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SCUBE2 (signal peptide, CUB domain and EGF like domain containing 2)

Identity

Alias_namessignal peptide
Alias_symbol (synonym)Cegf1
Cegb1
FLJ16792
Other aliasCEGB1
CEGF1
CEGP1
HGNC (Hugo) SCUBE2
LocusID (NCBI) 57758
Atlas_Id 50982
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 9019500 and ends at 9091603 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SCUBE2 (11p15.4) / SCUBE2 (11p15.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SCUBE2   30425
Cards
Entrez_Gene (NCBI)SCUBE2  57758  signal peptide, CUB domain and EGF like domain containing 2
AliasesCEGB1; CEGF1; CEGP1
GeneCards (Weizmann)SCUBE2
Ensembl hg19 (Hinxton)ENSG00000175356 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175356 [Gene_View]  chr11:9019500-9091603 [Contig_View]  SCUBE2 [Vega]
ICGC DataPortalENSG00000175356
TCGA cBioPortalSCUBE2
AceView (NCBI)SCUBE2
Genatlas (Paris)SCUBE2
WikiGenes57758
SOURCE (Princeton)SCUBE2
Genetics Home Reference (NIH)SCUBE2
Genomic and cartography
GoldenPath hg38 (UCSC)SCUBE2  -     chr11:9019500-9091603 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCUBE2  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblSCUBE2 - 11p15.4 [CytoView hg19]  SCUBE2 - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBISCUBE2 [Mapview hg19]  SCUBE2 [Mapview hg38]
OMIM611747   
Gene and transcription
Genbank (Entrez)AF086390 AK092153 AK092553 AK123039 AK131552
RefSeq transcript (Entrez)NM_001170690 NM_001330199 NM_020974
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SCUBE2
Cluster EST : UnigeneHs.523468 [ NCBI ]
CGAP (NCI)Hs.523468
Alternative Splicing GalleryENSG00000175356
Gene ExpressionSCUBE2 [ NCBI-GEO ]   SCUBE2 [ EBI - ARRAY_EXPRESS ]   SCUBE2 [ SEEK ]   SCUBE2 [ MEM ]
Gene Expression Viewer (FireBrowse)SCUBE2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57758
GTEX Portal (Tissue expression)SCUBE2
Human Protein AtlasENSG00000175356-SCUBE2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQ36   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQ36  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQ36
Splice isoforms : SwissVarQ9NQ36
PhosPhoSitePlusQ9NQ36
Domaine pattern : Prosite (Expaxy)ASX_HYDROXYL (PS00010)    CUB (PS01180)    EGF_2 (PS01186)    EGF_3 (PS50026)    EGF_CA (PS01187)   
Domains : Interpro (EBI)cEGF    CUB_dom    EGF-like_Ca-bd_dom    EGF-like_CS    EGF-like_dom    EGF-type_Asp/Asn_hydroxyl_site    EGF_Ca-bd_CS    EGF_dom    Growth_fac_rcpt_    Tyr-kin_ephrin_A/B_rcpt-like   
Domain families : Pfam (Sanger)cEGF (PF12662)    CUB (PF00431)    EGF_3 (PF12947)    EGF_CA (PF07645)    Ephrin_rec_like (PF07699)   
Domain families : Pfam (NCBI)pfam12662    pfam00431    pfam12947    pfam07645    pfam07699   
Domain families : Smart (EMBL)CUB (SM00042)  EGF (SM00181)  EGF_CA (SM00179)  Ephrin_rec_like (SM01411)  
Conserved Domain (NCBI)SCUBE2
DMDM Disease mutations57758
Blocks (Seattle)SCUBE2
SuperfamilyQ9NQ36
Human Protein Atlas [tissue]ENSG00000175356-SCUBE2 [tissue]
Peptide AtlasQ9NQ36
HPRD18030
IPIIPI00024880   IPI00789188   IPI00442002   IPI00983351   IPI00976018   IPI00976563   IPI00976675   IPI00975983   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQ36
IntAct (EBI)Q9NQ36
FunCoupENSG00000175356
BioGRIDSCUBE2
STRING (EMBL)SCUBE2
ZODIACSCUBE2
Ontologies - Pathways
QuickGOQ9NQ36
Ontology : AmiGOcalcium ion binding  extracellular region  extracellular space  signal transduction  cell surface  cell differentiation  
Ontology : EGO-EBIcalcium ion binding  extracellular region  extracellular space  signal transduction  cell surface  cell differentiation  
NDEx NetworkSCUBE2
Atlas of Cancer Signalling NetworkSCUBE2
Wikipedia pathwaysSCUBE2
Orthology - Evolution
OrthoDB57758
GeneTree (enSembl)ENSG00000175356
Phylogenetic Trees/Animal Genes : TreeFamSCUBE2
HOVERGENQ9NQ36
HOGENOMQ9NQ36
Homologs : HomoloGeneSCUBE2
Homology/Alignments : Family Browser (UCSC)SCUBE2
Gene fusions - Rearrangements
Tumor Fusion PortalSCUBE2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCUBE2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCUBE2
dbVarSCUBE2
ClinVarSCUBE2
1000_GenomesSCUBE2 
Exome Variant ServerSCUBE2
ExAC (Exome Aggregation Consortium)ENSG00000175356
GNOMAD BrowserENSG00000175356
Genetic variants : HAPMAP57758
Genomic Variants (DGV)SCUBE2 [DGVbeta]
DECIPHERSCUBE2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCUBE2 
Mutations
ICGC Data PortalSCUBE2 
TCGA Data PortalSCUBE2 
Broad Tumor PortalSCUBE2
OASIS PortalSCUBE2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCUBE2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSCUBE2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SCUBE2
DgiDB (Drug Gene Interaction Database)SCUBE2
DoCM (Curated mutations)SCUBE2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SCUBE2 (select a term)
intoGenSCUBE2
Cancer3DSCUBE2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611747   
Orphanet
DisGeNETSCUBE2
MedgenSCUBE2
Genetic Testing Registry SCUBE2
NextProtQ9NQ36 [Medical]
TSGene57758
GENETestsSCUBE2
Target ValidationSCUBE2
Huge Navigator SCUBE2 [HugePedia]
snp3D : Map Gene to Disease57758
BioCentury BCIQSCUBE2
ClinGenSCUBE2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57758
Chemical/Pharm GKB GenePA134908812
Clinical trialSCUBE2
Miscellaneous
canSAR (ICR)SCUBE2 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSCUBE2
EVEXSCUBE2
GoPubMedSCUBE2
iHOPSCUBE2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:33:45 CET 2017

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