Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SCGB1A1 (secretoglobin family 1A member 1)

Identity

Alias_namesUGB
uteroglobin
Alias_symbol (synonym)CC10
CCSP
CC16
Other aliasCCPBP
UP-1
UP1
HGNC (Hugo) SCGB1A1
LocusID (NCBI) 7356
Atlas_Id 42209
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62419035 and ends at 62423206 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SCGB1A1 (11q12.3) / RAB27A (15q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SCGB1A1   12523
Cards
Entrez_Gene (NCBI)SCGB1A1  7356  secretoglobin family 1A member 1
AliasesCC10; CC16; CCPBP; CCSP; 
UGB; UP-1; UP1
GeneCards (Weizmann)SCGB1A1
Ensembl hg19 (Hinxton)ENSG00000149021 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149021 [Gene_View]  chr11:62419035-62423206 [Contig_View]  SCGB1A1 [Vega]
ICGC DataPortalENSG00000149021
TCGA cBioPortalSCGB1A1
AceView (NCBI)SCGB1A1
Genatlas (Paris)SCGB1A1
WikiGenes7356
SOURCE (Princeton)SCGB1A1
Genetics Home Reference (NIH)SCGB1A1
Genomic and cartography
GoldenPath hg38 (UCSC)SCGB1A1  -     chr11:62419035-62423206 +  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCGB1A1  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblSCGB1A1 - 11q12.3 [CytoView hg19]  SCGB1A1 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBISCGB1A1 [Mapview hg19]  SCGB1A1 [Mapview hg38]
OMIM192020   
Gene and transcription
Genbank (Entrez)AK312165 BC004481 CR541780 DB196705 KU178373
RefSeq transcript (Entrez)NM_003357
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SCGB1A1
Cluster EST : UnigeneHs.523732 [ NCBI ]
CGAP (NCI)Hs.523732
Alternative Splicing GalleryENSG00000149021
Gene ExpressionSCGB1A1 [ NCBI-GEO ]   SCGB1A1 [ EBI - ARRAY_EXPRESS ]   SCGB1A1 [ SEEK ]   SCGB1A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SCGB1A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7356
GTEX Portal (Tissue expression)SCGB1A1
Human Protein AtlasENSG00000149021-SCGB1A1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP11684   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP11684  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP11684
Splice isoforms : SwissVarP11684
PhosPhoSitePlusP11684
Domaine pattern : Prosite (Expaxy)SCGB (PS51311)   
Domains : Interpro (EBI)Secretoglobin    Uteroglobin   
Domain families : Pfam (Sanger)Uteroglobin (PF01099)   
Domain families : Pfam (NCBI)pfam01099   
Domain families : Smart (EMBL)UTG (SM00096)  
Conserved Domain (NCBI)SCGB1A1
DMDM Disease mutations7356
Blocks (Seattle)SCGB1A1
SuperfamilyP11684
Human Protein Atlas [tissue]ENSG00000149021-SCGB1A1 [tissue]
Peptide AtlasP11684
HPRD01884
IPIIPI00006705   IPI00976299   
Protein Interaction databases
DIP (DOE-UCLA)P11684
IntAct (EBI)P11684
FunCoupENSG00000149021
BioGRIDSCGB1A1
STRING (EMBL)SCGB1A1
ZODIACSCGB1A1
Ontologies - Pathways
QuickGOP11684
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  protein binding  extracellular space  nuclear envelope  rough endoplasmic reticulum  signal transduction  female pregnancy  embryo implantation  response to xenobiotic stimulus  response to ozone  phospholipase A2 inhibitor activity  secretory granule  response to lipopolysaccharide  negative regulation of interferon-gamma production  negative regulation of interleukin-13 production  negative regulation of interleukin-4 production  negative regulation of interleukin-5 production  response to silicon dioxide  response to cytokine  negative regulation of T cell proliferation  negative regulation of catalytic activity  regulation of mRNA stability  regulation of inflammatory response  response to glucocorticoid  extracellular exosome  response to fibroblast growth factor  polychlorinated biphenyl binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  protein binding  extracellular space  nuclear envelope  rough endoplasmic reticulum  signal transduction  female pregnancy  embryo implantation  response to xenobiotic stimulus  response to ozone  phospholipase A2 inhibitor activity  secretory granule  response to lipopolysaccharide  negative regulation of interferon-gamma production  negative regulation of interleukin-13 production  negative regulation of interleukin-4 production  negative regulation of interleukin-5 production  response to silicon dioxide  response to cytokine  negative regulation of T cell proliferation  negative regulation of catalytic activity  regulation of mRNA stability  regulation of inflammatory response  response to glucocorticoid  extracellular exosome  response to fibroblast growth factor  polychlorinated biphenyl binding  
NDEx NetworkSCGB1A1
Atlas of Cancer Signalling NetworkSCGB1A1
Wikipedia pathwaysSCGB1A1
Orthology - Evolution
OrthoDB7356
GeneTree (enSembl)ENSG00000149021
Phylogenetic Trees/Animal Genes : TreeFamSCGB1A1
HOVERGENP11684
HOGENOMP11684
Homologs : HomoloGeneSCGB1A1
Homology/Alignments : Family Browser (UCSC)SCGB1A1
Gene fusions - Rearrangements
Fusion : QuiverSCGB1A1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCGB1A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCGB1A1
dbVarSCGB1A1
ClinVarSCGB1A1
1000_GenomesSCGB1A1 
Exome Variant ServerSCGB1A1
ExAC (Exome Aggregation Consortium)ENSG00000149021
GNOMAD BrowserENSG00000149021
Genetic variants : HAPMAP7356
Genomic Variants (DGV)SCGB1A1 [DGVbeta]
DECIPHERSCGB1A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCGB1A1 
Mutations
ICGC Data PortalSCGB1A1 
TCGA Data PortalSCGB1A1 
Broad Tumor PortalSCGB1A1
OASIS PortalSCGB1A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCGB1A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSCGB1A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SCGB1A1
DgiDB (Drug Gene Interaction Database)SCGB1A1
DoCM (Curated mutations)SCGB1A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SCGB1A1 (select a term)
intoGenSCGB1A1
Cancer3DSCGB1A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM192020   
Orphanet
DisGeNETSCGB1A1
MedgenSCGB1A1
Genetic Testing Registry SCGB1A1
NextProtP11684 [Medical]
TSGene7356
GENETestsSCGB1A1
Target ValidationSCGB1A1
Huge Navigator SCGB1A1 [HugePedia]
snp3D : Map Gene to Disease7356
BioCentury BCIQSCGB1A1
ClinGenSCGB1A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7356
Chemical/Pharm GKB GenePA34989
Clinical trialSCGB1A1
Miscellaneous
canSAR (ICR)SCGB1A1 (select the gene name)
Probes
Litterature
PubMed150 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSCGB1A1
EVEXSCGB1A1
GoPubMedSCGB1A1
iHOPSCGB1A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Feb 28 13:36:16 CET 2018
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