SCGB3A1 (secretoglobin family 3A member 1)

2003-02-01  

Identity

HGNC
LOCATION
5q35.3
LOCUSID
ALIAS
HIN-1,HIN1,LU105,PnSP-2,UGRP2
FUSION GENES

Other Information

Locus ID:

NCBI: 92304
MIM: 606500
HGNC: 18384
Ensembl: ENSG00000161055

Variants:

dbSNP: 92304
ClinVar: 92304
TCGA: ENSG00000161055
COSMIC: SCGB3A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161055ENST00000292641Q96QR1

Expression (GTEx)

0
100
200
300
400
500
600

References

Pubmed IDYearTitleCitations
146010572003DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma.77
176230562007DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets.48
175455222007Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome.36
184833252008DNA methylation in benign breast epithelium in relation to age and breast cancer risk.34
162669852005HIN-1, an inhibitor of cell growth, invasion, and AKT activation.27
195091632009Methylation of RASSF1A, RASSF2A, and HIN-1 is associated with poor outcome after radiotherapy, but not surgery, in oral squamous cell carcinoma.27
154729082005Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies.26
226954912012Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome.23
153836272004Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types.20
190984482008Promoter methylation of HIN-1 in the progression to esophageal squamous cancer.20

Citation

Dessen P

SCGB3A1 (secretoglobin family 3A member 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/42214/scgb3a1