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SAR1A (secretion associated Ras related GTPase 1A)

Identity

Alias (NCBI)SAR1
SARA1
Sara
masra2
HGNC (Hugo) SAR1A
HGNC Alias symbSAR1
Sara
HGNC Previous nameSARA1
HGNC Previous nameSAR1a gene homolog (S. cerevisiae) 1
 SAR1a gene homolog 1 (S. cerevisiae)
 SAR1 homolog A (S. cerevisiae)
 secretion associated, Ras related GTPase 1A
LocusID (NCBI) 56681
Atlas_Id 72979
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 70147289 and ends at 70170514 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SAR1A (10q22.1) / NDC1 (1p32.3)SAR1A (10q22.1) / NPFFR1 (10q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SAR1A   10534
Cards
Entrez_Gene (NCBI)SAR1A    secretion associated Ras related GTPase 1A
AliasesSAR1; SARA1; Sara; masra2
GeneCards (Weizmann)SAR1A
Ensembl hg19 (Hinxton)ENSG00000079332 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000079332 [Gene_View]  ENSG00000079332 [Sequence]  chr10:70147289-70170514 [Contig_View]  SAR1A [Vega]
ICGC DataPortalENSG00000079332
TCGA cBioPortalSAR1A
AceView (NCBI)SAR1A
Genatlas (Paris)SAR1A
SOURCE (Princeton)SAR1A
Genetics Home Reference (NIH)SAR1A
Genomic and cartography
GoldenPath hg38 (UCSC)SAR1A  -     chr10:70147289-70170514 -  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SAR1A  -     10q22.1   [Description]    (hg19-Feb_2009)
GoldenPathSAR1A - 10q22.1 [CytoView hg19]  SAR1A - 10q22.1 [CytoView hg38]
ImmunoBaseENSG00000079332
Genome Data Viewer NCBISAR1A [Mapview hg19]  
OMIM607691   
Gene and transcription
Genbank (Entrez)AF086166 AF087897 AF217959 AF261717 AF274026
RefSeq transcript (Entrez)NM_001142648 NM_020150
Consensus coding sequences : CCDS (NCBI)SAR1A
Gene ExpressionSAR1A [ NCBI-GEO ]   SAR1A [ EBI - ARRAY_EXPRESS ]   SAR1A [ SEEK ]   SAR1A [ MEM ]
Gene Expression Viewer (FireBrowse)SAR1A [ Firebrowse - Broad ]
GenevisibleExpression of SAR1A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56681
GTEX Portal (Tissue expression)SAR1A
Human Protein AtlasENSG00000079332-SAR1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR31   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NR31  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NR31
PhosPhoSitePlusQ9NR31
Domaine pattern : Prosite (Expaxy)SAR1 (PS51422)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF/SAR    Small_GTPase_SAR1   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)SAR1A
PDB (RSDB)2GAO   
PDB Europe2GAO   
PDB (PDBSum)2GAO   
PDB (IMB)2GAO   
Structural Biology KnowledgeBase2GAO   
SCOP (Structural Classification of Proteins)2GAO   
CATH (Classification of proteins structures)2GAO   
SuperfamilyQ9NR31
AlphaFold pdb e-kbQ9NR31   
Human Protein Atlas [tissue]ENSG00000079332-SAR1A [tissue]
HPRD07608
Protein Interaction databases
DIP (DOE-UCLA)Q9NR31
IntAct (EBI)Q9NR31
BioGRIDSAR1A
STRING (EMBL)SAR1A
ZODIACSAR1A
Ontologies - Pathways
QuickGOQ9NR31
Ontology : AmiGOregulation of COPII vesicle coating  GTPase activity  protein binding  GTP binding  Golgi apparatus  intracellular protein transport  endoplasmic reticulum to Golgi vesicle-mediated transport  vesicle organization  COPII vesicle coat  COPII vesicle coat  membrane organization  positive regulation of protein exit from endoplasmic reticulum  endoplasmic reticulum exit site  COPII-coated vesicle cargo loading  
Ontology : EGO-EBIregulation of COPII vesicle coating  GTPase activity  protein binding  GTP binding  Golgi apparatus  intracellular protein transport  endoplasmic reticulum to Golgi vesicle-mediated transport  vesicle organization  COPII vesicle coat  COPII vesicle coat  membrane organization  positive regulation of protein exit from endoplasmic reticulum  endoplasmic reticulum exit site  COPII-coated vesicle cargo loading  
NDEx NetworkSAR1A
Atlas of Cancer Signalling NetworkSAR1A
Wikipedia pathwaysSAR1A
Orthology - Evolution
OrthoDB56681
GeneTree (enSembl)ENSG00000079332
Phylogenetic Trees/Animal Genes : TreeFamSAR1A
Homologs : HomoloGeneSAR1A
Homology/Alignments : Family Browser (UCSC)SAR1A
Gene fusions - Rearrangements
Fusion : QuiverSAR1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSAR1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SAR1A
dbVarSAR1A
ClinVarSAR1A
MonarchSAR1A
1000_GenomesSAR1A 
Exome Variant ServerSAR1A
GNOMAD BrowserENSG00000079332
Varsome BrowserSAR1A
ACMGSAR1A variants
VarityQ9NR31
Genomic Variants (DGV)SAR1A [DGVbeta]
DECIPHERSAR1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSAR1A 
Mutations
ICGC Data PortalSAR1A 
TCGA Data PortalSAR1A 
Broad Tumor PortalSAR1A
OASIS PortalSAR1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSAR1A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSAR1A
Mutations and Diseases : HGMDSAR1A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSAR1A
DgiDB (Drug Gene Interaction Database)SAR1A
DoCM (Curated mutations)SAR1A
CIViC (Clinical Interpretations of Variants in Cancer)SAR1A
Cancer3DSAR1A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607691   
Orphanet
DisGeNETSAR1A
MedgenSAR1A
Genetic Testing Registry SAR1A
NextProtQ9NR31 [Medical]
GENETestsSAR1A
Target ValidationSAR1A
Huge Navigator SAR1A [HugePedia]
ClinGenSAR1A
Clinical trials, drugs, therapy
MyCancerGenomeSAR1A
Protein Interactions : CTDSAR1A
Pharm GKB GenePA34942
PharosQ9NR31
Clinical trialSAR1A
Miscellaneous
canSAR (ICR)SAR1A
HarmonizomeSAR1A
DataMed IndexSAR1A
Probes
Litterature
PubMed76 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSAR1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:19:47 CEST 2021

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