Atlas of Genetics and Cytogenetics in Oncology and Haematology


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RXFP1 (relaxin/insulin like family peptide receptor 1)

Identity

Alias_namesLGR7
leucine-rich repeat-containing G protein-coupled receptor 7
Alias_symbol (synonym)RXFPR1
Other alias
HGNC (Hugo) RXFP1
LocusID (NCBI) 59350
Atlas_Id 50924
Location 4q32.1  [Link to chromosome band 4q32]
Location_base_pair Starts at 159442866 and ends at 159574521 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LRBA (4q31.3) / RXFP1 (4q32.1)LRBA 4q31.3 / RXFP1 4q32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)RXFP1   19718
Cards
Entrez_Gene (NCBI)RXFP1  59350  relaxin/insulin like family peptide receptor 1
AliasesLGR7; RXFPR1
GeneCards (Weizmann)RXFP1
Ensembl hg19 (Hinxton)ENSG00000171509 [Gene_View]  chr4:159442866-159574521 [Contig_View]  RXFP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171509 [Gene_View]  chr4:159442866-159574521 [Contig_View]  RXFP1 [Vega]
ICGC DataPortalENSG00000171509
TCGA cBioPortalRXFP1
AceView (NCBI)RXFP1
Genatlas (Paris)RXFP1
WikiGenes59350
SOURCE (Princeton)RXFP1
Genetics Home Reference (NIH)RXFP1
Genomic and cartography
GoldenPath hg19 (UCSC)RXFP1  -     chr4:159442866-159574521 +  4q32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)RXFP1  -     4q32.1   [Description]    (hg38-Dec_2013)
EnsemblRXFP1 - 4q32.1 [CytoView hg19]  RXFP1 - 4q32.1 [CytoView hg38]
Mapping of homologs : NCBIRXFP1 [Mapview hg19]  RXFP1 [Mapview hg38]
OMIM606654   
Gene and transcription
Genbank (Entrez)AB208943 AF190500 AI653269 AK122647 AK294694
RefSeq transcript (Entrez)NM_001253727 NM_001253728 NM_001253729 NM_001253730 NM_001253732 NM_001253733 NM_021634
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_031835 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)RXFP1
Cluster EST : UnigeneHs.591686 [ NCBI ]
CGAP (NCI)Hs.591686
Alternative Splicing GalleryENSG00000171509
Gene ExpressionRXFP1 [ NCBI-GEO ]   RXFP1 [ EBI - ARRAY_EXPRESS ]   RXFP1 [ SEEK ]   RXFP1 [ MEM ]
Gene Expression Viewer (FireBrowse)RXFP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)59350
GTEX Portal (Tissue expression)RXFP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HBX9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HBX9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HBX9
Splice isoforms : SwissVarQ9HBX9
PhosPhoSitePlusQ9HBX9
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)    LDLRA_1 (PS01209)    LDLRA_2 (PS50068)    LRR (PS51450)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    L_dom-like    LDLR_class-A_CS    LDrepeatLR_classA_rpt    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT    Relaxin_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)    Ldl_recept_a (PF00057)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam00001    pfam00057    pfam13855   
Domain families : Smart (EMBL)LDLa (SM00192)  LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)RXFP1
DMDM Disease mutations59350
Blocks (Seattle)RXFP1
PDB (SRS)2JM4    2M7P   
PDB (PDBSum)2JM4    2M7P   
PDB (IMB)2JM4    2M7P   
PDB (RSDB)2JM4    2M7P   
Structural Biology KnowledgeBase2JM4    2M7P   
SCOP (Structural Classification of Proteins)2JM4    2M7P   
CATH (Classification of proteins structures)2JM4    2M7P   
SuperfamilyQ9HBX9
Human Protein AtlasENSG00000171509
Peptide AtlasQ9HBX9
HPRD05975
IPIIPI00219888   IPI00876893   IPI00654878   IPI00012456   IPI00916911   IPI00910652   IPI00965023   IPI00984452   
Protein Interaction databases
DIP (DOE-UCLA)Q9HBX9
IntAct (EBI)Q9HBX9
FunCoupENSG00000171509
BioGRIDRXFP1
STRING (EMBL)RXFP1
ZODIACRXFP1
Ontologies - Pathways
QuickGOQ9HBX9
Ontology : AmiGOG-protein coupled receptor activity  protein binding  plasma membrane  plasma membrane  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  integral component of membrane  metal ion binding  
Ontology : EGO-EBIG-protein coupled receptor activity  protein binding  plasma membrane  plasma membrane  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  integral component of membrane  metal ion binding  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkRXFP1
Atlas of Cancer Signalling NetworkRXFP1
Wikipedia pathwaysRXFP1
Orthology - Evolution
OrthoDB59350
GeneTree (enSembl)ENSG00000171509
Phylogenetic Trees/Animal Genes : TreeFamRXFP1
HOVERGENQ9HBX9
HOGENOMQ9HBX9
Homologs : HomoloGeneRXFP1
Homology/Alignments : Family Browser (UCSC)RXFP1
Gene fusions - Rearrangements
Fusion : MitelmanLRBA/RXFP1 [4q31.3/4q32.1]  [t(4;4)(q31;q32)]  
Fusion: TCGALRBA 4q31.3 RXFP1 4q32.1 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRXFP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RXFP1
dbVarRXFP1
ClinVarRXFP1
1000_GenomesRXFP1 
Exome Variant ServerRXFP1
ExAC (Exome Aggregation Consortium)RXFP1 (select the gene name)
Genetic variants : HAPMAP59350
Genomic Variants (DGV)RXFP1 [DGVbeta]
DECIPHER (Syndromes)4:159442866-159574521  ENSG00000171509
CONAN: Copy Number AnalysisRXFP1 
Mutations
ICGC Data PortalRXFP1 
TCGA Data PortalRXFP1 
Broad Tumor PortalRXFP1
OASIS PortalRXFP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRXFP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDRXFP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch RXFP1
DgiDB (Drug Gene Interaction Database)RXFP1
DoCM (Curated mutations)RXFP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)RXFP1 (select a term)
intoGenRXFP1
Cancer3DRXFP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606654   
Orphanet
MedgenRXFP1
Genetic Testing Registry RXFP1
NextProtQ9HBX9 [Medical]
TSGene59350
GENETestsRXFP1
Huge Navigator RXFP1 [HugePedia]
snp3D : Map Gene to Disease59350
BioCentury BCIQRXFP1
ClinGenRXFP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD59350
Chemical/Pharm GKB GenePA134868312
Clinical trialRXFP1
Miscellaneous
canSAR (ICR)RXFP1 (select the gene name)
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineRXFP1
EVEXRXFP1
GoPubMedRXFP1
iHOPRXFP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:25:58 CET 2017

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