SAPCD2 (suppressor APC domain containing 2)

2013-08-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
C9orf140,p42.3

Other Information

Locus ID:

NCBI: 89958
MIM: 612057
HGNC: 28055
Ensembl: ENSG00000186193

Variants:

dbSNP: 89958
ClinVar: 89958
TCGA: ENSG00000186193
COSMIC: SAPCD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186193ENST00000409687Q86UD0

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
219987102011MiR-29a inhibits cell proliferation and induces cell cycle arrest through the downregulation of p42.3 in human gastric cancer.43
232281052012p42.3 gene expression in gastric cancer cell and its protein regulatory network analysis.7
267664422016SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex.7
235760222013p42.3: a promising biomarker for the progression and prognosis of human colorectal cancer.6
237048242013Overexpression of p42.3 promotes cell growth and tumorigenicity in hepatocellular carcinoma.6
231928432014Cell cycle-dependent expression of p42.3 promotes mitotic progression in malignant transformed cells.5
246080432014Role of C9orf140 in the promotion of colorectal cancer progression and mechanisms of its upregulation via activation of STAT5, β-catenin and EZH2.5
261064392015Optimization and Corroboration of the Regulatory Pathway of p42.3 Protein in the Pathogenesis of Gastric Carcinoma.3
263162592015Positive relationship between p42.3 gene and inflammation in chronic non-atrophic gastritis.3
249277512014Differential expression of p42.3 in low- and high-grade gliomas.2

Citation

Dessen P

SAPCD2 (suppressor APC domain containing 2)

Atlas Genet Cytogenet Oncol Haematol. 2013-08-01

Online version: http://atlasgeneticsoncology.org/gene/53738/sapcd2