Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SCAF4 (SR-related CTD associated factor 4)

Identity

Alias (NCBI)SFRS15
SRA4
HGNC (Hugo) SCAF4
HGNC Alias symbKIAA1172
DKFZp434E098
SRA4
HGNC Previous nameSFRS15
HGNC Previous namesplicing factor, arginine/serine-rich 15
LocusID (NCBI) 57466
Atlas_Id 72995
Location 21q22.11  [Link to chromosome band 21q22]
Location_base_pair Starts at 31671000 and ends at 31732118 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SCAF4 (21q22.11) / CLEC2D (12p13.31)SCAF4 (21q22.11) / HLCS (21q22.13)SCAF4 (21q22.11) / SCAF4 (21q22.11)
SF3B2 (11q13.1) / SCAF4 (21q22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SCAF4   19304
Cards
Entrez_Gene (NCBI)SCAF4    SR-related CTD associated factor 4
AliasesSFRS15; SRA4
GeneCards (Weizmann)SCAF4
Ensembl hg19 (Hinxton)ENSG00000156304 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156304 [Gene_View]  ENSG00000156304 [Sequence]  chr21:31671000-31732118 [Contig_View]  SCAF4 [Vega]
ICGC DataPortalENSG00000156304
TCGA cBioPortalSCAF4
AceView (NCBI)SCAF4
Genatlas (Paris)SCAF4
SOURCE (Princeton)SCAF4
Genetics Home Reference (NIH)SCAF4
Genomic and cartography
GoldenPath hg38 (UCSC)SCAF4  -     chr21:31671000-31732118 -  21q22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCAF4  -     21q22.11   [Description]    (hg19-Feb_2009)
GoldenPathSCAF4 - 21q22.11 [CytoView hg19]  SCAF4 - 21q22.11 [CytoView hg38]
ImmunoBaseENSG00000156304
Genome Data Viewer NCBISCAF4 [Mapview hg19]  
OMIM616023   
Gene and transcription
Genbank (Entrez)AB032998 AF023142 AK025748 AK027017 AK057840
RefSeq transcript (Entrez)NM_001145444 NM_001145445 NM_020706
Consensus coding sequences : CCDS (NCBI)SCAF4
Gene ExpressionSCAF4 [ NCBI-GEO ]   SCAF4 [ EBI - ARRAY_EXPRESS ]   SCAF4 [ SEEK ]   SCAF4 [ MEM ]
Gene Expression Viewer (FireBrowse)SCAF4 [ Firebrowse - Broad ]
GenevisibleExpression of SCAF4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57466
GTEX Portal (Tissue expression)SCAF4
Human Protein AtlasENSG00000156304-SCAF4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95104   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95104  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95104
PhosPhoSitePlusO95104
Domaine pattern : Prosite (Expaxy)CID (PS51391)    RRM (PS50102)   
Domains : Interpro (EBI)CID_dom    ENTH_VHS    Nucleotide-bd_a/b_plait_sf    RBD_domain_sf    RRM_dom    SCAF4_RRM   
Domain families : Pfam (Sanger)CID (PF04818)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam04818    pfam00076   
Domain families : Smart (EMBL)RPR (SM00582)  RRM (SM00360)  
Conserved Domain (NCBI)SCAF4
SuperfamilyO95104
AlphaFold pdb e-kbO95104   
Human Protein Atlas [tissue]ENSG00000156304-SCAF4 [tissue]
HPRD11551
Protein Interaction databases
DIP (DOE-UCLA)O95104
IntAct (EBI)O95104
BioGRIDSCAF4
STRING (EMBL)SCAF4
ZODIACSCAF4
Ontologies - Pathways
QuickGOO95104
Ontology : AmiGORNA binding  RNA binding  nucleus  nucleoplasm  mRNA processing  protein C-terminus binding  RNA polymerase II C-terminal domain phosphoserine binding  negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled  
Ontology : EGO-EBIRNA binding  RNA binding  nucleus  nucleoplasm  mRNA processing  protein C-terminus binding  RNA polymerase II C-terminal domain phosphoserine binding  negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled  
NDEx NetworkSCAF4
Atlas of Cancer Signalling NetworkSCAF4
Wikipedia pathwaysSCAF4
Orthology - Evolution
OrthoDB57466
GeneTree (enSembl)ENSG00000156304
Phylogenetic Trees/Animal Genes : TreeFamSCAF4
Homologs : HomoloGeneSCAF4
Homology/Alignments : Family Browser (UCSC)SCAF4
Gene fusions - Rearrangements
Fusion : QuiverSCAF4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCAF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCAF4
dbVarSCAF4
ClinVarSCAF4
MonarchSCAF4
1000_GenomesSCAF4 
Exome Variant ServerSCAF4
GNOMAD BrowserENSG00000156304
Varsome BrowserSCAF4
ACMGSCAF4 variants
VarityO95104
Genomic Variants (DGV)SCAF4 [DGVbeta]
DECIPHERSCAF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCAF4 
Mutations
ICGC Data PortalSCAF4 
TCGA Data PortalSCAF4 
Broad Tumor PortalSCAF4
OASIS PortalSCAF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCAF4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSCAF4
Mutations and Diseases : HGMDSCAF4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSCAF4
DgiDB (Drug Gene Interaction Database)SCAF4
DoCM (Curated mutations)SCAF4
CIViC (Clinical Interpretations of Variants in Cancer)SCAF4
Cancer3DSCAF4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616023   
Orphanet
DisGeNETSCAF4
MedgenSCAF4
Genetic Testing Registry SCAF4
NextProtO95104 [Medical]
GENETestsSCAF4
Target ValidationSCAF4
Huge Navigator SCAF4 [HugePedia]
ClinGenSCAF4
Clinical trials, drugs, therapy
MyCancerGenomeSCAF4
Protein Interactions : CTDSCAF4
Pharm GKB GenePA134903281
PharosO95104
Clinical trialSCAF4
Miscellaneous
canSAR (ICR)SCAF4
HarmonizomeSCAF4
DataMed IndexSCAF4
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSCAF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 16:19:49 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.