Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SAR1B (secretion associated Ras related GTPase 1B)

Identity

Alias_namesSARA2
SAR1a gene homolog (S. cerevisiae) 2
SAR1a gene homolog 2 (S. cerevisiae)
SAR1 homolog B (S. cerevisiae)
secretion associated, Ras related GTPase 1B
Other aliasANDD
CMRD
GTBPB
HGNC (Hugo) SAR1B
LocusID (NCBI) 51128
Atlas_Id 56436
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 134601149 and ends at 134632843 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SAR1B (5q31.1) / KLF12 (13q22.1)SAR1B (5q31.1) / SAR1B (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SAR1B   10535
Cards
Entrez_Gene (NCBI)SAR1B  51128  secretion associated Ras related GTPase 1B
AliasesANDD; CMRD; GTBPB; SARA2
GeneCards (Weizmann)SAR1B
Ensembl hg19 (Hinxton)ENSG00000152700 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152700 [Gene_View]  chr5:134601149-134632843 [Contig_View]  SAR1B [Vega]
ICGC DataPortalENSG00000152700
TCGA cBioPortalSAR1B
AceView (NCBI)SAR1B
Genatlas (Paris)SAR1B
WikiGenes51128
SOURCE (Princeton)SAR1B
Genetics Home Reference (NIH)SAR1B
Genomic and cartography
GoldenPath hg38 (UCSC)SAR1B  -     chr5:134601149-134632843 -  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SAR1B  -     5q31.1   [Description]    (hg19-Feb_2009)
EnsemblSAR1B - 5q31.1 [CytoView hg19]  SAR1B - 5q31.1 [CytoView hg38]
Mapping of homologs : NCBISAR1B [Mapview hg19]  SAR1B [Mapview hg38]
OMIM246700   607690   
Gene and transcription
Genbank (Entrez)AF087850 AF092130 AK056821 AK223452 AL512710
RefSeq transcript (Entrez)NM_001033503 NM_016103
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SAR1B
Cluster EST : UnigeneHs.432984 [ NCBI ]
CGAP (NCI)Hs.432984
Alternative Splicing GalleryENSG00000152700
Gene ExpressionSAR1B [ NCBI-GEO ]   SAR1B [ EBI - ARRAY_EXPRESS ]   SAR1B [ SEEK ]   SAR1B [ MEM ]
Gene Expression Viewer (FireBrowse)SAR1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51128
GTEX Portal (Tissue expression)SAR1B
Human Protein AtlasENSG00000152700-SAR1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6B6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6B6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6B6
Splice isoforms : SwissVarQ9Y6B6
PhosPhoSitePlusQ9Y6B6
Domaine pattern : Prosite (Expaxy)SAR1 (PS51422)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF/SAR    Small_GTPase_SAR1   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)SAR1B
DMDM Disease mutations51128
Blocks (Seattle)SAR1B
SuperfamilyQ9Y6B6
Human Protein Atlas [tissue]ENSG00000152700-SAR1B [tissue]
Peptide AtlasQ9Y6B6
HPRD09647
IPIIPI00002149   IPI00967559   IPI00964410   IPI00964747   IPI00968137   IPI00966157   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6B6
IntAct (EBI)Q9Y6B6
FunCoupENSG00000152700
BioGRIDSAR1B
STRING (EMBL)SAR1B
ZODIACSAR1B
Ontologies - Pathways
QuickGOQ9Y6B6
Ontology : AmiGOantigen processing and presentation of peptide antigen via MHC class I  GTPase activity  GTP binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  ER to Golgi transport vesicle membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  Golgi cisterna membrane  metal ion binding  COPII vesicle coating  
Ontology : EGO-EBIantigen processing and presentation of peptide antigen via MHC class I  GTPase activity  GTP binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  ER to Golgi transport vesicle membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  Golgi cisterna membrane  metal ion binding  COPII vesicle coating  
Pathways : KEGGProtein processing in endoplasmic reticulum    Legionellosis   
NDEx NetworkSAR1B
Atlas of Cancer Signalling NetworkSAR1B
Wikipedia pathwaysSAR1B
Orthology - Evolution
OrthoDB51128
GeneTree (enSembl)ENSG00000152700
Phylogenetic Trees/Animal Genes : TreeFamSAR1B
HOVERGENQ9Y6B6
HOGENOMQ9Y6B6
Homologs : HomoloGeneSAR1B
Homology/Alignments : Family Browser (UCSC)SAR1B
Gene fusions - Rearrangements
Tumor Fusion PortalSAR1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSAR1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SAR1B
dbVarSAR1B
ClinVarSAR1B
1000_GenomesSAR1B 
Exome Variant ServerSAR1B
ExAC (Exome Aggregation Consortium)ENSG00000152700
GNOMAD BrowserENSG00000152700
Genetic variants : HAPMAP51128
Genomic Variants (DGV)SAR1B [DGVbeta]
DECIPHERSAR1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSAR1B 
Mutations
ICGC Data PortalSAR1B 
TCGA Data PortalSAR1B 
Broad Tumor PortalSAR1B
OASIS PortalSAR1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSAR1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSAR1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SAR1B
DgiDB (Drug Gene Interaction Database)SAR1B
DoCM (Curated mutations)SAR1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SAR1B (select a term)
intoGenSAR1B
Cancer3DSAR1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM246700    607690   
Orphanet998   
DisGeNETSAR1B
MedgenSAR1B
Genetic Testing Registry SAR1B
NextProtQ9Y6B6 [Medical]
TSGene51128
GENETestsSAR1B
Target ValidationSAR1B
Huge Navigator SAR1B [HugePedia]
snp3D : Map Gene to Disease51128
BioCentury BCIQSAR1B
ClinGenSAR1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51128
Chemical/Pharm GKB GenePA34943
Clinical trialSAR1B
Miscellaneous
canSAR (ICR)SAR1B (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSAR1B
EVEXSAR1B
GoPubMedSAR1B
iHOPSAR1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:33:29 CET 2017

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