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RUSC1 (RUN and SH3 domain containing 1)

Identity

Alias (NCBI)NESCA
HGNC (Hugo) RUSC1
HGNC Alias symbNESCA
LocusID (NCBI) 23623
Atlas_Id 58042
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 155323937 and ends at 155331118 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EFNA4 (1q22) / RUSC1 (1q22)OPRL1 (20q13.33) / RUSC1 (1q22)RDH13 (19q13.42) / RUSC1 (1q22)
RUSC1 (1q22) / MT1X (16q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RUSC1   17153
Cards
Entrez_Gene (NCBI)RUSC1    RUN and SH3 domain containing 1
AliasesNESCA
GeneCards (Weizmann)RUSC1
Ensembl hg19 (Hinxton)ENSG00000160753 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000160753 [Gene_View]  ENSG00000160753 [Sequence]  chr1:155323937-155331118 [Contig_View]  RUSC1 [Vega]
ICGC DataPortalENSG00000160753
TCGA cBioPortalRUSC1
AceView (NCBI)RUSC1
Genatlas (Paris)RUSC1
SOURCE (Princeton)RUSC1
Genetics Home Reference (NIH)RUSC1
Genomic and cartography
GoldenPath hg38 (UCSC)RUSC1  -     chr1:155323937-155331118 +  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RUSC1  -     1q22   [Description]    (hg19-Feb_2009)
GoldenPathRUSC1 - 1q22 [CytoView hg19]  RUSC1 - 1q22 [CytoView hg38]
ImmunoBaseENSG00000160753
Genome Data Viewer NCBIRUSC1 [Mapview hg19]  
OMIM617318   
Gene and transcription
Genbank (Entrez)AB026894 AK055451 AK074485 AK074982 AK093777
RefSeq transcript (Entrez)NM_001105203 NM_001105204 NM_001105205 NM_001278227 NM_001278228 NM_001278229 NM_001278230 NM_014328
Consensus coding sequences : CCDS (NCBI)RUSC1
Gene ExpressionRUSC1 [ NCBI-GEO ]   RUSC1 [ EBI - ARRAY_EXPRESS ]   RUSC1 [ SEEK ]   RUSC1 [ MEM ]
Gene Expression Viewer (FireBrowse)RUSC1 [ Firebrowse - Broad ]
GenevisibleExpression of RUSC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23623
GTEX Portal (Tissue expression)RUSC1
Human Protein AtlasENSG00000160753-RUSC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVN2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVN2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVN2
PhosPhoSitePlusQ9BVN2
Domaine pattern : Prosite (Expaxy)RUN (PS50826)    SH3 (PS50002)   
Domains : Interpro (EBI)Run_dom    Run_dom_sf    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)RUN (PF02759)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam02759    pfam14604   
Domain families : Smart (EMBL)RUN (SM00593)  SH3 (SM00326)  
Conserved Domain (NCBI)RUSC1
PDB (RSDB)4GIW   
PDB Europe4GIW   
PDB (PDBSum)4GIW   
PDB (IMB)4GIW   
Structural Biology KnowledgeBase4GIW   
SCOP (Structural Classification of Proteins)4GIW   
CATH (Classification of proteins structures)4GIW   
SuperfamilyQ9BVN2
AlphaFold pdb e-kbQ9BVN2   
Human Protein Atlas [tissue]ENSG00000160753-RUSC1 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9BVN2
IntAct (EBI)Q9BVN2
BioGRIDRUSC1
STRING (EMBL)RUSC1
ZODIACRUSC1
Ontologies - Pathways
QuickGOQ9BVN2
Ontology : AmiGOprotein polyubiquitination  actin binding  protein binding  nucleus  early endosome  Golgi apparatus  cytosol  microtubule  postsynaptic density  microtubule cytoskeleton  cytoplasmic vesicle  cytoplasmic vesicle  
Ontology : EGO-EBIprotein polyubiquitination  actin binding  protein binding  nucleus  early endosome  Golgi apparatus  cytosol  microtubule  postsynaptic density  microtubule cytoskeleton  cytoplasmic vesicle  cytoplasmic vesicle  
NDEx NetworkRUSC1
Atlas of Cancer Signalling NetworkRUSC1
Wikipedia pathwaysRUSC1
Orthology - Evolution
OrthoDB23623
GeneTree (enSembl)ENSG00000160753
Phylogenetic Trees/Animal Genes : TreeFamRUSC1
Homologs : HomoloGeneRUSC1
Homology/Alignments : Family Browser (UCSC)RUSC1
Gene fusions - Rearrangements
Fusion : QuiverRUSC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRUSC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RUSC1
dbVarRUSC1
ClinVarRUSC1
MonarchRUSC1
1000_GenomesRUSC1 
Exome Variant ServerRUSC1
GNOMAD BrowserENSG00000160753
Varsome BrowserRUSC1
ACMGRUSC1 variants
VarityQ9BVN2
Genomic Variants (DGV)RUSC1 [DGVbeta]
DECIPHERRUSC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRUSC1 
Mutations
ICGC Data PortalRUSC1 
TCGA Data PortalRUSC1 
Broad Tumor PortalRUSC1
OASIS PortalRUSC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRUSC1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRUSC1
Mutations and Diseases : HGMDRUSC1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRUSC1
DgiDB (Drug Gene Interaction Database)RUSC1
DoCM (Curated mutations)RUSC1
CIViC (Clinical Interpretations of Variants in Cancer)RUSC1
Cancer3DRUSC1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617318   
Orphanet
DisGeNETRUSC1
MedgenRUSC1
Genetic Testing Registry RUSC1
NextProtQ9BVN2 [Medical]
GENETestsRUSC1
Target ValidationRUSC1
Huge Navigator RUSC1 [HugePedia]
ClinGenRUSC1
Clinical trials, drugs, therapy
MyCancerGenomeRUSC1
Protein Interactions : CTDRUSC1
Pharm GKB GenePA134947113
PharosQ9BVN2
Clinical trialRUSC1
Miscellaneous
canSAR (ICR)RUSC1
HarmonizomeRUSC1
DataMed IndexRUSC1
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRUSC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:29:51 CEST 2021

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