| Nomenclature |
HGNC (Hugo) | RUNX3 10473 |
| Cards |
Entrez_Gene (NCBI) | RUNX3 RUNX family transcription factor 3 |
Aliases | AML2; CBFA3; PEBP2aC |
GeneCards (Weizmann) | RUNX3 |
Ensembl hg19 (Hinxton) | ENSG00000020633 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000020633 [Gene_View]  ENSG00000020633 [Sequence] chr1:24899511-24930276 [Contig_View] RUNX3 [Vega] |
ICGC DataPortal | ENSG00000020633 |
TCGA cBioPortal | RUNX3 |
AceView (NCBI) | RUNX3 |
Genatlas (Paris) | RUNX3 |
SOURCE (Princeton) | RUNX3 |
Genetics Home Reference (NIH) | RUNX3 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | RUNX3 - chr1:24899511-24930276 - 1p36.11 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | RUNX3 - 1p36.11 [Description] (hg19-Feb_2009) |
GoldenPath | RUNX3 - 1p36.11 [CytoView hg19] RUNX3 - 1p36.11 [CytoView hg38] |
ImmunoBase | ENSG00000020633 |
genome Data Viewer NCBI | RUNX3 [Mapview hg19] |
OMIM | 600210 |
| Gene and transcription |
Genbank (Entrez) | AF022726 AI375031 AJ001432 AK091829 AK300056 |
RefSeq transcript (Entrez) | NM_001031680 NM_001320672 NM_004350 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | RUNX3 |
Alternative Splicing Gallery | ENSG00000020633 |
Gene Expression | RUNX3 [ NCBI-GEO ] RUNX3 [ EBI - ARRAY_EXPRESS ]
RUNX3 [ SEEK ] RUNX3 [ MEM ] |
Gene Expression Viewer (FireBrowse) | RUNX3 [ Firebrowse - Broad ] |
Genevisible | Expression of RUNX3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 864 |
GTEX Portal (Tissue expression) | RUNX3 |
Human Protein Atlas | ENSG00000020633-RUNX3 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q13761 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q13761 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q13761 |
Splice isoforms : SwissVar | Q13761 |
PhosPhoSitePlus | Q13761 |
Domaine pattern : Prosite (Expaxy) | RUNT (PS51062) |
Domains : Interpro (EBI) | AML1_Runt p53-like_TF_DNA-bd p53/RUNT-type_TF_DNA-bd_sf Runt_dom RunxI_C_dom TF_Runt-rel_RUNX |
Domain families : Pfam (Sanger) | Runt (PF00853) RunxI (PF08504) |
Domain families : Pfam (NCBI) | pfam00853 pfam08504 |
Conserved Domain (NCBI) | RUNX3 |
Blocks (Seattle) | RUNX3 |
PDB (RSDB) | 5W69 |
PDB Europe | 5W69 |
PDB (PDBSum) | 5W69 |
PDB (IMB) | 5W69 |
Structural Biology KnowledgeBase | 5W69 |
SCOP (Structural Classification of Proteins) | 5W69 |
CATH (Classification of proteins structures) | 5W69 |
Superfamily | Q13761 |
Human Protein Atlas [tissue] | ENSG00000020633-RUNX3 [tissue] |
Peptide Atlas | Q13761 |
HPRD | 02565 |
IPI | IPI00004015 IPI00218386 IPI00908417 IPI01013326 IPI00816617 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q13761 |
IntAct (EBI) | Q13761 |
BioGRID | RUNX3 |
STRING (EMBL) | RUNX3 |
ZODIAC | RUNX3 |
| Ontologies - Pathways |
QuickGO | Q13761 |
Ontology : AmiGO | negative regulation of transcription by RNA polymerase II chromatin chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific ossification chondrocyte differentiation DNA-binding transcription factor activity protein binding ATP binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II protein phosphorylation core-binding factor complex hemopoiesis neuron differentiation intracellular membrane-bounded organelle negative regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of CD8-positive, alpha-beta T cell differentiation regulation of cell differentiation negative regulation of cell cycle positive regulation of transcription, DNA-templated peripheral nervous system neuron development negative regulation of epithelial cell proliferation response to transforming growth factor beta sequence-specific double-stranded DNA binding |
Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II chromatin chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific ossification chondrocyte differentiation DNA-binding transcription factor activity protein binding ATP binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II protein phosphorylation core-binding factor complex hemopoiesis neuron differentiation intracellular membrane-bounded organelle negative regulation of CD4-positive, alpha-beta T cell differentiation positive regulation of CD8-positive, alpha-beta T cell differentiation regulation of cell differentiation negative regulation of cell cycle positive regulation of transcription, DNA-templated peripheral nervous system neuron development negative regulation of epithelial cell proliferation response to transforming growth factor beta sequence-specific double-stranded DNA binding |
NDEx Network | RUNX3 |
Atlas of Cancer Signalling Network | RUNX3 |
Wikipedia pathways | RUNX3 |
| Orthology - Evolution |
OrthoDB | 864 |
GeneTree (enSembl) | ENSG00000020633 |
Phylogenetic Trees/Animal Genes : TreeFam | RUNX3 |
HOGENOM | Q13761 |
Homologs : HomoloGene | RUNX3 |
Homology/Alignments : Family Browser (UCSC) | RUNX3 |
| Gene fusions - Rearrangements |
Fusion : Quiver | RUNX3 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | RUNX3 [hg38] |
dbVar | RUNX3 |
ClinVar | RUNX3 |
Monarch | RUNX3 |
1000_Genomes | RUNX3 |
Exome Variant Server | RUNX3 |
GNOMAD Browser | ENSG00000020633 |
Varsome Browser | RUNX3 |
Genomic Variants (DGV) | RUNX3 [DGVbeta] |
DECIPHER | RUNX3 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | RUNX3 |
| Mutations |
ICGC Data Portal | RUNX3 |
TCGA Data Portal | RUNX3 |
Broad Tumor Portal | RUNX3 |
OASIS Portal | RUNX3 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | RUNX3 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | RUNX3 |
Mutations and Diseases : HGMD | RUNX3 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search RUNX3 |
DgiDB (Drug Gene Interaction Database) | RUNX3 |
DoCM (Curated mutations) | RUNX3 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | RUNX3 (select a term) |
intoGen | RUNX3 |
Cancer3D | RUNX3(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
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OMIM | 600210 |
Orphanet | |
DisGeNET | RUNX3 |
Medgen | RUNX3 |
Genetic Testing Registry | RUNX3
|
NextProt | Q13761 [Medical] |
GENETests | RUNX3 |
Target Validation | RUNX3 |
Huge Navigator |
RUNX3 [HugePedia] |
ClinGen | RUNX3 |
| Clinical trials, drugs, therapy |
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MyCancerGenome | RUNX3 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA34886 |
Pharos | Q13761 |
Clinical trial | RUNX3 |
| Miscellaneous |
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canSAR (ICR) | RUNX3 (select the gene name) |
Harmonizome | RUNX3 |
DataMed Index | RUNX3 |
| Probes |
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| Litterature |
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PubMed | 381 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | RUNX3 |