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SAR1B (secretion associated Ras related GTPase 1B)

Identity

Alias (NCBI)ANDD
CMRD
GTBPB
SARA2
HGNC (Hugo) SAR1B
HGNC Previous nameSARA2
HGNC Previous nameSAR1a gene homolog (S. cerevisiae) 2
 SAR1a gene homolog 2 (S. cerevisiae)
 SAR1 homolog B (S. cerevisiae)
 secretion associated, Ras related GTPase 1B
LocusID (NCBI) 51128
Atlas_Id 56436
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 134601149 and ends at 134632828 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SAR1B (5q31.1) / KLF12 (13q22.1)SAR1B (5q31.1) / SAR1B (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SAR1B   10535
Cards
Entrez_Gene (NCBI)SAR1B    secretion associated Ras related GTPase 1B
AliasesANDD; CMRD; GTBPB; SARA2
GeneCards (Weizmann)SAR1B
Ensembl hg19 (Hinxton)ENSG00000152700 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152700 [Gene_View]  ENSG00000152700 [Sequence]  chr5:134601149-134632828 [Contig_View]  SAR1B [Vega]
ICGC DataPortalENSG00000152700
TCGA cBioPortalSAR1B
AceView (NCBI)SAR1B
Genatlas (Paris)SAR1B
SOURCE (Princeton)SAR1B
Genetics Home Reference (NIH)SAR1B
Genomic and cartography
GoldenPath hg38 (UCSC)SAR1B  -     chr5:134601149-134632828 -  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SAR1B  -     5q31.1   [Description]    (hg19-Feb_2009)
GoldenPathSAR1B - 5q31.1 [CytoView hg19]  SAR1B - 5q31.1 [CytoView hg38]
ImmunoBaseENSG00000152700
Genome Data Viewer NCBISAR1B [Mapview hg19]  
OMIM246700   607690   
Gene and transcription
Genbank (Entrez)AF087850 AF092130 AK056821 AK223452 AL512710
RefSeq transcript (Entrez)NM_001033503 NM_016103
Consensus coding sequences : CCDS (NCBI)SAR1B
Gene ExpressionSAR1B [ NCBI-GEO ]   SAR1B [ EBI - ARRAY_EXPRESS ]   SAR1B [ SEEK ]   SAR1B [ MEM ]
Gene Expression Viewer (FireBrowse)SAR1B [ Firebrowse - Broad ]
GenevisibleExpression of SAR1B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51128
GTEX Portal (Tissue expression)SAR1B
Human Protein AtlasENSG00000152700-SAR1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6B6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6B6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6B6
PhosPhoSitePlusQ9Y6B6
Domaine pattern : Prosite (Expaxy)SAR1 (PS51422)   
Domains : Interpro (EBI)P-loop_NTPase    Small_GTP-bd_dom    Small_GTPase_ARF/SAR    Small_GTPase_SAR1   
Domain families : Pfam (Sanger)Arf (PF00025)   
Domain families : Pfam (NCBI)pfam00025   
Conserved Domain (NCBI)SAR1B
SuperfamilyQ9Y6B6
AlphaFold pdb e-kbQ9Y6B6   
Human Protein Atlas [tissue]ENSG00000152700-SAR1B [tissue]
HPRD09647
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6B6
IntAct (EBI)Q9Y6B6
BioGRIDSAR1B
STRING (EMBL)SAR1B
ZODIACSAR1B
Ontologies - Pathways
QuickGOQ9Y6B6
Ontology : AmiGOantigen processing and presentation of peptide antigen via MHC class I  regulation of COPII vesicle coating  GTPase activity  protein binding  GTP binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  endoplasmic reticulum to Golgi vesicle-mediated transport  endoplasmic reticulum to Golgi vesicle-mediated transport  ER to Golgi transport vesicle membrane  vesicle organization  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPII vesicle coat  Golgi cisterna membrane  metal ion binding  COPII vesicle coating  membrane organization  positive regulation of protein exit from endoplasmic reticulum  endoplasmic reticulum exit site  
Ontology : EGO-EBIantigen processing and presentation of peptide antigen via MHC class I  regulation of COPII vesicle coating  GTPase activity  protein binding  GTP binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  endoplasmic reticulum to Golgi vesicle-mediated transport  endoplasmic reticulum to Golgi vesicle-mediated transport  ER to Golgi transport vesicle membrane  vesicle organization  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPII vesicle coat  Golgi cisterna membrane  metal ion binding  COPII vesicle coating  membrane organization  positive regulation of protein exit from endoplasmic reticulum  endoplasmic reticulum exit site  
Pathways : KEGGProtein processing in endoplasmic reticulum    Legionellosis   
NDEx NetworkSAR1B
Atlas of Cancer Signalling NetworkSAR1B
Wikipedia pathwaysSAR1B
Orthology - Evolution
OrthoDB51128
GeneTree (enSembl)ENSG00000152700
Phylogenetic Trees/Animal Genes : TreeFamSAR1B
Homologs : HomoloGeneSAR1B
Homology/Alignments : Family Browser (UCSC)SAR1B
Gene fusions - Rearrangements
Fusion : QuiverSAR1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSAR1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SAR1B
dbVarSAR1B
ClinVarSAR1B
MonarchSAR1B
1000_GenomesSAR1B 
Exome Variant ServerSAR1B
GNOMAD BrowserENSG00000152700
Varsome BrowserSAR1B
ACMGSAR1B variants
VarityQ9Y6B6
Genomic Variants (DGV)SAR1B [DGVbeta]
DECIPHERSAR1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSAR1B 
Mutations
ICGC Data PortalSAR1B 
TCGA Data PortalSAR1B 
Broad Tumor PortalSAR1B
OASIS PortalSAR1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSAR1B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSAR1B
Mutations and Diseases : HGMDSAR1B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSAR1B
DgiDB (Drug Gene Interaction Database)SAR1B
DoCM (Curated mutations)SAR1B
CIViC (Clinical Interpretations of Variants in Cancer)SAR1B
Cancer3DSAR1B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM246700    607690   
Orphanet998   
DisGeNETSAR1B
MedgenSAR1B
Genetic Testing Registry SAR1B
NextProtQ9Y6B6 [Medical]
GENETestsSAR1B
Target ValidationSAR1B
Huge Navigator SAR1B [HugePedia]
ClinGenSAR1B
Clinical trials, drugs, therapy
MyCancerGenomeSAR1B
Protein Interactions : CTDSAR1B
Pharm GKB GenePA34943
PharosQ9Y6B6
Clinical trialSAR1B
Miscellaneous
canSAR (ICR)SAR1B
HarmonizomeSAR1B
DataMed IndexSAR1B
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSAR1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:30:04 CEST 2021

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