RRM1 (ribonucleotide reductase M1)

Identity

Other names	R1
	RIR1
	RR1
HGNC	RRM1
Location	11p15.5
Location_base_pair	Starts at 4072500 and ends at 4116682 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	RRM1   10451
Entrez_Gene	RRM1  6240  ribonucleotide reductase M1
	Cards
GeneCards	RRM1
Ensembl	ENSG00000167325 [Gene_View]  RRM1 [Vega]
Genatlas	RRM1
	Genomic and cartography
GoldenPath	RRM1  -  11p15.5   chr11:4072500-4116682 +  11p15.4   [Description]    (hg18-March_2006)
Ensembl	RRM1 - 11p15.4 [CytoView]
NCBI	Mapview
OMIM	180410 Disease map [OMIM]
HomoloGene	RRM1
	Gene and transcription
Genbank	AK222786 [ ENTREZ ]
Genbank	AK297988 [ ENTREZ ]
Genbank	AK299629 [ ENTREZ ]
Genbank	AK301922 [ ENTREZ ]
Genbank	AK303394 [ ENTREZ ]
RefSeq	NM_001033 [ SRS ]    NM_001033 [ ENTREZ ]
RefSeq	AC_000054 [ SRS ]    AC_000054 [ ENTREZ ]
RefSeq	AC_000143 [ SRS ]    AC_000143 [ ENTREZ ]
RefSeq	NC_000011 [ SRS ]    NC_000011 [ ENTREZ ]
RefSeq	NT_009237 [ SRS ]    NT_009237 [ ENTREZ ]
RefSeq	NW_001838018 [ SRS ]    NW_001838018 [ ENTREZ ]
RefSeq	NW_924962 [ SRS ]    NW_924962 [ ENTREZ ]
CCDS	RRM1 CCDS - NCBI
AceView	RRM1 AceView - NCBI
Unigene	Hs.558393 [ SRS ]    Hs.558393 [ NCBI ]
Fast-db	1534 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P23921 [ SRS]    P23921 [ EXPASY ]     P23921 [ INTERPRO ]     P23921 [ UNIPROT ] P23921 [ VarSplice FASTA ]
Prosite	PS51161 ATP_CONE [ SRS ]    PS51161 ATP_CONE [ Expasy ]
Prosite	PS00089 RIBORED_LARGE [ SRS ]    PS00089 RIBORED_LARGE [ Expasy ]
Interpro	IPR005144 ATP-cone [ SRS ]    IPR005144 ATP-cone [ EBI ]
Interpro	IPR013346 NrdE_NrdA [ SRS ]    IPR013346 NrdE_NrdA [ EBI ]
Interpro	IPR000788 Ribncl_red_lg_C [ SRS ]    IPR000788 Ribncl_red_lg_C [ EBI ]
Interpro	IPR013509 Ribncl_red_lg_N [ SRS ]    IPR013509 Ribncl_red_lg_N [ EBI ]
CluSTr	P23921
Pfam	PF03477 ATP-cone [ SRS ]    PF03477 ATP-cone [ Sanger ]    pfam03477 [ NCBI-CDD ]
Pfam	PF02867 Ribonuc_red_lgC [ SRS ]    PF02867 Ribonuc_red_lgC [ Sanger ]    pfam02867 [ NCBI-CDD ]
Pfam	PF00317 Ribonuc_red_lgN [ SRS ]    PF00317 Ribonuc_red_lgN [ Sanger ]    pfam00317 [ NCBI-CDD ]
Blocks	P23921
HPRD	01588
	Protein Interaction databases
DIP	P23921
IntAct	P23921
	Polymorphism : SNP, mutations, diseases
OMIM	180410    [ map ]
GENETests	180410
SNP	RRM1 [dbSNP-NCBI]
SNP	NM_001033 [SNP-NCI]
SNP	RRM1 [GeneSNPs - Utah]  RRM1] [HGBASE - SRS]
HAPMAP	RRM1 [HAPMAP]
COSMIC	RRM1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	RRM1
Genetic Association	RRM1
CDC HuGE	RRM1
	General knowledge
Family Browser	RRM1 [UCSC Family Browser]
SOURCE	NM_001033
SMD	Hs.558393
SAGE	Hs.558393
Enzyme	1.17.4.1 [ Enzyme-Expasy ]   1.17.4.1 [ Enzyme-SRS ]   1.17.4.1 [ IntEnz-EBI ]   1.17.4.1 [ BRENDA ]   1.17.4.1 [ KEGG ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	ribonucleoside-diphosphate reductase activity [Amigo]  ribonucleoside-diphosphate reductase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	ribonucleoside-diphosphate reductase complex [Amigo]  ribonucleoside-diphosphate reductase complex
GO	DNA replication [Amigo]  DNA replication
GO	oxidoreductase activity [Amigo]  oxidoreductase activity
GO	oxidation reduction [Amigo]  oxidation reduction
KEGG	Purine metabolism
KEGG	Pyrimidine metabolism
PubGene	RRM1
TreeFam	RRM1
CTD	6240 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	RRM1 Related clones (RZPD - Berlin)
	PubMed
PubMed	41 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu Nov 27 14:10:04 2008