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SCP2 (sterol carrier protein 2)

Identity

Other aliasNLTP
NSL-TP
SCP-2
SCP-CHI
SCP-X
SCPX
HGNC (Hugo) SCP2
LocusID (NCBI) 6342
Atlas_Id 73054
Location 1p32.3  [Link to chromosome band 1p32]
Location_base_pair Starts at 52927229 and ends at 52994232 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CPT2 (1p32.3) / SCP2 (1p32.3)NFIA (1p31.3) / SCP2 (1p32.3)SCP2 (1p32.3) / ECHDC2 (1p32.3)
SCP2 (1p32.3) / PJA2 (5q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SCP2   10606
Cards
Entrez_Gene (NCBI)SCP2  6342  sterol carrier protein 2
AliasesNLTP; NSL-TP; SCP-2; SCP-CHI; 
SCP-X; SCPX
GeneCards (Weizmann)SCP2
Ensembl hg19 (Hinxton)ENSG00000116171 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116171 [Gene_View]  chr1:52927229-52994232 [Contig_View]  SCP2 [Vega]
ICGC DataPortalENSG00000116171
TCGA cBioPortalSCP2
AceView (NCBI)SCP2
Genatlas (Paris)SCP2
WikiGenes6342
SOURCE (Princeton)SCP2
Genetics Home Reference (NIH)SCP2
Genomic and cartography
GoldenPath hg38 (UCSC)SCP2  -     chr1:52927229-52994232 +  1p32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCP2  -     1p32.3   [Description]    (hg19-Feb_2009)
EnsemblSCP2 - 1p32.3 [CytoView hg19]  SCP2 - 1p32.3 [CytoView hg38]
Mapping of homologs : NCBISCP2 [Mapview hg19]  SCP2 [Mapview hg38]
OMIM184755   613724   
Gene and transcription
Genbank (Entrez)AA664009 AB208789 AK294631 AK295214 AK303400
RefSeq transcript (Entrez)NM_001007098 NM_001007099 NM_001007100 NM_001007250 NM_001193599 NM_001193600 NM_001193617 NM_001330587 NM_002979
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SCP2
Cluster EST : UnigeneHs.476365 [ NCBI ]
CGAP (NCI)Hs.476365
Alternative Splicing GalleryENSG00000116171
Gene ExpressionSCP2 [ NCBI-GEO ]   SCP2 [ EBI - ARRAY_EXPRESS ]   SCP2 [ SEEK ]   SCP2 [ MEM ]
Gene Expression Viewer (FireBrowse)SCP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6342
GTEX Portal (Tissue expression)SCP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP22307   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP22307  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP22307
Splice isoforms : SwissVarP22307
Catalytic activity : Enzyme2.3.1.176 [ Enzyme-Expasy ]   2.3.1.1762.3.1.176 [ IntEnz-EBI ]   2.3.1.176 [ BRENDA ]   2.3.1.176 [ KEGG ]   
PhosPhoSitePlusP22307
Domaine pattern : Prosite (Expaxy)THIOLASE_1 (PS00098)    THIOLASE_2 (PS00737)   
Domains : Interpro (EBI)SCP2_sterol-bd_dom    Thiolase-like    Thiolase_acyl_enz_int_AS    Thiolase_C    Thiolase_CS    Thiolase_N   
Domain families : Pfam (Sanger)SCP2 (PF02036)    Thiolase_C (PF02803)    Thiolase_N (PF00108)   
Domain families : Pfam (NCBI)pfam02036    pfam02803    pfam00108   
Conserved Domain (NCBI)SCP2
DMDM Disease mutations6342
Blocks (Seattle)SCP2
PDB (SRS)1QND    2C0L   
PDB (PDBSum)1QND    2C0L   
PDB (IMB)1QND    2C0L   
PDB (RSDB)1QND    2C0L   
Structural Biology KnowledgeBase1QND    2C0L   
SCOP (Structural Classification of Proteins)1QND    2C0L   
CATH (Classification of proteins structures)1QND    2C0L   
SuperfamilyP22307
Human Protein AtlasENSG00000116171
Peptide AtlasP22307
HPRD01700
IPIIPI00026105   IPI00943320   IPI00909685   IPI01009036   IPI00556015   IPI00977865   IPI00973807   IPI00479510   IPI00433347   IPI00979523   IPI00479934   IPI00977166   IPI00979623   IPI00479311   
Protein Interaction databases
DIP (DOE-UCLA)P22307
IntAct (EBI)P22307
