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RRP12 (ribosomal RNA processing 12 homolog)

Identity

Alias_namesKIAA0690
KIAA0690
ribosomal RNA processing 12 homolog (S. cerevisiae)
Other alias
HGNC (Hugo) RRP12
LocusID (NCBI) 23223
Atlas_Id 56846
Location 10q24.1  [Link to chromosome band 10q24]
Location_base_pair Starts at 97356701 and ends at 97401340 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARHGAP19 (10q24.1) / RRP12 (10q24.1)EFCAB10 (7q22.3) / RRP12 (10q24.1)RRP12 (10q24.1) / ARRB1 (11q13.4)
RRP12 (10q24.1) / CRTAC1 (10q24.2)RRP12 (10q24.1) / EXOSC1 (10q24.1)RRP12 (10q24.1) / LOC100507412 (-)
RRP12 (10q24.1) / PIGR (1q32.1)RRP12 (10q24.1) / PTMA (2q37.1)RRP12 (10q24.1) / RRP12 (10q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  ARHGAP19/RRP12 (10q24)
RRP12/CRTAC1 (10q24)
RRP12/EXOSC1 (10q24)


External links

Nomenclature
HGNC (Hugo)RRP12   29100
Cards
Entrez_Gene (NCBI)RRP12  23223  ribosomal RNA processing 12 homolog
AliasesKIAA0690
GeneCards (Weizmann)RRP12
Ensembl hg19 (Hinxton)ENSG00000052749 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000052749 [Gene_View]  ENSG00000052749 [Sequence]  chr10:97356701-97401340 [Contig_View]  RRP12 [Vega]
ICGC DataPortalENSG00000052749
TCGA cBioPortalRRP12
AceView (NCBI)RRP12
Genatlas (Paris)RRP12
WikiGenes23223
SOURCE (Princeton)RRP12
Genetics Home Reference (NIH)RRP12
Genomic and cartography
GoldenPath hg38 (UCSC)RRP12  -     chr10:97356701-97401340 -  10q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RRP12  -     10q24.1   [Description]    (hg19-Feb_2009)
GoldenPathRRP12 - 10q24.1 [CytoView hg19]  RRP12 - 10q24.1 [CytoView hg38]
Genome Data Viewer NCBIRRP12 [Mapview hg19]  
OMIM617723   
Gene and transcription
Genbank (Entrez)AB014590 AK000238 AK021460 AK022496 AK056614
RefSeq transcript (Entrez)NM_001145114 NM_001284337 NM_015179
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RRP12
Alternative Splicing GalleryENSG00000052749
Gene ExpressionRRP12 [ NCBI-GEO ]   RRP12 [ EBI - ARRAY_EXPRESS ]   RRP12 [ SEEK ]   RRP12 [ MEM ]
Gene Expression Viewer (FireBrowse)RRP12 [ Firebrowse - Broad ]
GenevisibleExpression of RRP12 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23223
GTEX Portal (Tissue expression)RRP12
Human Protein AtlasENSG00000052749-RRP12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JTH9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JTH9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JTH9
Splice isoforms : SwissVarQ5JTH9
PhosPhoSitePlusQ5JTH9
Domains : Interpro (EBI)ARM-type_fold    Uncharacterised_NUC173   
Domain families : Pfam (Sanger)NUC173 (PF08161)   
Domain families : Pfam (NCBI)pfam08161   
Conserved Domain (NCBI)RRP12
DMDM Disease mutations23223
SuperfamilyQ5JTH9
Human Protein Atlas [tissue]ENSG00000052749-RRP12 [tissue]
Peptide AtlasQ5JTH9
IPIIPI00101186   IPI00940901   IPI01011408   IPI00294794   
Protein Interaction databases
DIP (DOE-UCLA)Q5JTH9
IntAct (EBI)Q5JTH9
FunCoupENSG00000052749
BioGRIDRRP12
STRING (EMBL)RRP12
ZODIACRRP12
Ontologies - Pathways
QuickGOQ5JTH9
Ontology : AmiGORNA binding  nucleolus  nucleolus  cytosol  plasma membrane  rRNA processing  integral component of membrane  nuclear membrane  intracellular membrane-bounded organelle  
Ontology : EGO-EBIRNA binding  nucleolus  nucleolus  cytosol  plasma membrane  rRNA processing  integral component of membrane  nuclear membrane  intracellular membrane-bounded organelle  
NDEx NetworkRRP12
Atlas of Cancer Signalling NetworkRRP12
Wikipedia pathwaysRRP12
Orthology - Evolution
OrthoDB23223
GeneTree (enSembl)ENSG00000052749
Phylogenetic Trees/Animal Genes : TreeFamRRP12
HOGENOMQ5JTH9
Homologs : HomoloGeneRRP12
Homology/Alignments : Family Browser (UCSC)RRP12
Gene fusions - Rearrangements
Fusion : QuiverRRP12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRRP12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RRP12
dbVarRRP12
ClinVarRRP12
1000_GenomesRRP12 
Exome Variant ServerRRP12
GNOMAD BrowserENSG00000052749
Varsome BrowserRRP12
Genetic variants : HAPMAP23223
Genomic Variants (DGV)RRP12 [DGVbeta]
DECIPHERRRP12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRRP12 
Mutations
ICGC Data PortalRRP12 
TCGA Data PortalRRP12 
Broad Tumor PortalRRP12
OASIS PortalRRP12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRRP12  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRRP12
Mutations and Diseases : HGMDRRP12
BioMutaselect RRP12
DgiDB (Drug Gene Interaction Database)RRP12
DoCM (Curated mutations)RRP12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RRP12 (select a term)
intoGenRRP12
Cancer3DRRP12 (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617723   
Orphanet
DisGeNETRRP12
MedgenRRP12
Genetic Testing Registry RRP12
NextProtQ5JTH9 [Medical]
TSGene23223
GENETestsRRP12
Open Targets GeneticsENSG00000052749  [validation]
snp3D : Map Gene to Disease23223
BioCentury BCIQRRP12
ClinGenRRP12
Clinical trials, drugs, therapy
Protein Interactions : CTD23223
Pharm GKB GenePA162402122
Clinical trialRRP12
Miscellaneous
canSAR (ICR)RRP12 (select the gene name)
HarmonizomeRRP12
DataMed IndexRRP12
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRRP12
EVEXRRP12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jul 11 20:09:49 CEST 2020

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