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SBK2 (SH3 domain binding kinase family member 2)

Identity

Alias_namesSH3-binding domain kinase family, member 2
SH3 domain binding kinase family, member 2
Alias_symbol (synonym)SGK069
Other alias
HGNC (Hugo) SBK2
LocusID (NCBI) 646643
Atlas_Id 72991
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 55529733 and ends at 55536294 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SBK2   34416
Cards
Entrez_Gene (NCBI)SBK2  646643  SH3 domain binding kinase family member 2
AliasesSGK069
GeneCards (Weizmann)SBK2
Ensembl hg19 (Hinxton)ENSG00000187550 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187550 [Gene_View]  chr19:55529733-55536294 [Contig_View]  SBK2 [Vega]
ICGC DataPortalENSG00000187550
TCGA cBioPortalSBK2
AceView (NCBI)SBK2
Genatlas (Paris)SBK2
WikiGenes646643
SOURCE (Princeton)SBK2
Genetics Home Reference (NIH)SBK2
Genomic and cartography
GoldenPath hg38 (UCSC)SBK2  -     chr19:55529733-55536294 -  19q13.42   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SBK2  -     19q13.42   [Description]    (hg19-Feb_2009)
EnsemblSBK2 - 19q13.42 [CytoView hg19]  SBK2 - 19q13.42 [CytoView hg38]
Mapping of homologs : NCBISBK2 [Mapview hg19]  SBK2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001101401
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SBK2
Cluster EST : UnigeneHs.532676 [ NCBI ]
CGAP (NCI)Hs.532676
Alternative Splicing GalleryENSG00000187550
Gene ExpressionSBK2 [ NCBI-GEO ]   SBK2 [ EBI - ARRAY_EXPRESS ]   SBK2 [ SEEK ]   SBK2 [ MEM ]
Gene Expression Viewer (FireBrowse)SBK2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)646643
GTEX Portal (Tissue expression)SBK2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C263   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C263  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C263
Splice isoforms : SwissVarP0C263
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusP0C263
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)SBK2
DMDM Disease mutations646643
Blocks (Seattle)SBK2
SuperfamilyP0C263
Human Protein AtlasENSG00000187550
Peptide AtlasP0C263
IPIIPI00927133   
Protein Interaction databases
DIP (DOE-UCLA)P0C263
IntAct (EBI)P0C263
FunCoupENSG00000187550
BioGRIDSBK2
STRING (EMBL)SBK2
ZODIACSBK2
Ontologies - Pathways
QuickGOP0C263
Ontology : AmiGOmitotic cell cycle  signal transducer, downstream of receptor, with serine/threonine kinase activity  ATP binding  cytoplasm  signal transduction by protein phosphorylation  
Ontology : EGO-EBImitotic cell cycle  signal transducer, downstream of receptor, with serine/threonine kinase activity  ATP binding  cytoplasm  signal transduction by protein phosphorylation  
NDEx NetworkSBK2
Atlas of Cancer Signalling NetworkSBK2
Wikipedia pathwaysSBK2
Orthology - Evolution
OrthoDB646643
GeneTree (enSembl)ENSG00000187550
Phylogenetic Trees/Animal Genes : TreeFamSBK2
HOVERGENP0C263
HOGENOMP0C263
Homologs : HomoloGeneSBK2
Homology/Alignments : Family Browser (UCSC)SBK2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSBK2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SBK2
dbVarSBK2
ClinVarSBK2
1000_GenomesSBK2 
Exome Variant ServerSBK2
ExAC (Exome Aggregation Consortium)SBK2 (select the gene name)
Genetic variants : HAPMAP646643
Genomic Variants (DGV)SBK2 [DGVbeta]
DECIPHERSBK2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSBK2 
Mutations
ICGC Data PortalSBK2 
TCGA Data PortalSBK2 
Broad Tumor PortalSBK2
OASIS PortalSBK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSBK2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSBK2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SBK2
DgiDB (Drug Gene Interaction Database)SBK2
DoCM (Curated mutations)SBK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SBK2 (select a term)
intoGenSBK2
Cancer3DSBK2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSBK2
Genetic Testing Registry SBK2
NextProtP0C263 [Medical]
TSGene646643
GENETestsSBK2
Target ValidationSBK2
Huge Navigator SBK2 [HugePedia]
snp3D : Map Gene to Disease646643
BioCentury BCIQSBK2
ClinGenSBK2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD646643
Chemical/Pharm GKB GenePA164725571
Clinical trialSBK2
Miscellaneous
canSAR (ICR)SBK2 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSBK2
EVEXSBK2
GoPubMedSBK2
iHOPSBK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:39:54 CEST 2017

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