Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RTN3 (reticulon 3)

Identity

Alias_symbol (synonym)NSPL2
NSPLII
ASYIP
HAP
RTN3-A1
Other alias
HGNC (Hugo) RTN3
LocusID (NCBI) 10313
Atlas_Id 47562
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 63681450 and ends at 63759891 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NDUFA4 (7p21.3) / RTN3 (11q13.1)NDUFS4 (5q11.2) / RTN3 (11q13.1)NFASC (1q32.1) / RTN3 (11q13.1)
RTN3 (11q13.1) / HELLS (10q23.33)RTN3 (11q13.1) / HRASLS5 (11q12.3)RTN3 (11q13.1) / TCERG1 (5q32)
ZNF736 (7q11.21) / RTN3 (11q13.1)RTN3 11q13.1 / HRASLS5 11q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RTN3   10469
Cards
Entrez_Gene (NCBI)RTN3  10313  reticulon 3
AliasesASYIP; HAP; NSPL2; NSPLII; 
RTN3-A1
GeneCards (Weizmann)RTN3
Ensembl hg19 (Hinxton)ENSG00000133318 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000133318 [Gene_View]  chr11:63681450-63759891 [Contig_View]  RTN3 [Vega]
ICGC DataPortalENSG00000133318
TCGA cBioPortalRTN3
AceView (NCBI)RTN3
Genatlas (Paris)RTN3
WikiGenes10313
SOURCE (Princeton)RTN3
Genetics Home Reference (NIH)RTN3
Genomic and cartography
GoldenPath hg38 (UCSC)RTN3  -     chr11:63681450-63759891 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RTN3  -     11q13.1   [Description]    (hg19-Feb_2009)
EnsemblRTN3 - 11q13.1 [CytoView hg19]  RTN3 - 11q13.1 [CytoView hg38]
Mapping of homologs : NCBIRTN3 [Mapview hg19]  RTN3 [Mapview hg38]
OMIM604249   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001265589 NM_001265590 NM_001265591 NM_006054 NM_201428 NM_201429 NM_201430
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RTN3
Cluster EST : UnigeneHs.743229 [ NCBI ]
CGAP (NCI)Hs.743229
Alternative Splicing GalleryENSG00000133318
Gene ExpressionRTN3 [ NCBI-GEO ]   RTN3 [ EBI - ARRAY_EXPRESS ]   RTN3 [ SEEK ]   RTN3 [ MEM ]
Gene Expression Viewer (FireBrowse)RTN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10313
GTEX Portal (Tissue expression)RTN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95197   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95197  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95197
Splice isoforms : SwissVarO95197
PhosPhoSitePlusO95197
Domaine pattern : Prosite (Expaxy)RETICULON (PS50845)   
Domains : Interpro (EBI)Reticulon   
Domain families : Pfam (Sanger)Reticulon (PF02453)   
Domain families : Pfam (NCBI)pfam02453   
Conserved Domain (NCBI)RTN3
DMDM Disease mutations10313
Blocks (Seattle)RTN3
SuperfamilyO95197
Human Protein AtlasENSG00000133318
Peptide AtlasO95197
HPRD18516
IPIIPI00743293   IPI00398795   IPI00028946   IPI00412154   IPI00394896   IPI00394897   IPI00816394   IPI01009279   IPI01010161   IPI00922617   IPI01014910   IPI01015616   IPI01015692   
Protein Interaction databases
DIP (DOE-UCLA)O95197
IntAct (EBI)O95197
FunCoupENSG00000133318
BioGRIDRTN3
STRING (EMBL)RTN3
ZODIACRTN3
Ontologies - Pathways
QuickGOO95197
Ontology : AmiGOGolgi membrane  protein binding  extracellular space  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  apoptotic process  integral component of membrane  viral process  vesicle-mediated transport  extracellular exosome  endoplasmic reticulum tubular network organization  endoplasmic reticulum tubular network formation  
Ontology : EGO-EBIGolgi membrane  protein binding  extracellular space  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  apoptotic process  integral component of membrane  viral process  vesicle-mediated transport  extracellular exosome  endoplasmic reticulum tubular network organization  endoplasmic reticulum tubular network formation  
NDEx NetworkRTN3
Atlas of Cancer Signalling NetworkRTN3
Wikipedia pathwaysRTN3
Orthology - Evolution
OrthoDB10313
GeneTree (enSembl)ENSG00000133318
Phylogenetic Trees/Animal Genes : TreeFamRTN3
HOVERGENO95197
HOGENOMO95197
Homologs : HomoloGeneRTN3
Homology/Alignments : Family Browser (UCSC)RTN3
Gene fusions - Rearrangements
Fusion : MitelmanNFASC/RTN3 [1q32.1/11q13.1]  [t(1;11)(q32;q13)]  
Fusion : MitelmanRTN3/HRASLS5 [11q13.1/11q12.3]  [t(11;11)(q12;q13)]  
Fusion: TCGARTN3 11q13.1 HRASLS5 11q12.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRTN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RTN3
dbVarRTN3
ClinVarRTN3
1000_GenomesRTN3 
Exome Variant ServerRTN3
ExAC (Exome Aggregation Consortium)RTN3 (select the gene name)
Genetic variants : HAPMAP10313
Genomic Variants (DGV)RTN3 [DGVbeta]
DECIPHERRTN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRTN3 
Mutations
ICGC Data PortalRTN3 
TCGA Data PortalRTN3 
Broad Tumor PortalRTN3
OASIS PortalRTN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRTN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRTN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RTN3
DgiDB (Drug Gene Interaction Database)RTN3
DoCM (Curated mutations)RTN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RTN3 (select a term)
intoGenRTN3
Cancer3DRTN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604249   
Orphanet
MedgenRTN3
Genetic Testing Registry RTN3
NextProtO95197 [Medical]
TSGene10313
GENETestsRTN3
Target ValidationRTN3
Huge Navigator RTN3 [HugePedia]
snp3D : Map Gene to Disease10313
BioCentury BCIQRTN3
ClinGenRTN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10313
Chemical/Pharm GKB GenePA34882
Clinical trialRTN3
Miscellaneous
canSAR (ICR)RTN3 (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRTN3
EVEXRTN3
GoPubMedRTN3
iHOPRTN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:13:34 CEST 2017

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