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SARAF (store-operated calcium entry-associated regulatory factor)

Identity

Alias_namesTMEM66
transmembrane protein 66
Alias_symbol (synonym)MGC8721
Other aliasFOAP-7
HSPC035
XTP3
HGNC (Hugo) SARAF
LocusID (NCBI) 51669
Atlas_Id 54028
Location 8p12  [Link to chromosome band 8p12]
Location_base_pair Starts at 29920528 and ends at 29940724 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EXTL3 (8p21.1) / SARAF (8p12)SARAF (8p12) / MSRB3 (12q14.3)SARAF (8p12) / TNKS (8p23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SARAF   28789
Cards
Entrez_Gene (NCBI)SARAF  51669  store-operated calcium entry-associated regulatory factor
AliasesFOAP-7; HSPC035; TMEM66; XTP3
GeneCards (Weizmann)SARAF
Ensembl hg19 (Hinxton)ENSG00000133872 [Gene_View]  chr8:29920528-29940724 [Contig_View]  SARAF [Vega]
Ensembl hg38 (Hinxton)ENSG00000133872 [Gene_View]  chr8:29920528-29940724 [Contig_View]  SARAF [Vega]
ICGC DataPortalENSG00000133872
TCGA cBioPortalSARAF
AceView (NCBI)SARAF
Genatlas (Paris)SARAF
WikiGenes51669
SOURCE (Princeton)SARAF
Genetics Home Reference (NIH)SARAF
Genomic and cartography
GoldenPath hg19 (UCSC)SARAF  -     chr8:29920528-29940724 -  8p12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SARAF  -     8p12   [Description]    (hg38-Dec_2013)
EnsemblSARAF - 8p12 [CytoView hg19]  SARAF - 8p12 [CytoView hg38]
Mapping of homologs : NCBISARAF [Mapview hg19]  SARAF [Mapview hg38]
OMIM614768   
Gene and transcription
Genbank (Entrez)AB028926 AF078855 AF100748 AF490252 AK025927
RefSeq transcript (Entrez)NM_001284239 NM_016127
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)SARAF
Cluster EST : UnigeneHs.521487 [ NCBI ]
CGAP (NCI)Hs.521487
Alternative Splicing GalleryENSG00000133872
Gene ExpressionSARAF [ NCBI-GEO ]   SARAF [ EBI - ARRAY_EXPRESS ]   SARAF [ SEEK ]   SARAF [ MEM ]
Gene Expression Viewer (FireBrowse)SARAF [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51669
GTEX Portal (Tissue expression)SARAF
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96BY9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96BY9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96BY9
Splice isoforms : SwissVarQ96BY9
PhosPhoSitePlusQ96BY9
Domains : Interpro (EBI)SARAF   
Domain families : Pfam (Sanger)SARAF (PF06682)   
Domain families : Pfam (NCBI)pfam06682   
Conserved Domain (NCBI)SARAF
DMDM Disease mutations51669
Blocks (Seattle)SARAF
SuperfamilyQ96BY9
Human Protein AtlasENSG00000133872
Peptide AtlasQ96BY9
HPRD08651
IPIIPI00604763   IPI00791617   IPI00983427   IPI01009323   IPI00984126   IPI00974379   IPI00976718   IPI00975718   IPI00974198   IPI00977615   IPI00792180   
Protein Interaction databases
DIP (DOE-UCLA)Q96BY9
IntAct (EBI)Q96BY9
FunCoupENSG00000133872
BioGRIDSARAF
STRING (EMBL)SARAF
ZODIACSARAF
Ontologies - Pathways
QuickGOQ96BY9
Ontology : AmiGOprotein binding  calcium ion transport  integral component of endoplasmic reticulum membrane  regulation of store-operated calcium entry  
Ontology : EGO-EBIprotein binding  calcium ion transport  integral component of endoplasmic reticulum membrane  regulation of store-operated calcium entry  
NDEx NetworkSARAF
Atlas of Cancer Signalling NetworkSARAF
Wikipedia pathwaysSARAF
Orthology - Evolution
OrthoDB51669
GeneTree (enSembl)ENSG00000133872
Phylogenetic Trees/Animal Genes : TreeFamSARAF
HOVERGENQ96BY9
HOGENOMQ96BY9
Homologs : HomoloGeneSARAF
Homology/Alignments : Family Browser (UCSC)SARAF
Gene fusions - Rearrangements
Fusion : MitelmanEXTL3/SARAF [8p21.1/8p12]  [t(8;8)(p12;p21)]  
Fusion : MitelmanSARAF/MSRB3 [8p12/12q14.3]  [t(8;12)(p12;q14)]  
Fusion : MitelmanSARAF/TNKS [8p12/8p23.1]  [t(8;8)(p12;p23)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSARAF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SARAF
dbVarSARAF
ClinVarSARAF
1000_GenomesSARAF 
Exome Variant ServerSARAF
ExAC (Exome Aggregation Consortium)SARAF (select the gene name)
Genetic variants : HAPMAP51669
Genomic Variants (DGV)SARAF [DGVbeta]
DECIPHER (Syndromes)8:29920528-29940724  ENSG00000133872
CONAN: Copy Number AnalysisSARAF 
Mutations
ICGC Data PortalSARAF 
TCGA Data PortalSARAF 
Broad Tumor PortalSARAF
OASIS PortalSARAF [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSARAF
BioMutasearch SARAF
DgiDB (Drug Gene Interaction Database)SARAF
DoCM (Curated mutations)SARAF (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SARAF (select a term)
intoGenSARAF
Cancer3DSARAF(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614768   
Orphanet
MedgenSARAF
Genetic Testing Registry SARAF
NextProtQ96BY9 [Medical]
TSGene51669
GENETestsSARAF
Huge Navigator SARAF [HugePedia]
snp3D : Map Gene to Disease51669
BioCentury BCIQSARAF
ClinGenSARAF
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51669
Chemical/Pharm GKB GenePA142670779
Clinical trialSARAF
Miscellaneous
canSAR (ICR)SARAF (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSARAF
EVEXSARAF
GoPubMedSARAF
iHOPSARAF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:18:21 CEST 2017

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