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SARS2 (seryl-tRNA synthetase 2, mitochondrial)

Identity

Alias_namesSARSM
serine-tRNA ligase, mitochondrial
seryl-tRNA synthetase 2
Alias_symbol (synonym)FLJ20450
mtSerRS
SerRSmt
SARS
SERS
SYS
Other aliasSerRS
HGNC (Hugo) SARS2
LocusID (NCBI) 54938
Atlas_Id 72983
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 38915264 and ends at 38930896 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SARS2 (19q13.2) / RBM33 (7q36.3)SARS2 (19q13.2) / SARS2 (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SARS2   17697
Cards
Entrez_Gene (NCBI)SARS2  54938  seryl-tRNA synthetase 2, mitochondrial
AliasesSARS; SARSM; SERS; SYS; 
SerRS; SerRSmt; mtSerRS
GeneCards (Weizmann)SARS2
Ensembl hg19 (Hinxton)ENSG00000104835 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104835 [Gene_View]  chr19:38915264-38930896 [Contig_View]  SARS2 [Vega]
ICGC DataPortalENSG00000104835
TCGA cBioPortalSARS2
AceView (NCBI)SARS2
Genatlas (Paris)SARS2
WikiGenes54938
SOURCE (Princeton)SARS2
Genetics Home Reference (NIH)SARS2
Genomic and cartography
GoldenPath hg38 (UCSC)SARS2  -     chr19:38915264-38930896 -  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SARS2  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblSARS2 - 19q13.2 [CytoView hg19]  SARS2 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBISARS2 [Mapview hg19]  SARS2 [Mapview hg38]
OMIM612804   613845   
Gene and transcription
Genbank (Entrez)AB029948 AK000457 AK098522 AK293414 AK296152
RefSeq transcript (Entrez)NM_001145901 NM_017827
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SARS2
Cluster EST : UnigeneHs.709416 [ NCBI ]
CGAP (NCI)Hs.709416
Alternative Splicing GalleryENSG00000104835
Gene ExpressionSARS2 [ NCBI-GEO ]   SARS2 [ EBI - ARRAY_EXPRESS ]   SARS2 [ SEEK ]   SARS2 [ MEM ]
Gene Expression Viewer (FireBrowse)SARS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54938
GTEX Portal (Tissue expression)SARS2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP81   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP81  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP81
Splice isoforms : SwissVarQ9NP81
Catalytic activity : Enzyme6.1.1.11 [ Enzyme-Expasy ]   6.1.1.116.1.1.11 [ IntEnz-EBI ]   6.1.1.11 [ BRENDA ]   6.1.1.11 [ KEGG ]   
PhosPhoSitePlusQ9NP81
Domaine pattern : Prosite (Expaxy)AA_TRNA_LIGASE_II (PS50862)   
Domains : Interpro (EBI)aa-tRNA-synt_IIb    aa-tRNA-synth_II    Ser-tRNA-ligase_type_1    Ser-tRNA-synth_1_N    SerRS_core    tRNA-bd_arm   
Domain families : Pfam (Sanger)tRNA-synt_2b (PF00587)   
Domain families : Pfam (NCBI)pfam00587   
Conserved Domain (NCBI)SARS2
DMDM Disease mutations54938
Blocks (Seattle)SARS2
SuperfamilyQ9NP81
Human Protein AtlasENSG00000104835
Peptide AtlasQ9NP81
HPRD15295
IPIIPI00328361   IPI00935536   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP81
IntAct (EBI)Q9NP81
FunCoupENSG00000104835
BioGRIDSARS2
STRING (EMBL)SARS2
ZODIACSARS2
Ontologies - Pathways
QuickGOQ9NP81
Ontology : AmiGORNA binding  serine-tRNA ligase activity  serine-tRNA ligase activity  serine-tRNA ligase activity  ATP binding  cytoplasm  mitochondrion  mitochondrial matrix  tRNA aminoacylation for protein translation  seryl-tRNA aminoacylation  seryl-tRNA aminoacylation  selenocysteinyl-tRNA(Sec) biosynthetic process  
Ontology : EGO-EBIRNA binding  serine-tRNA ligase activity  serine-tRNA ligase activity  serine-tRNA ligase activity  ATP binding  cytoplasm  mitochondrion  mitochondrial matrix  tRNA aminoacylation for protein translation  seryl-tRNA aminoacylation  seryl-tRNA aminoacylation  selenocysteinyl-tRNA(Sec) biosynthetic process  
Pathways : KEGGAminoacyl-tRNA biosynthesis   
NDEx NetworkSARS2
Atlas of Cancer Signalling NetworkSARS2
Wikipedia pathwaysSARS2
Orthology - Evolution
OrthoDB54938
GeneTree (enSembl)ENSG00000104835
Phylogenetic Trees/Animal Genes : TreeFamSARS2
HOVERGENQ9NP81
HOGENOMQ9NP81
Homologs : HomoloGeneSARS2
Homology/Alignments : Family Browser (UCSC)SARS2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSARS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SARS2
dbVarSARS2
ClinVarSARS2
1000_GenomesSARS2 
Exome Variant ServerSARS2
ExAC (Exome Aggregation Consortium)SARS2 (select the gene name)
Genetic variants : HAPMAP54938
Genomic Variants (DGV)SARS2 [DGVbeta]
DECIPHERSARS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSARS2 
Mutations
ICGC Data PortalSARS2 
TCGA Data PortalSARS2 
Broad Tumor PortalSARS2
OASIS PortalSARS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSARS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSARS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SARS2
DgiDB (Drug Gene Interaction Database)SARS2
DoCM (Curated mutations)SARS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SARS2 (select a term)
intoGenSARS2
Cancer3DSARS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612804    613845   
Orphanet22340   
MedgenSARS2
Genetic Testing Registry SARS2
NextProtQ9NP81 [Medical]
TSGene54938
GENETestsSARS2
Target ValidationSARS2
Huge Navigator SARS2 [HugePedia]
snp3D : Map Gene to Disease54938
BioCentury BCIQSARS2
ClinGenSARS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54938
Chemical/Pharm GKB GenePA134899753
Clinical trialSARS2
Miscellaneous
canSAR (ICR)SARS2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSARS2
EVEXSARS2
GoPubMedSARS2
iHOPSARS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:39:52 CEST 2017

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