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RUFY3 (RUN and FYVE domain containing 3)

Identity

Alias_symbol (synonym)RIPx
KIAA0871
Singar1
ZFYVE30
Other aliasRIPX
SINGAR1
HGNC (Hugo) RUFY3
LocusID (NCBI) 22902
Atlas_Id 55544
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 70721842 and ends at 70808622 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EPHA5 (4q13.1) / RUFY3 (4q13.3)PDHB (3p14.3) / RUFY3 (4q13.3)RUFY3 (4q13.3) / TMPRSS11A (4q13.2)
RUFY3 (4q13.3) / ZNF462 (9q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RUFY3   30285
Cards
Entrez_Gene (NCBI)RUFY3  22902  RUN and FYVE domain containing 3
AliasesRIPX; SINGAR1; ZFYVE30
GeneCards (Weizmann)RUFY3
Ensembl hg19 (Hinxton)ENSG00000018189 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000018189 [Gene_View]  chr4:70721842-70808622 [Contig_View]  RUFY3 [Vega]
ICGC DataPortalENSG00000018189
TCGA cBioPortalRUFY3
AceView (NCBI)RUFY3
Genatlas (Paris)RUFY3
WikiGenes22902
SOURCE (Princeton)RUFY3
Genetics Home Reference (NIH)RUFY3
Genomic and cartography
GoldenPath hg38 (UCSC)RUFY3  -     chr4:70721842-70808622 +  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RUFY3  -     4q13.3   [Description]    (hg19-Feb_2009)
EnsemblRUFY3 - 4q13.3 [CytoView hg19]  RUFY3 - 4q13.3 [CytoView hg38]
Mapping of homologs : NCBIRUFY3 [Mapview hg19]  RUFY3 [Mapview hg38]
OMIM611194   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001037442 NM_001130709 NM_001291993 NM_001291994 NM_001345840 NM_014961
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)RUFY3
Cluster EST : UnigeneHs.740904 [ NCBI ]
CGAP (NCI)Hs.740904
Alternative Splicing GalleryENSG00000018189
Gene ExpressionRUFY3 [ NCBI-GEO ]   RUFY3 [ EBI - ARRAY_EXPRESS ]   RUFY3 [ SEEK ]   RUFY3 [ MEM ]
Gene Expression Viewer (FireBrowse)RUFY3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22902
GTEX Portal (Tissue expression)RUFY3
Human Protein AtlasENSG00000018189-RUFY3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7L099   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7L099  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7L099
Splice isoforms : SwissVarQ7L099
PhosPhoSitePlusQ7L099
Domaine pattern : Prosite (Expaxy)RUN (PS50826)   
Domains : Interpro (EBI)Run_dom   
Domain families : Pfam (Sanger)RUN (PF02759)   
Domain families : Pfam (NCBI)pfam02759   
Domain families : Smart (EMBL)RUN (SM00593)  
Conserved Domain (NCBI)RUFY3
DMDM Disease mutations22902
Blocks (Seattle)RUFY3
SuperfamilyQ7L099
Human Protein Atlas [tissue]ENSG00000018189-RUFY3 [tissue]
Peptide AtlasQ7L099
HPRD15251
IPIIPI00033573   IPI00908586   IPI00455620   IPI00965333   IPI00967429   IPI00964440   IPI00964732   IPI00965090   IPI00967069   
Protein Interaction databases
DIP (DOE-UCLA)Q7L099
IntAct (EBI)Q7L099
FunCoupENSG00000018189
BioGRIDRUFY3
STRING (EMBL)RUFY3
ZODIACRUFY3
Ontologies - Pathways
QuickGOQ7L099
Ontology : AmiGOprotein binding  cytoplasm  cytosol  actin filament organization  endomembrane system  membrane  lamellipodium  cell junction  filopodium  positive regulation of cell migration  axon  dendrite  growth cone  perikaryon  positive regulation of axon extension  negative regulation of axonogenesis  invadopodium  positive regulation of intracellular protein transport  regulation of establishment of cell polarity  
Ontology : EGO-EBIprotein binding  cytoplasm  cytosol  actin filament organization  endomembrane system  membrane  lamellipodium  cell junction  filopodium  positive regulation of cell migration  axon  dendrite  growth cone  perikaryon  positive regulation of axon extension  negative regulation of axonogenesis  invadopodium  positive regulation of intracellular protein transport  regulation of establishment of cell polarity  
NDEx NetworkRUFY3
Atlas of Cancer Signalling NetworkRUFY3
Wikipedia pathwaysRUFY3
Orthology - Evolution
OrthoDB22902
GeneTree (enSembl)ENSG00000018189
Phylogenetic Trees/Animal Genes : TreeFamRUFY3
HOVERGENQ7L099
HOGENOMQ7L099
Homologs : HomoloGeneRUFY3
Homology/Alignments : Family Browser (UCSC)RUFY3
Gene fusions - Rearrangements
Tumor Fusion PortalRUFY3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRUFY3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RUFY3
dbVarRUFY3
ClinVarRUFY3
1000_GenomesRUFY3 
Exome Variant ServerRUFY3
ExAC (Exome Aggregation Consortium)ENSG00000018189
GNOMAD BrowserENSG00000018189
Genetic variants : HAPMAP22902
Genomic Variants (DGV)RUFY3 [DGVbeta]
DECIPHERRUFY3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRUFY3 
Mutations
ICGC Data PortalRUFY3 
TCGA Data PortalRUFY3 
Broad Tumor PortalRUFY3
OASIS PortalRUFY3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRUFY3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRUFY3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RUFY3
DgiDB (Drug Gene Interaction Database)RUFY3
DoCM (Curated mutations)RUFY3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RUFY3 (select a term)
intoGenRUFY3
Cancer3DRUFY3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611194   
Orphanet
DisGeNETRUFY3
MedgenRUFY3
Genetic Testing Registry RUFY3
NextProtQ7L099 [Medical]
TSGene22902
GENETestsRUFY3
Target ValidationRUFY3
Huge Navigator RUFY3 [HugePedia]
snp3D : Map Gene to Disease22902
BioCentury BCIQRUFY3
ClinGenRUFY3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22902
Chemical/Pharm GKB GenePA142670961
Clinical trialRUFY3
Miscellaneous
canSAR (ICR)RUFY3 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRUFY3
EVEXRUFY3
GoPubMedRUFY3
iHOPRUFY3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:33:17 CET 2017

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