Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RTN1 (reticulon 1)

Identity

Alias_namesNSP
neuroendocrine-specific protein
Other alias
HGNC (Hugo) RTN1
LocusID (NCBI) 6252
Atlas_Id 42181
Location 14q23.1  [Link to chromosome band 14q23]
Location_base_pair Starts at 59595976 and ends at 59870839 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RTN1 (14q23.1) / DLL1 (6q27)RTN1 (14q23.1) / DPYSL2 (8p21.2)SAMD12 (8q24.12) / RTN1 (14q23.1)
SYNE2 (14q23.2) / RTN1 (14q23.1)YME1L1 (10p12.1) / RTN1 (14q23.1)SAMD12 8q24.12 / RTN1 14q23.1
SYNE2 14q23.2 / RTN1 14q23.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RTN1   10467
Cards
Entrez_Gene (NCBI)RTN1  6252  reticulon 1
AliasesNSP
GeneCards (Weizmann)RTN1
Ensembl hg19 (Hinxton)ENSG00000139970 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139970 [Gene_View]  chr14:59595976-59870839 [Contig_View]  RTN1 [Vega]
ICGC DataPortalENSG00000139970
TCGA cBioPortalRTN1
AceView (NCBI)RTN1
Genatlas (Paris)RTN1
WikiGenes6252
SOURCE (Princeton)RTN1
Genetics Home Reference (NIH)RTN1
Genomic and cartography
GoldenPath hg38 (UCSC)RTN1  -     chr14:59595976-59870839 -  14q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RTN1  -     14q23.1   [Description]    (hg19-Feb_2009)
EnsemblRTN1 - 14q23.1 [CytoView hg19]  RTN1 - 14q23.1 [CytoView hg38]
Mapping of homologs : NCBIRTN1 [Mapview hg19]  RTN1 [Mapview hg38]
OMIM600865   
Gene and transcription
Genbank (Entrez)AK128113 AK290534 AK297492 BC000314 BC003003
RefSeq transcript (Entrez)NM_001243115 NM_021136 NM_206852 NM_206857
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RTN1
Cluster EST : UnigeneHs.368626 [ NCBI ]
CGAP (NCI)Hs.368626
Alternative Splicing GalleryENSG00000139970
Gene ExpressionRTN1 [ NCBI-GEO ]   RTN1 [ EBI - ARRAY_EXPRESS ]   RTN1 [ SEEK ]   RTN1 [ MEM ]
Gene Expression Viewer (FireBrowse)RTN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6252
GTEX Portal (Tissue expression)RTN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16799   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16799  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16799
Splice isoforms : SwissVarQ16799
PhosPhoSitePlusQ16799
Domaine pattern : Prosite (Expaxy)RETICULON (PS50845)   
Domains : Interpro (EBI)Reticulon   
Domain families : Pfam (Sanger)Reticulon (PF02453)   
Domain families : Pfam (NCBI)pfam02453   
Conserved Domain (NCBI)RTN1
DMDM Disease mutations6252
Blocks (Seattle)RTN1
SuperfamilyQ16799
Human Protein AtlasENSG00000139970
Peptide AtlasQ16799
HPRD02921
IPIIPI00003971   IPI00219812   IPI00219813   IPI01015860   IPI00794113   
Protein Interaction databases
DIP (DOE-UCLA)Q16799
IntAct (EBI)Q16799
FunCoupENSG00000139970
BioGRIDRTN1
STRING (EMBL)RTN1
ZODIACRTN1
Ontologies - Pathways
QuickGOQ16799
Ontology : AmiGOprotein binding  endoplasmic reticulum  integral component of endoplasmic reticulum membrane  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  integral component of endoplasmic reticulum membrane  
NDEx NetworkRTN1
Atlas of Cancer Signalling NetworkRTN1
Wikipedia pathwaysRTN1
Orthology - Evolution
OrthoDB6252
GeneTree (enSembl)ENSG00000139970
Phylogenetic Trees/Animal Genes : TreeFamRTN1
HOVERGENQ16799
HOGENOMQ16799
Homologs : HomoloGeneRTN1
Homology/Alignments : Family Browser (UCSC)RTN1
Gene fusions - Rearrangements
Fusion : MitelmanSAMD12/RTN1 [8q24.12/14q23.1]  [t(8;14)(q24;q23)]  
Fusion : MitelmanSYNE2/RTN1 [14q23.2/14q23.1]  [t(14;14)(q23;q23)]  
Fusion: TCGASAMD12 8q24.12 RTN1 14q23.1 LUSC
Fusion: TCGASYNE2 14q23.2 RTN1 14q23.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRTN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RTN1
dbVarRTN1
ClinVarRTN1
1000_GenomesRTN1 
Exome Variant ServerRTN1
ExAC (Exome Aggregation Consortium)RTN1 (select the gene name)
Genetic variants : HAPMAP6252
Genomic Variants (DGV)RTN1 [DGVbeta]
DECIPHERRTN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRTN1 
Mutations
ICGC Data PortalRTN1 
TCGA Data PortalRTN1 
Broad Tumor PortalRTN1
OASIS PortalRTN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRTN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRTN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RTN1
DgiDB (Drug Gene Interaction Database)RTN1
DoCM (Curated mutations)RTN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RTN1 (select a term)
intoGenRTN1
Cancer3DRTN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600865   
Orphanet
MedgenRTN1
Genetic Testing Registry RTN1
NextProtQ16799 [Medical]
TSGene6252
GENETestsRTN1
Target ValidationRTN1
Huge Navigator RTN1 [HugePedia]
snp3D : Map Gene to Disease6252
BioCentury BCIQRTN1
ClinGenRTN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6252
Chemical/Pharm GKB GenePA34880
Clinical trialRTN1
Miscellaneous
canSAR (ICR)RTN1 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRTN1
EVEXRTN1
GoPubMedRTN1
iHOPRTN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:54:08 CEST 2017

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