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SCAP (SREBF chaperone)

Identity

Alias_symbol (synonym)KIAA0199
Other alias-
HGNC (Hugo) SCAP
LocusID (NCBI) 22937
Atlas_Id 53340
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 47413685 and ends at 47475959 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AMZ2 (17q24.2) / SCAP (3p21.31)SCAP (3p21.31) / SLC25A20 (3p21.31)SCAP (3p21.31) / SMARCC1 (3p21.31)
SORT1 (1p13.3) / SCAP (3p21.31)SCAP 3p21.31 / SLC25A20 3p21.31SCAP 3p21.31 / SMARCC1 3p21.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SCAP   30634
Cards
Entrez_Gene (NCBI)SCAP  22937  SREBF chaperone
Aliases
GeneCards (Weizmann)SCAP
Ensembl hg19 (Hinxton)ENSG00000114650 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114650 [Gene_View]  chr3:47413685-47475959 [Contig_View]  SCAP [Vega]
ICGC DataPortalENSG00000114650
TCGA cBioPortalSCAP
AceView (NCBI)SCAP
Genatlas (Paris)SCAP
WikiGenes22937
SOURCE (Princeton)SCAP
Genetics Home Reference (NIH)SCAP
Genomic and cartography
GoldenPath hg38 (UCSC)SCAP  -     chr3:47413685-47475959 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCAP  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblSCAP - 3p21.31 [CytoView hg19]  SCAP - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBISCAP [Mapview hg19]  SCAP [Mapview hg38]
OMIM601510   
Gene and transcription
Genbank (Entrez)AK027402 AK074312 AK075528 AK091005 AK291484
RefSeq transcript (Entrez)NM_001320044 NM_012235
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SCAP
Cluster EST : UnigeneHs.531789 [ NCBI ]
CGAP (NCI)Hs.531789
Alternative Splicing GalleryENSG00000114650
Gene ExpressionSCAP [ NCBI-GEO ]   SCAP [ EBI - ARRAY_EXPRESS ]   SCAP [ SEEK ]   SCAP [ MEM ]
Gene Expression Viewer (FireBrowse)SCAP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22937
GTEX Portal (Tissue expression)SCAP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12770   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ12770  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ12770
Splice isoforms : SwissVarQ12770
PhosPhoSitePlusQ12770
Domaine pattern : Prosite (Expaxy)SSD (PS50156)    WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)SCAP    SSD    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)Sterol-sensing (PF12349)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam12349    pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)SCAP
DMDM Disease mutations22937
Blocks (Seattle)SCAP
SuperfamilyQ12770
Human Protein AtlasENSG00000114650
Peptide AtlasQ12770
HPRD03300
IPIIPI00006280   IPI00290700   IPI00290701   IPI00396357   IPI00448910   IPI01015900   IPI00790533   IPI00927367   IPI00925892   IPI00926512   IPI00926330   IPI00926090   
Protein Interaction databases
DIP (DOE-UCLA)Q12770
IntAct (EBI)Q12770
FunCoupENSG00000114650
BioGRIDSCAP
STRING (EMBL)SCAP
ZODIACSCAP
Ontologies - Pathways
QuickGOQ12770
Ontology : AmiGOGolgi membrane  response to hypoxia  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi apparatus  aging  cholesterol metabolic process  ER to Golgi transport vesicle membrane  cholesterol binding  integral component of membrane  protein complex binding  response to insulin  SREBP signaling pathway  regulation of fatty acid biosynthetic process  protein complex  negative regulation of cholesterol biosynthetic process  positive regulation of low-density lipoprotein particle receptor biosynthetic process  unfolded protein binding  
Ontology : EGO-EBIGolgi membrane  response to hypoxia  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi apparatus  aging  cholesterol metabolic process  ER to Golgi transport vesicle membrane  cholesterol binding  integral component of membrane  protein complex binding  response to insulin  SREBP signaling pathway  regulation of fatty acid biosynthetic process  protein complex  negative regulation of cholesterol biosynthetic process  positive regulation of low-density lipoprotein particle receptor biosynthetic process  unfolded protein binding  
Pathways : BIOCARTASREBP control of lipid synthesis [Genes]   
NDEx NetworkSCAP
Atlas of Cancer Signalling NetworkSCAP
Wikipedia pathwaysSCAP
Orthology - Evolution
OrthoDB22937
GeneTree (enSembl)ENSG00000114650
Phylogenetic Trees/Animal Genes : TreeFamSCAP
HOVERGENQ12770
HOGENOMQ12770
Homologs : HomoloGeneSCAP
Homology/Alignments : Family Browser (UCSC)SCAP
Gene fusions - Rearrangements
Fusion : MitelmanSCAP/SLC25A20 [3p21.31/3p21.31]  
Fusion : MitelmanSCAP/SMARCC1 [3p21.31/3p21.31]  [t(3;3)(p21;p21)]  
Fusion: TCGASCAP 3p21.31 SLC25A20 3p21.31 OV
Fusion: TCGASCAP 3p21.31 SMARCC1 3p21.31 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCAP
dbVarSCAP
ClinVarSCAP
1000_GenomesSCAP 
Exome Variant ServerSCAP
ExAC (Exome Aggregation Consortium)SCAP (select the gene name)
Genetic variants : HAPMAP22937
Genomic Variants (DGV)SCAP [DGVbeta]
DECIPHERSCAP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCAP 
Mutations
ICGC Data PortalSCAP 
TCGA Data PortalSCAP 
Broad Tumor PortalSCAP
OASIS PortalSCAP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCAP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSCAP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SCAP
DgiDB (Drug Gene Interaction Database)SCAP
DoCM (Curated mutations)SCAP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SCAP (select a term)
intoGenSCAP
Cancer3DSCAP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601510   
Orphanet
MedgenSCAP
Genetic Testing Registry SCAP
NextProtQ12770 [Medical]
TSGene22937
GENETestsSCAP
Huge Navigator SCAP [HugePedia]
snp3D : Map Gene to Disease22937
BioCentury BCIQSCAP
ClinGenSCAP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22937
Chemical/Pharm GKB GenePA162402461
Clinical trialSCAP
Miscellaneous
canSAR (ICR)SCAP (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSCAP
EVEXSCAP
GoPubMedSCAP
iHOPSCAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:36:11 CEST 2017

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