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SAP18 (Sin3A associated protein 18)

Identity

Alias_namessin3A-associated protein
Alias_symbol (synonym)SAP18p
2HOR0202
MGC27131
Other aliasSAP18P
HGNC (Hugo) SAP18
LocusID (NCBI) 10284
Atlas_Id 42201
Location 13q12.11  [Link to chromosome band 13q12]
Location_base_pair Starts at 21140514 and ends at 21149085 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SAP18 (13q12.11) / ILF2 (1q21.3)SAP18 (13q12.11) / SAP18 (13q12.11)SAP18 (13q12.11) / USP54 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SAP18   10530
Cards
Entrez_Gene (NCBI)SAP18  10284  Sin3A associated protein 18
Aliases2HOR0202; SAP18P
GeneCards (Weizmann)SAP18
Ensembl hg19 (Hinxton)ENSG00000150459 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000150459 [Gene_View]  chr13:21140514-21149085 [Contig_View]  SAP18 [Vega]
ICGC DataPortalENSG00000150459
TCGA cBioPortalSAP18
AceView (NCBI)SAP18
Genatlas (Paris)SAP18
WikiGenes10284
SOURCE (Princeton)SAP18
Genetics Home Reference (NIH)SAP18
Genomic and cartography
GoldenPath hg38 (UCSC)SAP18  -     chr13:21140514-21149085 +  13q12.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SAP18  -     13q12.11   [Description]    (hg19-Feb_2009)
EnsemblSAP18 - 13q12.11 [CytoView hg19]  SAP18 - 13q12.11 [CytoView hg38]
Mapping of homologs : NCBISAP18 [Mapview hg19]  SAP18 [Mapview hg38]
OMIM602949   
Gene and transcription
Genbank (Entrez)AF153608 AK311748 AY550970 BC030836 BU618473
RefSeq transcript (Entrez)NM_005870
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SAP18
Cluster EST : UnigeneHs.524899 [ NCBI ]
CGAP (NCI)Hs.524899
Alternative Splicing GalleryENSG00000150459
Gene ExpressionSAP18 [ NCBI-GEO ]   SAP18 [ EBI - ARRAY_EXPRESS ]   SAP18 [ SEEK ]   SAP18 [ MEM ]
Gene Expression Viewer (FireBrowse)SAP18 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10284
GTEX Portal (Tissue expression)SAP18
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00422   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00422  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00422
Splice isoforms : SwissVarO00422
PhosPhoSitePlusO00422
Domains : Interpro (EBI)Hist_deAcase_cplx_SAP18    SAP18   
Domain families : Pfam (Sanger)SAP18 (PF06487)   
Domain families : Pfam (NCBI)pfam06487   
Conserved Domain (NCBI)SAP18
DMDM Disease mutations10284
Blocks (Seattle)SAP18
PDB (SRS)2HDE   
PDB (PDBSum)2HDE   
PDB (IMB)2HDE   
PDB (RSDB)2HDE   
Structural Biology KnowledgeBase2HDE   
SCOP (Structural Classification of Proteins)2HDE   
CATH (Classification of proteins structures)2HDE   
SuperfamilyO00422
Human Protein AtlasENSG00000150459
Peptide AtlasO00422
HPRD04256
IPIIPI00011698   IPI00927280   
Protein Interaction databases
DIP (DOE-UCLA)O00422
IntAct (EBI)O00422
FunCoupENSG00000150459
BioGRIDSAP18
STRING (EMBL)SAP18
ZODIACSAP18
Ontologies - Pathways
QuickGOO00422
Ontology : AmiGOhistone deacetylase complex  regulation of alternative mRNA splicing, via spliceosome  regulation of alternative mRNA splicing, via spliceosome  transcription corepressor activity  RNA binding  histone deacetylase activity  protein binding  nucleoplasm  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  mRNA processing  RNA splicing  histone deacetylation  nuclear body  nuclear speck  exon-exon junction complex  positive regulation of apoptotic process  negative regulation of mRNA splicing, via spliceosome  ASAP complex  negative regulation of nucleic acid-templated transcription  
Ontology : EGO-EBIhistone deacetylase complex  regulation of alternative mRNA splicing, via spliceosome  regulation of alternative mRNA splicing, via spliceosome  transcription corepressor activity  RNA binding  histone deacetylase activity  protein binding  nucleoplasm  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  mRNA processing  RNA splicing  histone deacetylation  nuclear body  nuclear speck  exon-exon junction complex  positive regulation of apoptotic process  negative regulation of mRNA splicing, via spliceosome  ASAP complex  negative regulation of nucleic acid-templated transcription  
Pathways : KEGGRNA transport    mRNA surveillance pathway   
NDEx NetworkSAP18
Atlas of Cancer Signalling NetworkSAP18
Wikipedia pathwaysSAP18
Orthology - Evolution
OrthoDB10284
GeneTree (enSembl)ENSG00000150459
Phylogenetic Trees/Animal Genes : TreeFamSAP18
HOVERGENO00422
HOGENOMO00422
Homologs : HomoloGeneSAP18
Homology/Alignments : Family Browser (UCSC)SAP18
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSAP18 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SAP18
dbVarSAP18
ClinVarSAP18
1000_GenomesSAP18 
Exome Variant ServerSAP18
ExAC (Exome Aggregation Consortium)SAP18 (select the gene name)
Genetic variants : HAPMAP10284
Genomic Variants (DGV)SAP18 [DGVbeta]
DECIPHERSAP18 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSAP18 
Mutations
ICGC Data PortalSAP18 
TCGA Data PortalSAP18 
Broad Tumor PortalSAP18
OASIS PortalSAP18 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSAP18  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSAP18
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SAP18
DgiDB (Drug Gene Interaction Database)SAP18
DoCM (Curated mutations)SAP18 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SAP18 (select a term)
intoGenSAP18
Cancer3DSAP18(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602949   
Orphanet
MedgenSAP18
Genetic Testing Registry SAP18
NextProtO00422 [Medical]
TSGene10284
GENETestsSAP18
Target ValidationSAP18
Huge Navigator SAP18 [HugePedia]
snp3D : Map Gene to Disease10284
BioCentury BCIQSAP18
ClinGenSAP18
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10284
Chemical/Pharm GKB GenePA34940
Clinical trialSAP18
Miscellaneous
canSAR (ICR)SAP18 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSAP18
EVEXSAP18
GoPubMedSAP18
iHOPSAP18
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:13:42 CEST 2017

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