Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

RUSC1 (RUN and SH3 domain containing 1)

Identity

Alias_symbol (synonym)NESCA
Other alias
HGNC (Hugo) RUSC1
LocusID (NCBI) 23623
Atlas_Id 72940
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 155290640 and ends at 155300909 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EFNA4 (1q22) / RUSC1 (1q22)OPRL1 (20q13.33) / RUSC1 (1q22)RDH13 (19q13.42) / RUSC1 (1q22)
RUSC1 (1q22) / MT1X (16q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RUSC1   17153
Cards
Entrez_Gene (NCBI)RUSC1  23623  RUN and SH3 domain containing 1
AliasesNESCA
GeneCards (Weizmann)RUSC1
Ensembl hg19 (Hinxton)ENSG00000160753 [Gene_View]  chr1:155290640-155300909 [Contig_View]  RUSC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000160753 [Gene_View]  chr1:155290640-155300909 [Contig_View]  RUSC1 [Vega]
ICGC DataPortalENSG00000160753
TCGA cBioPortalRUSC1
AceView (NCBI)RUSC1
Genatlas (Paris)RUSC1
WikiGenes23623
SOURCE (Princeton)RUSC1
Genetics Home Reference (NIH)RUSC1
Genomic and cartography
GoldenPath hg19 (UCSC)RUSC1  -     chr1:155290640-155300909 +  1q22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RUSC1  -     1q22   [Description]    (hg38-Dec_2013)
EnsemblRUSC1 - 1q22 [CytoView hg19]  RUSC1 - 1q22 [CytoView hg38]
Mapping of homologs : NCBIRUSC1 [Mapview hg19]  RUSC1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB026894 AK055451 AK074485 AK074982 AK093777
RefSeq transcript (Entrez)NM_001105203 NM_001105204 NM_001105205 NM_001278227 NM_001278228 NM_001278229 NM_001278230 NM_014328
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)RUSC1
Cluster EST : UnigeneHs.226499 [ NCBI ]
CGAP (NCI)Hs.226499
Alternative Splicing GalleryENSG00000160753
Gene ExpressionRUSC1 [ NCBI-GEO ]   RUSC1 [ EBI - ARRAY_EXPRESS ]   RUSC1 [ SEEK ]   RUSC1 [ MEM ]
Gene Expression Viewer (FireBrowse)RUSC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23623
GTEX Portal (Tissue expression)RUSC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVN2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVN2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVN2
Splice isoforms : SwissVarQ9BVN2
PhosPhoSitePlusQ9BVN2
Domaine pattern : Prosite (Expaxy)RUN (PS50826)    SH3 (PS50002)   
Domains : Interpro (EBI)Run    SH3_domain   
Domain families : Pfam (Sanger)RUN (PF02759)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam02759    pfam14604   
Domain families : Smart (EMBL)RUN (SM00593)  SH3 (SM00326)  
Conserved Domain (NCBI)RUSC1
DMDM Disease mutations23623
Blocks (Seattle)RUSC1
PDB (SRS)4GIW   
PDB (PDBSum)4GIW   
PDB (IMB)4GIW   
PDB (RSDB)4GIW   
Structural Biology KnowledgeBase4GIW   
SCOP (Structural Classification of Proteins)4GIW   
CATH (Classification of proteins structures)4GIW   
SuperfamilyQ9BVN2
Human Protein AtlasENSG00000160753
Peptide AtlasQ9BVN2
HPRD10206
IPIIPI00425688   IPI00549392   IPI00936583   IPI00883817   IPI00514776   IPI00425689   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVN2
IntAct (EBI)Q9BVN2
FunCoupENSG00000160753
BioGRIDRUSC1
STRING (EMBL)RUSC1
ZODIACRUSC1
Ontologies - Pathways
QuickGOQ9BVN2
Ontology : AmiGOprotein polyubiquitination  actin binding  SH3/SH2 adaptor activity  protein binding  nucleus  cytoplasm  early endosome  Golgi apparatus  microtubule  positive regulation of signal transduction  postsynaptic density  microtubule cytoskeleton  cytoplasmic membrane-bounded vesicle  cell junction  cytoplasmic vesicle  postsynaptic membrane  
Ontology : EGO-EBIprotein polyubiquitination  actin binding  SH3/SH2 adaptor activity  protein binding  nucleus  cytoplasm  early endosome  Golgi apparatus  microtubule  positive regulation of signal transduction  postsynaptic density  microtubule cytoskeleton  cytoplasmic membrane-bounded vesicle  cell junction  cytoplasmic vesicle  postsynaptic membrane  
NDEx NetworkRUSC1
Atlas of Cancer Signalling NetworkRUSC1
Wikipedia pathwaysRUSC1
Orthology - Evolution
OrthoDB23623
GeneTree (enSembl)ENSG00000160753
Phylogenetic Trees/Animal Genes : TreeFamRUSC1
HOVERGENQ9BVN2
HOGENOMQ9BVN2
Homologs : HomoloGeneRUSC1
Homology/Alignments : Family Browser (UCSC)RUSC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRUSC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RUSC1
dbVarRUSC1
ClinVarRUSC1
1000_GenomesRUSC1 
Exome Variant ServerRUSC1
ExAC (Exome Aggregation Consortium)RUSC1 (select the gene name)
Genetic variants : HAPMAP23623
Genomic Variants (DGV)RUSC1 [DGVbeta]
DECIPHER (Syndromes)1:155290640-155300909  ENSG00000160753
CONAN: Copy Number AnalysisRUSC1 
Mutations
ICGC Data PortalRUSC1 
TCGA Data PortalRUSC1 
Broad Tumor PortalRUSC1
OASIS PortalRUSC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRUSC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRUSC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RUSC1
DgiDB (Drug Gene Interaction Database)RUSC1
DoCM (Curated mutations)RUSC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RUSC1 (select a term)
intoGenRUSC1
Cancer3DRUSC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenRUSC1
Genetic Testing Registry RUSC1
NextProtQ9BVN2 [Medical]
TSGene23623
GENETestsRUSC1
Huge Navigator RUSC1 [HugePedia]
snp3D : Map Gene to Disease23623
BioCentury BCIQRUSC1
ClinGenRUSC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23623
Chemical/Pharm GKB GenePA134947113
Clinical trialRUSC1
Miscellaneous
canSAR (ICR)RUSC1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRUSC1
EVEXRUSC1
GoPubMedRUSC1
iHOPRUSC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:42:10 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.