RTRAF (RNA transcription, translation and transport factor)

2017-10-01 Affiliation

HGNC

RTRAF

LOCATION

14q22.1

LOCUSID

51637

ALIAS

C14orf166,CGI-99,CGI99,CLE,CLE7,LCRP369,RLLM1,hCLE,hCLE1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

dbSNP: 51637
ClinVar: 51637
TCGA: ENSG00000087302
COSMIC: RTRAF

Pathway	Source	External ID
Gene Expression	REACTOME	R-HSA-74160
tRNA processing	REACTOME	R-HSA-72306
tRNA processing in the nucleus	REACTOME	R-HSA-6784531

Not detected

Low

Medium

High

Pubmed ID	Year	Title	Citations
21823664	2011	Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein.	23
19152423	2009	Proteomic profiling in pancreatic cancer with and without lymph node metastasis.	22
24608264	2014	hCLE/C14orf166 associates with DDX1-HSPC117-FAM98B in a novel transcription-dependent shuttling RNA-transporting complex.	19
21900157	2011	Cellular human CLE/C14orf166 protein interacts with influenza virus polymerase and is required for viral replication.	18
15147888	2004	A novel ninein-interaction protein, CGI-99, blocks ninein phosphorylation by GSK3beta and is highly expressed in brain tumors.	14
26219895	2016	C14ORF166 overexpression is associated with pelvic lymph node metastasis and poor prognosis in uterine cervical cancer.	8
26905879	2016	C14orf166 is a high-risk biomarker for bladder cancer and promotes bladder cancer cell proliferation.	5
25964093	2015	Overexpression of chromosome 14 open reading frame 166 correlates with disease progression and poorer prognosis in human NPC.	3
26864902	2016	hCLE/C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles.	2
26883017	2016	C14orf166 overexpression correlates with tumor progression and poor prognosis of breast cancer.	1

Dessen P

RTRAF (RNA transcription, translation and transport factor)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01