Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6339
MIM: 601328
HGNC: 10601
Ensembl: ENSG00000162572
Variants:
dbSNP: 6339
ClinVar: 6339
TCGA: ENSG00000162572
COSMIC: SCNN1D
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Transmembrane transport of small molecules | REACTOME | R-HSA-382551 |
| Ion channel transport | REACTOME | R-HSA-983712 |
| Stimuli-sensing channels | REACTOME | R-HSA-2672351 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36193739 | 2022 | Rare Variants in Genes Encoding Subunits of the Epithelial Na(+) Channel Are Associated With Blood Pressure and Kidney Function. | 10 |
| 36193739 | 2022 | Rare Variants in Genes Encoding Subunits of the Epithelial Na(+) Channel Are Associated With Blood Pressure and Kidney Function. | 10 |
| 33673381 | 2021 | CRISPR/Cas9 Mediated Knock Down of δ-ENaC Blunted the TNF-Induced Activation of ENaC in A549 Cells. | 6 |
| 33673381 | 2021 | CRISPR/Cas9 Mediated Knock Down of δ-ENaC Blunted the TNF-Induced Activation of ENaC in A549 Cells. | 6 |
| 31754387 | 2019 | Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene. | 10 |
| 31754387 | 2019 | Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene. | 10 |
| 27941075 | 2017 | δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes. | 6 |
| 28708422 | 2017 | The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations. | 18 |
| 27941075 | 2017 | δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes. | 6 |
| 28708422 | 2017 | The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations. | 18 |
| 25677639 | 2015 | Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro. | 3 |
| 25677639 | 2015 | Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro. | 3 |
| 22159085 | 2012 | Differential N termini in epithelial Na+ channel δ-subunit isoforms modulate channel trafficking to the membrane. | 11 |
| 22505667 | 2012 | Characterization of a novel splice variant of δ ENaC subunit in human lungs. | 12 |
| 22159085 | 2012 | Differential N termini in epithelial Na+ channel δ-subunit isoforms modulate channel trafficking to the membrane. | 11 |
Citation
Dessen P
SCNN1D (sodium channel epithelial 1 subunit delta)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/42216/scnn1d
