
Cards
Entrez_Gene (NCBI)RRAS2  22800  related RAS viral (r-ras) oncogene homolog 2
GeneCards (Weizmann)RRAS2
Ensembl hg19 (Hinxton)ENSG00000133818 [Gene_View]  chr11:14299466-14380073 [Contig_View]  RRAS2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000133818 [Gene_View]  chr11:14299466-14380073 [Contig_View]  RRAS2 [Vega]
ICGC DataPortalENSG00000133818
cBioPortalRRAS2
AceView (NCBI)RRAS2
Genatlas (Paris)RRAS2
WikiGenes22800
SOURCE (Princeton)RRAS2
Genomic and cartography
GoldenPath hg19 (UCSC)RRAS2  -     chr11:14299466-14380073 -  11p15.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RRAS2  -     11p15.2   [Description]    (hg38-Dec_2013)
EnsemblRRAS2 - 11p15.2 [CytoView hg19]  RRAS2 - 11p15.2 [CytoView hg38]
Mapping of homologs : NCBIRRAS2 [Mapview hg19]  RRAS2 [Mapview hg38]
OMIM600098   
Gene and transcription
Genbank (Entrez)AA873016 AF493924 AK299606 AK300103 AK302033
RefSeq transcript (Entrez)NM_001102669 NM_001177314 NM_001177315 NM_012250
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_017058 NT_009237 NW_001838022 NW_004929378
Consensus coding sequences : CCDS (NCBI)RRAS2
Cluster EST : UnigeneHs.712835 [ NCBI ]
CGAP (NCI)Hs.712835
Alternative Splicing : Fast-db (Paris)GSHG0005609
Alternative Splicing GalleryENSG00000133818
Gene ExpressionRRAS2 [ NCBI-GEO ]     RRAS2 [ SEEK ]   RRAS2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62070 (Uniprot)
NextProtP62070  [Medical]
With graphics : InterProP62070
Splice isoforms : SwissVarP62070 (Swissvar)
Domaine pattern : Prosite (Expaxy)RAS (PS51421)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase    Small_GTPase_Ras   
Related proteins : CluSTrP62070
Domain families : Pfam (Sanger)Ras (PF00071)   
Domain families : Pfam (NCBI)pfam00071   
Domain families : Smart (EMBL)RAS (SM00173)  
DMDM Disease mutations22800
Blocks (Seattle)P62070
PDB (SRS)2ERY   
PDB (PDBSum)2ERY   
PDB (IMB)2ERY   
PDB (RSDB)2ERY   
Human Protein AtlasENSG00000133818
Peptide AtlasP62070
HPRD02518
IPIIPI01011983   IPI00012512   IPI00956295   IPI00856004   IPI00983298   IPI00982471   IPI00985118   IPI00981826   
Protein Interaction databases
DIP (DOE-UCLA)P62070
IntAct (EBI)P62070
FunCoupENSG00000133818
BioGRIDRRAS2
IntegromeDBRRAS2
STRING (EMBL)RRAS2
Ontologies - Pathways
QuickGOP62070
Ontology : AmiGOosteoblast differentiation  GTPase activity  protein binding  GTP binding  endoplasmic reticulum  plasma membrane  GTP catabolic process  Ras protein signal transduction  membrane  positive regulation of cell migration  extracellular vesicular exosome  
Ontology : EGO-EBIosteoblast differentiation  GTPase activity  protein binding  GTP binding  endoplasmic reticulum  plasma membrane  GTP catabolic process  Ras protein signal transduction  membrane  positive regulation of cell migration  extracellular vesicular exosome  
Pathways : KEGGMAPK signaling pathway    Ras signaling pathway    Tight junction    Regulation of actin cytoskeleton    HTLV-I infection    Proteoglycans in cancer   
Protein Interaction DatabaseRRAS2
DoCM (Curated mutations)RRAS2
Wikipedia pathwaysRRAS2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerRRAS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RRAS2
dbVarRRAS2
ClinVarRRAS2
1000_GenomesRRAS2 
Exome Variant ServerRRAS2
SNP (GeneSNP Utah)RRAS2
SNP : HGBaseRRAS2
Genetic variants : HAPMAPRRAS2
Genomic Variants (DGV)RRAS2 [DGVbeta]
Mutations
ICGC Data PortalENSG00000133818 
Somatic Mutations in Cancer : COSMICRRAS2 
CONAN: Copy Number AnalysisRRAS2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)11:14299466-14380073
Mutations and Diseases : HGMDRRAS2
OMIM600098   
MedgenRRAS2
NextProtP62070 [Medical]
GENETestsRRAS2
Disease Genetic AssociationRRAS2
Huge Navigator RRAS2 [HugePedia]  RRAS2 [HugeCancerGEM]
snp3D : Map Gene to Disease22800
DGIdb (Drug Gene Interaction db)RRAS2
General knowledge
Homologs : HomoloGeneRRAS2
Homology/Alignments : Family Browser (UCSC)RRAS2
Phylogenetic Trees/Animal Genes : TreeFamRRAS2
Chemical/Protein Interactions : CTD22800
Chemical/Pharm GKB GenePA34862
Clinical trialRRAS2
Cancer Resource (Charite)ENSG00000133818
Other databases
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
CoreMineRRAS2
GoPubMedRRAS2
iHOPRRAS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 18:24:33 CET 2015

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