Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase)

Identity

Alias_namesC22orf28
chromosome 22 open reading frame 28
Alias_symbol (synonym)HSPC117
FAAP
Other aliasDJ149A16.6
HGNC (Hugo) RTCB
LocusID (NCBI) 51493
Atlas_Id 72922
Location 22q12.3  [Link to chromosome band 22q12]
Location_base_pair Starts at 32387575 and ends at 32412287 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CRTAP (3p22.3) / RTCB (22q12.3)RTCB (22q12.3) / FAM83F (22q13.1)RTCB (22q12.3) / RTCB (22q12.3)
XPNPEP3 (22q13.2) / RTCB (22q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RTCB   26935
Cards
Entrez_Gene (NCBI)RTCB  51493  RNA 2',3'-cyclic phosphate and 5'-OH ligase
AliasesC22orf28; DJ149A16.6; FAAP; HSPC117
GeneCards (Weizmann)RTCB
Ensembl hg19 (Hinxton)ENSG00000100220 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100220 [Gene_View]  chr22:32387575-32412287 [Contig_View]  RTCB [Vega]
ICGC DataPortalENSG00000100220
TCGA cBioPortalRTCB
AceView (NCBI)RTCB
Genatlas (Paris)RTCB
WikiGenes51493
SOURCE (Princeton)RTCB
Genetics Home Reference (NIH)RTCB
Genomic and cartography
GoldenPath hg38 (UCSC)RTCB  -     chr22:32387575-32412287 -  22q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RTCB  -     22q12.3   [Description]    (hg19-Feb_2009)
EnsemblRTCB - 22q12.3 [CytoView hg19]  RTCB - 22q12.3 [CytoView hg38]
Mapping of homologs : NCBIRTCB [Mapview hg19]  RTCB [Mapview hg38]
OMIM613901   
Gene and transcription
Genbank (Entrez)AF155658 AF161466 AK297826 AK297908 AK301945
RefSeq transcript (Entrez)NM_014306
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RTCB
Cluster EST : UnigeneHs.474643 [ NCBI ]
CGAP (NCI)Hs.474643
Alternative Splicing GalleryENSG00000100220
Gene ExpressionRTCB [ NCBI-GEO ]   RTCB [ EBI - ARRAY_EXPRESS ]   RTCB [ SEEK ]   RTCB [ MEM ]
Gene Expression Viewer (FireBrowse)RTCB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51493
GTEX Portal (Tissue expression)RTCB
Human Protein AtlasENSG00000100220-RTCB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3I0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3I0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3I0
Splice isoforms : SwissVarQ9Y3I0
PhosPhoSitePlusQ9Y3I0
Domaine pattern : Prosite (Expaxy)UPF0027 (PS01288)   
Domains : Interpro (EBI)RtcB    RtcB_euk   
Domain families : Pfam (Sanger)RtcB (PF01139)   
Domain families : Pfam (NCBI)pfam01139   
Conserved Domain (NCBI)RTCB
DMDM Disease mutations51493
Blocks (Seattle)RTCB
SuperfamilyQ9Y3I0
Human Protein Atlas [tissue]ENSG00000100220-RTCB [tissue]
Peptide AtlasQ9Y3I0
HPRD13695
IPIIPI00550689   IPI00909218   IPI00910259   IPI00910144   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3I0
IntAct (EBI)Q9Y3I0
FunCoupENSG00000100220
BioGRIDRTCB
STRING (EMBL)RTCB
ZODIACRTCB
Ontologies - Pathways
QuickGOQ9Y3I0
Ontology : AmiGOin utero embryonic development  placenta development  RNA binding  RNA ligase (ATP) activity  RNA ligase (ATP) activity  protein binding  ATP binding  nucleus  nuclear envelope  nucleoplasm  nucleoplasm  cytoplasm  endoplasmic reticulum membrane  cytosol  tRNA splicing, via endonucleolytic cleavage and ligation  tRNA splicing, via endonucleolytic cleavage and ligation  vinculin binding  intracellular membrane-bounded organelle  metal ion binding  tRNA-splicing ligase complex  
Ontology : EGO-EBIin utero embryonic development  placenta development  RNA binding  RNA ligase (ATP) activity  RNA ligase (ATP) activity  protein binding  ATP binding  nucleus  nuclear envelope  nucleoplasm  nucleoplasm  cytoplasm  endoplasmic reticulum membrane  cytosol  tRNA splicing, via endonucleolytic cleavage and ligation  tRNA splicing, via endonucleolytic cleavage and ligation  vinculin binding  intracellular membrane-bounded organelle  metal ion binding  tRNA-splicing ligase complex  
NDEx NetworkRTCB
Atlas of Cancer Signalling NetworkRTCB
Wikipedia pathwaysRTCB
Orthology - Evolution
OrthoDB51493
GeneTree (enSembl)ENSG00000100220
Phylogenetic Trees/Animal Genes : TreeFamRTCB
HOVERGENQ9Y3I0
HOGENOMQ9Y3I0
Homologs : HomoloGeneRTCB
Homology/Alignments : Family Browser (UCSC)RTCB
Gene fusions - Rearrangements
Tumor Fusion PortalRTCB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRTCB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RTCB
dbVarRTCB
ClinVarRTCB
1000_GenomesRTCB 
Exome Variant ServerRTCB
ExAC (Exome Aggregation Consortium)ENSG00000100220
GNOMAD BrowserENSG00000100220
Genetic variants : HAPMAP51493
Genomic Variants (DGV)RTCB [DGVbeta]
DECIPHERRTCB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRTCB 
Mutations
ICGC Data PortalRTCB 
TCGA Data PortalRTCB 
Broad Tumor PortalRTCB
OASIS PortalRTCB [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDRTCB
BioMutasearch RTCB
DgiDB (Drug Gene Interaction Database)RTCB
DoCM (Curated mutations)RTCB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RTCB (select a term)
intoGenRTCB
Cancer3DRTCB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613901   
Orphanet
DisGeNETRTCB
MedgenRTCB
Genetic Testing Registry RTCB
NextProtQ9Y3I0 [Medical]
TSGene51493
GENETestsRTCB
Target ValidationRTCB
Huge Navigator RTCB [HugePedia]
snp3D : Map Gene to Disease51493
BioCentury BCIQRTCB
ClinGenRTCB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51493
Chemical/Pharm GKB GenePA145149387
Clinical trialRTCB
Miscellaneous
canSAR (ICR)RTCB (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRTCB
EVEXRTCB
GoPubMedRTCB
iHOPRTCB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:44:17 CET 2017

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