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SCML4 (Scm polycomb group protein like 4)

Identity

Alias_symbol (synonym)dJ47M23.1
Other alias
HGNC (Hugo) SCML4
LocusID (NCBI) 256380
Atlas_Id 54604
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 107702157 and ends at 107824317 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEP85L (6q22.31) / SCML4 (6q21)MRPS22 (3q23) / SCML4 (6q21)SCML4 (6q21) / TUSC3 (8p22)
ZBTB24 (6q21) / SCML4 (6q21)SCML4 6q21 / TUSC3 8p22ZBTB24 6q21 / SCML4 6q21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Small Cell Carcinoma
del(6)(q21q22) CEP85L/SCML4


External links

Nomenclature
HGNC (Hugo)SCML4   21397
Cards
Entrez_Gene (NCBI)SCML4  256380  Scm polycomb group protein like 4
AliasesdJ47M23.1
GeneCards (Weizmann)SCML4
Ensembl hg19 (Hinxton)ENSG00000146285 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146285 [Gene_View]  ENSG00000146285 [Sequence]  chr6:107702157-107824317 [Contig_View]  SCML4 [Vega]
ICGC DataPortalENSG00000146285
TCGA cBioPortalSCML4
AceView (NCBI)SCML4
Genatlas (Paris)SCML4
WikiGenes256380
SOURCE (Princeton)SCML4
Genetics Home Reference (NIH)SCML4
Genomic and cartography
GoldenPath hg38 (UCSC)SCML4  -     chr6:107702157-107824317 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCML4  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblSCML4 - 6q21 [CytoView hg19]  SCML4 - 6q21 [CytoView hg38]
Mapping of homologs : NCBISCML4 [Mapview hg19]  SCML4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB072902 AK074125 AK092812 AK093571 AK128420
RefSeq transcript (Entrez)NM_001286408 NM_001286409 NM_198081
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SCML4
Cluster EST : UnigeneHs.587364 [ NCBI ]
CGAP (NCI)Hs.587364
Alternative Splicing GalleryENSG00000146285
Gene ExpressionSCML4 [ NCBI-GEO ]   SCML4 [ EBI - ARRAY_EXPRESS ]   SCML4 [ SEEK ]   SCML4 [ MEM ]
Gene Expression Viewer (FireBrowse)SCML4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)256380
GTEX Portal (Tissue expression)SCML4
Human Protein AtlasENSG00000146285-SCML4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N228   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N228  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N228
Splice isoforms : SwissVarQ8N228
PhosPhoSitePlusQ8N228
Domains : Interpro (EBI)SAM    SAM/pointed_sf    SCML2_RBR    SLED    SLED_sf   
Domain families : Pfam (Sanger)RBR (PF17208)    SAM_1 (PF00536)    SLED (PF12140)   
Domain families : Pfam (NCBI)pfam17208    pfam00536    pfam12140   
Domain families : Smart (EMBL)SAM (SM00454)  
Conserved Domain (NCBI)SCML4
DMDM Disease mutations256380
Blocks (Seattle)SCML4
SuperfamilyQ8N228
Human Protein Atlas [tissue]ENSG00000146285-SCML4 [tissue]
Peptide AtlasQ8N228
HPRD10212
IPIIPI00646082   IPI00877639   IPI00640008   IPI00791529   IPI00641558   
Protein Interaction databases
DIP (DOE-UCLA)Q8N228
IntAct (EBI)Q8N228
FunCoupENSG00000146285
BioGRIDSCML4
STRING (EMBL)SCML4
ZODIACSCML4
Ontologies - Pathways
QuickGOQ8N228
Ontology : AmiGOnucleoplasm  
Ontology : EGO-EBInucleoplasm  
NDEx NetworkSCML4
Atlas of Cancer Signalling NetworkSCML4
Wikipedia pathwaysSCML4
Orthology - Evolution
OrthoDB256380
GeneTree (enSembl)ENSG00000146285
Phylogenetic Trees/Animal Genes : TreeFamSCML4
HOVERGENQ8N228
HOGENOMQ8N228
Homologs : HomoloGeneSCML4
Homology/Alignments : Family Browser (UCSC)SCML4
Gene fusions - Rearrangements
Fusion : MitelmanCEP85L/SCML4 [6q22.31/6q21]  [del(6)(q21q22)]  
Fusion PortalSCML4 6q21 TUSC3 8p22 BRCA
Fusion PortalZBTB24 6q21 SCML4 6q21 BRCA
Fusion : QuiverSCML4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCML4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCML4
dbVarSCML4
ClinVarSCML4
1000_GenomesSCML4 
Exome Variant ServerSCML4
ExAC (Exome Aggregation Consortium)ENSG00000146285
GNOMAD BrowserENSG00000146285
Varsome BrowserSCML4
Genetic variants : HAPMAP256380
Genomic Variants (DGV)SCML4 [DGVbeta]
DECIPHERSCML4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCML4 
Mutations
ICGC Data PortalSCML4 
TCGA Data PortalSCML4 
Broad Tumor PortalSCML4
OASIS PortalSCML4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCML4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSCML4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SCML4
DgiDB (Drug Gene Interaction Database)SCML4
DoCM (Curated mutations)SCML4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SCML4 (select a term)
intoGenSCML4
Cancer3DSCML4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSCML4
MedgenSCML4
Genetic Testing Registry SCML4
NextProtQ8N228 [Medical]
TSGene256380
GENETestsSCML4
Target ValidationSCML4
Huge Navigator SCML4 [HugePedia]
snp3D : Map Gene to Disease256380
BioCentury BCIQSCML4
ClinGenSCML4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD256380
Chemical/Pharm GKB GenePA134946179
Clinical trialSCML4
Miscellaneous
canSAR (ICR)SCML4 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSCML4
EVEXSCML4
GoPubMedSCML4
iHOPSCML4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:37:36 CET 2018

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