SAFB2 (scaffold attachment factor B2)

2007-02-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 9667
MIM: 608066
HGNC: 21605
Ensembl: ENSG00000130254

Variants:

dbSNP: 9667
ClinVar: 9667
TCGA: ENSG00000130254
COSMIC: SAFB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130254ENST00000252542Q14151
ENSG00000130254ENST00000590262K7ERX3
ENSG00000130254ENST00000591120Q14151
ENSG00000130254ENST00000591123K7EQU4

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
145870242003Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?25
191374252010Low SAFB levels are associated with worse outcome in breast cancer patients.13
199010292010SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.12
225661852012Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα.6
190772932008No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p.5
196741062009The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2.4
262736162015Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells.1

Citation

Dessen P

SAFB2 (scaffold attachment factor B2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46306/safb2