SCUBE1 (signal peptide, CUB domain and EGF like domain containing 1)

2013-05-01  

Identity

HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 80274
MIM: 611746
HGNC: 13441
Ensembl: ENSG00000159307

Variants:

dbSNP: 80274
ClinVar: 80274
TCGA: ENSG00000159307
COSMIC: SCUBE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159307ENST00000290460B1AH90
ENSG00000159307ENST00000360835Q8IWY4
ENSG00000159307ENST00000449304H0Y4Y9
ENSG00000159307ENST00000615096A0A087X285

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
122709312002Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.35
209628502011A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles.21
231363972013Reduction of pro-tumorigenic activity of human prostate cancer-associated fibroblasts using Dlk1 or SCUBE1.9
232208512012Is SCUBE 1 a new biomarker for gastric cancer?4
236323012013The diagnostic and prognostic significance of SCUBE1 levels in Crimean-Congo hemorrhagic fever.3
264382142015Elevated Serum Levels of SCUBE1, a Marker for Coagulation, in Patients with Breast Cancer.3
228744832012Signal peptide-CUB-EGF domain-containing protein 1 (SCUBE1) level in hemodialysis patients and parameters affecting that level.2
266999032016Electrostatics and N-glycan-mediated membrane tethering of SCUBE1 is critical for promoting bone morphogenetic protein signalling.2
272655252016Increased serum concentrations of signal peptide-Cub-Egf domain-containing protein-1 in patients with aneurysmal subarachnoid hemorrhage.1
274960802016The prognostic value of serum signal peptide-Cub-Egf domain-containing protein-1 concentrations in acute intracerebral hemorrhage.1

Citation

Dessen P

SCUBE1 (signal peptide, CUB domain and EGF like domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53325/scube1