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RXFP4 (relaxin family peptide/INSL5 receptor 4)

Identity

Alias (NCBI)GPCR142
GPR100
RLN3R2
RXFPR4
HGNC (Hugo) RXFP4
HGNC Alias symbGPCR142
RXFPR4
HGNC Previous nameGPR100
 RLN3R2
HGNC Previous nameG protein-coupled receptor 100
 relaxin 3 receptor 2
 relaxin family peptide receptor 4
LocusID (NCBI) 339403
Atlas_Id 72947
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 155941638 and ends at 155943086 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)RXFP4   14666
Cards
Entrez_Gene (NCBI)RXFP4    relaxin family peptide/INSL5 receptor 4
AliasesGPCR142; GPR100; RLN3R2; RXFPR4
GeneCards (Weizmann)RXFP4
Ensembl hg19 (Hinxton)ENSG00000173080 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173080 [Gene_View]  ENSG00000173080 [Sequence]  chr1:155941638-155943086 [Contig_View]  RXFP4 [Vega]
ICGC DataPortalENSG00000173080
TCGA cBioPortalRXFP4
AceView (NCBI)RXFP4
Genatlas (Paris)RXFP4
SOURCE (Princeton)RXFP4
Genetics Home Reference (NIH)RXFP4
Genomic and cartography
GoldenPath hg38 (UCSC)RXFP4  -     chr1:155941638-155943086 +  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)RXFP4  -     1q22   [Description]    (hg19-Feb_2009)
GoldenPathRXFP4 - 1q22 [CytoView hg19]  RXFP4 - 1q22 [CytoView hg38]
ImmunoBaseENSG00000173080
Genome Data Viewer NCBIRXFP4 [Mapview hg19]  
OMIM609043   
Gene and transcription
Genbank (Entrez)AY170824 AY288415 AY394502 BC101507 BC101509
RefSeq transcript (Entrez)NM_181885
Consensus coding sequences : CCDS (NCBI)RXFP4
Gene ExpressionRXFP4 [ NCBI-GEO ]   RXFP4 [ EBI - ARRAY_EXPRESS ]   RXFP4 [ SEEK ]   RXFP4 [ MEM ]
Gene Expression Viewer (FireBrowse)RXFP4 [ Firebrowse - Broad ]
GenevisibleExpression of RXFP4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339403
GTEX Portal (Tissue expression)RXFP4
Human Protein AtlasENSG00000173080-RXFP4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TDU9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TDU9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TDU9
PhosPhoSitePlusQ8TDU9
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)ATII_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)RXFP4
SuperfamilyQ8TDU9
AlphaFold pdb e-kbQ8TDU9   
Human Protein Atlas [tissue]ENSG00000173080-RXFP4 [tissue]
HPRD16421
Protein Interaction databases
DIP (DOE-UCLA)Q8TDU9
IntAct (EBI)Q8TDU9
BioGRIDRXFP4
STRING (EMBL)RXFP4
ZODIACRXFP4
Ontologies - Pathways
QuickGOQ8TDU9
Ontology : AmiGOprotein binding  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  G protein-coupled peptide receptor activity  positive regulation of feeding behavior  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of plasma membrane  G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  G protein-coupled peptide receptor activity  positive regulation of feeding behavior  
NDEx NetworkRXFP4
Atlas of Cancer Signalling NetworkRXFP4
Wikipedia pathwaysRXFP4
Orthology - Evolution
OrthoDB339403
GeneTree (enSembl)ENSG00000173080
Phylogenetic Trees/Animal Genes : TreeFamRXFP4
Homologs : HomoloGeneRXFP4
Homology/Alignments : Family Browser (UCSC)RXFP4
Gene fusions - Rearrangements
Fusion : QuiverRXFP4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerRXFP4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)RXFP4
dbVarRXFP4
ClinVarRXFP4
MonarchRXFP4
1000_GenomesRXFP4 
Exome Variant ServerRXFP4
GNOMAD BrowserENSG00000173080
Varsome BrowserRXFP4
ACMGRXFP4 variants
VarityQ8TDU9
Genomic Variants (DGV)RXFP4 [DGVbeta]
DECIPHERRXFP4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisRXFP4 
Mutations
ICGC Data PortalRXFP4 
TCGA Data PortalRXFP4 
Broad Tumor PortalRXFP4
OASIS PortalRXFP4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICRXFP4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DRXFP4
Mutations and Diseases : HGMDRXFP4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaRXFP4
DgiDB (Drug Gene Interaction Database)RXFP4
DoCM (Curated mutations)RXFP4
CIViC (Clinical Interpretations of Variants in Cancer)RXFP4
Cancer3DRXFP4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609043   
Orphanet
DisGeNETRXFP4
MedgenRXFP4
Genetic Testing Registry RXFP4
NextProtQ8TDU9 [Medical]
GENETestsRXFP4
Target ValidationRXFP4
Huge Navigator RXFP4 [HugePedia]
ClinGenRXFP4
Clinical trials, drugs, therapy
MyCancerGenomeRXFP4
Protein Interactions : CTDRXFP4
Pharm GKB GenePA28848
PharosQ8TDU9
Clinical trialRXFP4
Miscellaneous
canSAR (ICR)RXFP4
HarmonizomeRXFP4
DataMed IndexRXFP4
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXRXFP4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 16:19:41 CEST 2021

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