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SARS (seryl-tRNA synthetase)

Identity

Alias_symbol (synonym)SERS
Other aliasSERRS
HGNC (Hugo) SARS
LocusID (NCBI) 6301
Atlas_Id 72982
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 109213893 and ends at 109238182 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CCDC171 (9p22.3) / SARS (1p13.3)CELSR2 (1p13.3) / SARS (1p13.3)GNAI3 (1p13.3) / SARS (1p13.3)
POU5F1 (6p21.33) / SARS (1p13.3)PPDPF (20q13.33) / SARS (1p13.3)SARS (1p13.3) / COX6A1 (12q24.31)
SARS (1p13.3) / KIAA1324 (1p13.3)SARS (1p13.3) / MVD (16q24.3)CELSR2 SARS
GNAI3 SARS

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SARS   10537
Cards
Entrez_Gene (NCBI)SARS  6301  seryl-tRNA synthetase
AliasesSERRS; SERS
GeneCards (Weizmann)SARS
Ensembl hg19 (Hinxton)ENSG00000031698 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000031698 [Gene_View]  chr1:109213893-109238182 [Contig_View]  SARS [Vega]
ICGC DataPortalENSG00000031698
TCGA cBioPortalSARS
AceView (NCBI)SARS
Genatlas (Paris)SARS
WikiGenes6301
SOURCE (Princeton)SARS
Genetics Home Reference (NIH)SARS
Genomic and cartography
GoldenPath hg38 (UCSC)SARS  -     chr1:109213893-109238182 +  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SARS  -     1p13.3   [Description]    (hg19-Feb_2009)
EnsemblSARS - 1p13.3 [CytoView hg19]  SARS - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBISARS [Mapview hg19]  SARS [Mapview hg38]
OMIM607529   
Gene and transcription
Genbank (Entrez)AK022339 AK093718 AK222677 AK312771 BC000716
RefSeq transcript (Entrez)NM_001330669 NM_006513
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SARS
Cluster EST : UnigeneHs.531176 [ NCBI ]
CGAP (NCI)Hs.531176
Alternative Splicing GalleryENSG00000031698
Gene ExpressionSARS [ NCBI-GEO ]   SARS [ EBI - ARRAY_EXPRESS ]   SARS [ SEEK ]   SARS [ MEM ]
Gene Expression Viewer (FireBrowse)SARS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6301
GTEX Portal (Tissue expression)SARS
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49591   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49591  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49591
Splice isoforms : SwissVarP49591
Catalytic activity : Enzyme6.1.1.11 [ Enzyme-Expasy ]   6.1.1.116.1.1.11 [ IntEnz-EBI ]   6.1.1.11 [ BRENDA ]   6.1.1.11 [ KEGG ]   
PhosPhoSitePlusP49591
Domaine pattern : Prosite (Expaxy)AA_TRNA_LIGASE_II (PS50862)   
Domains : Interpro (EBI)aa-tRNA-synt_IIb    aa-tRNA-synth_II    Ser-tRNA-ligase_type_1    Ser-tRNA-synth_1_N    SerRS_core    tRNA-bd_arm   
Domain families : Pfam (Sanger)Seryl_tRNA_N (PF02403)    tRNA-synt_2b (PF00587)   
Domain families : Pfam (NCBI)pfam02403    pfam00587   
Conserved Domain (NCBI)SARS
DMDM Disease mutations6301
Blocks (Seattle)SARS
PDB (SRS)3VBB    4L87    4RQE    4RQF   
PDB (PDBSum)3VBB    4L87    4RQE    4RQF   
PDB (IMB)3VBB    4L87    4RQE    4RQF   
PDB (RSDB)3VBB    4L87    4RQE    4RQF   
Structural Biology KnowledgeBase3VBB    4L87    4RQE    4RQF   
SCOP (Structural Classification of Proteins)3VBB    4L87    4RQE    4RQF   
CATH (Classification of proteins structures)3VBB    4L87    4RQE    4RQF   
SuperfamilyP49591
Human Protein AtlasENSG00000031698
Peptide AtlasP49591
HPRD09605
IPIIPI00220637   IPI00514587   
Protein Interaction databases
DIP (DOE-UCLA)P49591
IntAct (EBI)P49591
FunCoupENSG00000031698
BioGRIDSARS
STRING (EMBL)SARS
ZODIACSARS
Ontologies - Pathways
QuickGOP49591
Ontology : AmiGORNA binding  serine-tRNA ligase activity  serine-tRNA ligase activity  ATP binding  cytoplasm  cytoplasm  cytosol  cytosol  translation  tRNA aminoacylation for protein translation  seryl-tRNA aminoacylation  seryl-tRNA aminoacylation  tRNA processing  selenocysteine metabolic process  extracellular exosome  selenocysteinyl-tRNA(Sec) biosynthetic process  selenocysteine-tRNA ligase activity  
Ontology : EGO-EBIRNA binding  serine-tRNA ligase activity  serine-tRNA ligase activity  ATP binding  cytoplasm  cytoplasm  cytosol  cytosol  translation  tRNA aminoacylation for protein translation  seryl-tRNA aminoacylation  seryl-tRNA aminoacylation  tRNA processing  selenocysteine metabolic process  extracellular exosome  selenocysteinyl-tRNA(Sec) biosynthetic process  selenocysteine-tRNA ligase activity  
Pathways : KEGGAminoacyl-tRNA biosynthesis   
NDEx NetworkSARS
Atlas of Cancer Signalling NetworkSARS
Wikipedia pathwaysSARS
Orthology - Evolution
OrthoDB6301
GeneTree (enSembl)ENSG00000031698
Phylogenetic Trees/Animal Genes : TreeFamSARS
HOVERGENP49591
HOGENOMP49591
Homologs : HomoloGeneSARS
Homology/Alignments : Family Browser (UCSC)SARS
Gene fusions - Rearrangements
Fusion: TCGACELSR2 SARS
Fusion: TCGAGNAI3 SARS
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSARS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SARS
dbVarSARS
ClinVarSARS
1000_GenomesSARS 
Exome Variant ServerSARS
ExAC (Exome Aggregation Consortium)SARS (select the gene name)
Genetic variants : HAPMAP6301
Genomic Variants (DGV)SARS [DGVbeta]
DECIPHERSARS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSARS 
Mutations
ICGC Data PortalSARS 
TCGA Data PortalSARS 
Broad Tumor PortalSARS
OASIS PortalSARS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSARS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSARS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SARS
DgiDB (Drug Gene Interaction Database)SARS
DoCM (Curated mutations)SARS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SARS (select a term)
intoGenSARS
Cancer3DSARS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607529   
Orphanet
MedgenSARS
Genetic Testing Registry SARS
NextProtP49591 [Medical]
TSGene6301
GENETestsSARS
Target ValidationSARS
Huge Navigator SARS [HugePedia]
snp3D : Map Gene to Disease6301
BioCentury BCIQSARS
ClinGenSARS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6301
Chemical/Pharm GKB GenePA34945
Clinical trialSARS
Miscellaneous
canSAR (ICR)SARS (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSARS
EVEXSARS
GoPubMedSARS
iHOPSARS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:37:11 CEST 2017

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