FunCoupENSG00000116171
BioGRIDSCP2
STRING (EMBL)SCP2
ZODIACSCP2
Ontologies - Pathways
QuickGOP22307
Ontology : AmiGOfatty-acyl-CoA binding  receptor binding  protein binding  nucleoplasm  mitochondrion  peroxisome  peroxisomal matrix  steroid biosynthetic process  bile acid biosynthetic process  peroxisome organization  sterol transporter activity  cholesterol binding  phospholipid transport  sterol transport  membrane  positive regulation of intracellular cholesterol transport  fatty acid beta-oxidation using acyl-CoA oxidase  propanoyl-CoA C-acyltransferase activity  long-chain fatty acyl-CoA binding  alpha-linolenic acid metabolic process  intracellular membrane-bounded organelle  protein complex  propionyl-CoA C2-trimethyltridecanoyltransferase activity  propionyl-CoA C2-trimethyltridecanoyltransferase activity  extracellular exosome  oleic acid binding  lipid hydroperoxide transport  
Ontology : EGO-EBIfatty-acyl-CoA binding  receptor binding  protein binding  nucleoplasm  mitochondrion  peroxisome  peroxisomal matrix  steroid biosynthetic process  bile acid biosynthetic process  peroxisome organization  sterol transporter activity  cholesterol binding  phospholipid transport  sterol transport  membrane  positive regulation of intracellular cholesterol transport  fatty acid beta-oxidation using acyl-CoA oxidase  propanoyl-CoA C-acyltransferase activity  long-chain fatty acyl-CoA binding  alpha-linolenic acid metabolic process  intracellular membrane-bounded organelle  protein complex  propionyl-CoA C2-trimethyltridecanoyltransferase activity  propionyl-CoA C2-trimethyltridecanoyltransferase activity  extracellular exosome  oleic acid binding  lipid hydroperoxide transport  
Pathways : KEGGPrimary bile acid biosynthesis    PPAR signaling pathway    Peroxisome   
NDEx NetworkSCP2
Atlas of Cancer Signalling NetworkSCP2
Wikipedia pathwaysSCP2
Orthology - Evolution
OrthoDB6342
GeneTree (enSembl)ENSG00000116171
Phylogenetic Trees/Animal Genes : TreeFamSCP2
HOVERGENP22307
HOGENOMP22307
Homologs : HomoloGeneSCP2
Homology/Alignments : Family Browser (UCSC)SCP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCP2
dbVarSCP2
ClinVarSCP2
1000_GenomesSCP2 
Exome Variant ServerSCP2
ExAC (Exome Aggregation Consortium)SCP2 (select the gene name)
Genetic variants : HAPMAP6342
Genomic Variants (DGV)SCP2 [DGVbeta]
DECIPHERSCP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCP2 
Mutations
ICGC Data PortalSCP2 
TCGA Data PortalSCP2 
Broad Tumor PortalSCP2
OASIS PortalSCP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSCP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SCP2
DgiDB (Drug Gene Interaction Database)SCP2
DoCM (Curated mutations)SCP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SCP2 (select a term)
intoGenSCP2
Cancer3DSCP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM184755    613724   
Orphanet17522   
MedgenSCP2
Genetic Testing Registry SCP2
NextProtP22307 [Medical]
TSGene6342
GENETestsSCP2
Target ValidationSCP2
Huge Navigator SCP2 [HugePedia]
snp3D : Map Gene to Disease6342
BioCentury BCIQSCP2
ClinGenSCP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6342
Chemical/Pharm GKB GenePA35014
Clinical trialSCP2
Miscellaneous
canSAR (ICR)SCP2 (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSCP2
EVEXSCP2
GoPubMedSCP2
iHOPSCP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:37:22 CEST 2017

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