SCARA3 (scavenger receptor class A member 3)

2007-02-01  

Identity

HGNC
SCARA3
LOCATION
8p21.1
LOCUSID
51435
ALIAS
APC7,CSR,CSR1,MSLR1,MSRL1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51435
MIM: 602728
HGNC: 19000
Ensembl: ENSG00000168077

Variants:

dbSNP: 51435
ClinVar: 51435
TCGA: ENSG00000168077
COSMIC: SCARA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168077ENST00000301904Q6AZY7
ENSG00000168077ENST00000337221Q6AZY7

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
221380342012Scavenger receptor-mediated uptake of cell-penetrating peptide nanocomplexes with oligonucleotides.29
164366732006CSR1 suppresses tumor growth and metastasis of prostate cancer.25
188068232009CSR1 induces cell death through inactivation of CPSF3.15
235377072013Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma.12
204854442010Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population.9
259560322015Oncogenic Activity of miR-650 in Prostate Cancer Is Mediated by Suppression of CSR1 Expression.9
218551132012SCARA3 mRNA is overexpressed in ovarian carcinoma compared with breast carcinoma effusions.8
226833112012Interaction of CSR1 with XIAP reverses inhibition of caspases and accelerates cell death.4
244915632014A cellular stress response (CSR) that interacts with NADPH-P450 reductase (NPR) is a new regulator of hypoxic response.1
289759862017CSR1 suppresses tumor growth and metastasis of human hepatocellular carcinoma via inhibition of HPIP.1

Citation

Dessen P

SCARA3 (scavenger receptor class A member 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45966/scara3