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RUFY2 (RUN and FYVE domain containing 2)

Identity

Alias (NCBI)RABIP4R
ZFYVE13
HGNC (Hugo) RUFY2
HGNC Alias symbRABIP4R
FLJ10063
KIAA1537
ZFYVE13
LocusID (NCBI) 55680
Atlas_Id 72933
Location 10q21.3  [Link to chromosome band 10q21]
Location_base_pair Starts at 68343518 and ends at 68407189 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EZH2 (7q36.1) / RUFY2 (10q21.3)HERC4 (10q21.3) / RUFY2 (10q21.3)RUFY2 (10q21.3) / HNRNPH3 (10q21.3)
RUFY2 (10q21.3) / LOC100506713 ()RUFY2 (10q21.3) / RUFY2 (10q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RUFY2   19761
Cards
Entrez_Gene (NCBI)RUFY2    RUN and FYVE domain containing 2
AliasesRABIP4R; ZFYVE13
GeneCards (Weizmann)RUFY2
Ensembl hg19 (Hinxton)ENSG00000204130 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204130 [Gene_View]  ENSG00000204130 [Sequence]  chr10:68343518-68407189 [Contig_View]  RUFY2 [Vega]
ICGC DataPortalENSG00000204130
TCGA cBioPortalRUFY2
AceView (NCBI)RUFY2
Genatlas (Paris)RUFY2
SOURCE (Princeton)RUFY2
Genetics Home Reference (NIH)RUFY2
Genomic and cartography
GoldenPath hg38 (UCSC)RUFY2  -     chr10:68343518-68407189 -  10q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RUFY2  -     10q21.3   [Description]    (hg19-Feb_2009)
GoldenPathRUFY2 - 10q21.3 [CytoView hg19]  RUFY2 - 10q21.3 [CytoView hg38]
ImmunoBaseENSG00000204130
Genome Data Viewer NCBIRUFY2 [Mapview hg19]  
OMIM610328   
Gene and transcription
Genbank (Entrez)AB040970 AF411980 AF461266 AK055646 AK091629
RefSeq transcript (Entrez)NM_001042417 NM_001278225 NM_001330103 NM_017987
Consensus coding sequences : CCDS (NCBI)RUFY2
Gene ExpressionRUFY2 [ NCBI-GEO ]   RUFY2 [ EBI - ARRAY_EXPRESS ]   RUFY2 [ SEEK ]   RUFY2 [ MEM ]
Gene Expression Viewer (FireBrowse)RUFY2 [ Firebrowse - Broad ]
GenevisibleExpression of RUFY2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55680
GTEX Portal (Tissue expression)RUFY2
Human Protein AtlasENSG00000204130-RUFY2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WXA3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WXA3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WXA3
PhosPhoSitePlusQ8WXA3
Domaine pattern : Prosite (Expaxy)RUN (PS50826)    ZF_FYVE (PS50178)   
Domains : Interpro (EBI)Run_dom    Run_dom_sf    Znf_FYVE    Znf_FYVE-rel    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)FYVE (PF01363)    RUN (PF02759)   
Domain families : Pfam (NCBI)pfam01363    pfam02759   
Domain families : Smart (EMBL)FYVE (SM00064)  RUN (SM00593)  
Conserved Domain (NCBI)RUFY2
SuperfamilyQ8WXA3
AlphaFold pdb e-kbQ8WXA3   
Human Protein Atlas [tissue]ENSG00000204130-RUFY2 [tissue]
HPRD11526
Protein Interaction databases
DIP (DOE-UCLA)Q8WXA3
IntAct (EBI)Q8WXA3
BioGRIDRUFY2
STRING (EMBL)RUFY2
ZODIACRUFY2
Ontologies - Pathways
QuickGOQ8WXA3
Ontology : AmiGOnucleus  cytoplasm  cytoplasm  endosome  biological_process  SH3 domain binding  regulation of endocytosis  metal ion binding  
Ontology : EGO-EBInucleus  cytoplasm  cytoplasm  endosome  biological_process  SH3 domain binding  regulation of endocytosis  metal ion binding  
NDEx NetworkRUFY2
Atlas of Cancer Signalling NetworkRUFY2
Wikipedia pathwaysRUFY2
Orthology - Evolution
OrthoDB55680
GeneTree (enSembl)ENSG00000204130
Phylogenetic Trees/Animal Genes : TreeFamRUFY2
Homologs : HomoloGeneRUFY2
Homology/Alignments : Family Browser (UCSC)RUFY2
Gene fusions - Rearrangements
Fusion : QuiverRUFY2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRUFY2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RUFY2
dbVarRUFY2
ClinVarRUFY2
MonarchRUFY2
1000_GenomesRUFY2 
Exome Variant ServerRUFY2
GNOMAD BrowserENSG00000204130
Varsome BrowserRUFY2
ACMGRUFY2 variants
VarityQ8WXA3
Genomic Variants (DGV)RUFY2 [DGVbeta]
DECIPHERRUFY2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRUFY2 
Mutations
ICGC Data PortalRUFY2 
TCGA Data PortalRUFY2 
Broad Tumor PortalRUFY2
OASIS PortalRUFY2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRUFY2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRUFY2
Mutations and Diseases : HGMDRUFY2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRUFY2
DgiDB (Drug Gene Interaction Database)RUFY2
DoCM (Curated mutations)RUFY2
CIViC (Clinical Interpretations of Variants in Cancer)RUFY2
Cancer3DRUFY2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610328   
Orphanet
DisGeNETRUFY2
MedgenRUFY2
Genetic Testing Registry RUFY2
NextProtQ8WXA3 [Medical]
GENETestsRUFY2
Target ValidationRUFY2
Huge Navigator RUFY2 [HugePedia]
ClinGenRUFY2
Clinical trials, drugs, therapy
MyCancerGenomeRUFY2
Protein Interactions : CTDRUFY2
Pharm GKB GenePA134935922
PharosQ8WXA3
Clinical trialRUFY2
Miscellaneous
canSAR (ICR)RUFY2
HarmonizomeRUFY2
DataMed IndexRUFY2
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRUFY2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:19:39 CEST 2021

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