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RRN3 (RRN3 homolog, RNA polymerase I transcription factor)

Identity

Alias (NCBI)A-270G1.2
TIFIA
HGNC (Hugo) RRN3
HGNC Alias symbDKFZp566E104
TIF-IA
HGNC Alias nametranscription initiation factor IA
HGNC Previous nameRRN3 RNA polymerase I transcription factor homolog (yeast)
 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
LocusID (NCBI) 54700
Atlas_Id 50094
Location 16p13.11  [Link to chromosome band 16p13]
Location_base_pair Starts at 15060033 and ends at 15094272 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PARN (16p13.12) / RRN3 (16p13.11)PARN 16p13.12 / RRN3 16p13.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RRN3   30346
Cards
Entrez_Gene (NCBI)RRN3    RRN3 homolog, RNA polymerase I transcription factor
AliasesA-270G1.2; TIFIA
GeneCards (Weizmann)RRN3
Ensembl hg19 (Hinxton)ENSG00000085721 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000085721 [Gene_View]  ENSG00000085721 [Sequence]  chr16:15060033-15094272 [Contig_View]  RRN3 [Vega]
ICGC DataPortalENSG00000085721
TCGA cBioPortalRRN3
AceView (NCBI)RRN3
Genatlas (Paris)RRN3
SOURCE (Princeton)RRN3
Genetics Home Reference (NIH)RRN3
Genomic and cartography
GoldenPath hg38 (UCSC)RRN3  -     chr16:15060033-15094272 -  16p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RRN3  -     16p13.11   [Description]    (hg19-Feb_2009)
GoldenPathRRN3 - 16p13.11 [CytoView hg19]  RRN3 - 16p13.11 [CytoView hg38]
ImmunoBaseENSG00000085721
Genome Data Viewer NCBIRRN3 [Mapview hg19]  
OMIM605121   
Gene and transcription
Genbank (Entrez)AF227156 AJ272050 AK225662 AK295486 AK300253
RefSeq transcript (Entrez)NM_001301064 NM_018427
Consensus coding sequences : CCDS (NCBI)RRN3
Gene ExpressionRRN3 [ NCBI-GEO ]   RRN3 [ EBI - ARRAY_EXPRESS ]   RRN3 [ SEEK ]   RRN3 [ MEM ]
Gene Expression Viewer (FireBrowse)RRN3 [ Firebrowse - Broad ]
GenevisibleExpression of RRN3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54700
GTEX Portal (Tissue expression)RRN3
Human Protein AtlasENSG00000085721-RRN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYV6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYV6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYV6
PhosPhoSitePlusQ9NYV6
Domains : Interpro (EBI)RNA_pol_I_trans_ini_fac_RRN3   
Domain families : Pfam (Sanger)RRN3 (PF05327)   
Domain families : Pfam (NCBI)pfam05327   
Conserved Domain (NCBI)RRN3
SuperfamilyQ9NYV6
AlphaFold pdb e-kbQ9NYV6   
Human Protein Atlas [tissue]ENSG00000085721-RRN3 [tissue]
HPRD12004
Protein Interaction databases
DIP (DOE-UCLA)Q9NYV6
IntAct (EBI)Q9NYV6
BioGRIDRRN3
STRING (EMBL)RRN3
ZODIACRRN3
Ontologies - Pathways
QuickGOQ9NYV6
Ontology : AmiGORNA polymerase I core binding  RNA polymerase I core promoter sequence-specific DNA binding  RNA polymerase I general transcription initiation factor activity  RNA polymerase I preinitiation complex assembly  nucleus  nucleoplasm  nucleolus  transcription initiation from RNA polymerase I promoter  transcription initiation from RNA polymerase I promoter  positive regulation of neuron projection development  
Ontology : EGO-EBIRNA polymerase I core binding  RNA polymerase I core promoter sequence-specific DNA binding  RNA polymerase I general transcription initiation factor activity  RNA polymerase I preinitiation complex assembly  nucleus  nucleoplasm  nucleolus  transcription initiation from RNA polymerase I promoter  transcription initiation from RNA polymerase I promoter  positive regulation of neuron projection development  
NDEx NetworkRRN3
Atlas of Cancer Signalling NetworkRRN3
Wikipedia pathwaysRRN3
Orthology - Evolution
OrthoDB54700
GeneTree (enSembl)ENSG00000085721
Phylogenetic Trees/Animal Genes : TreeFamRRN3
Homologs : HomoloGeneRRN3
Homology/Alignments : Family Browser (UCSC)RRN3
Gene fusions - Rearrangements
Fusion : MitelmanPARN/RRN3 [16p13.12/16p13.11]  
Fusion : QuiverRRN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRRN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RRN3
dbVarRRN3
ClinVarRRN3
MonarchRRN3
1000_GenomesRRN3 
Exome Variant ServerRRN3
GNOMAD BrowserENSG00000085721
Varsome BrowserRRN3
ACMGRRN3 variants
VarityQ9NYV6
Genomic Variants (DGV)RRN3 [DGVbeta]
DECIPHERRRN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRRN3 
Mutations
ICGC Data PortalRRN3 
TCGA Data PortalRRN3 
Broad Tumor PortalRRN3
OASIS PortalRRN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRRN3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRRN3
Mutations and Diseases : HGMDRRN3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRRN3
DgiDB (Drug Gene Interaction Database)RRN3
DoCM (Curated mutations)RRN3
CIViC (Clinical Interpretations of Variants in Cancer)RRN3
Cancer3DRRN3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605121   
Orphanet
DisGeNETRRN3
MedgenRRN3
Genetic Testing Registry RRN3
NextProtQ9NYV6 [Medical]
GENETestsRRN3
Target ValidationRRN3
Huge Navigator RRN3 [HugePedia]
ClinGenRRN3
Clinical trials, drugs, therapy
MyCancerGenomeRRN3
Protein Interactions : CTDRRN3
Pharm GKB GenePA134878601
PharosQ9NYV6
Clinical trialRRN3
Miscellaneous
canSAR (ICR)RRN3
HarmonizomeRRN3
DataMed IndexRRN3
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRRN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:29:43 CEST 2021

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