Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SCYL1 (SCY1 like pseudokinase 1)

Identity

Alias_namesNTKL
N-terminal kinase-like
SCY1-like 1 (S. cerevisiae)
SCY1-like, kinase-like 1
Alias_symbol (synonym)HT019
P105
GKLP
NKTL
TAPK
TRAP
TEIF
MGC78454
Other aliasSCAR21
HGNC (Hugo) SCYL1
LocusID (NCBI) 57410
Atlas_Id 43486
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 65525077 and ends at 65538711 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC30 (1p34.2) / SCYL1 (11q13.1)SCYL1 (11q13.1) / COL1A1 (17q21.33)SCYL1 (11q13.1) / FRMD8 (11q13.1)
SCYL1 (11q13.1) / RPS18 (6p21.32)SCYL1 (11q13.1) / TRPM8 (2q37.1)SCYL1 11q13.1 / FRMD8 11q13.1
SCYL1 11q13.1 / TRPM8 2q37.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SCYL1   14372
Cards
Entrez_Gene (NCBI)SCYL1  57410  SCY1 like pseudokinase 1
AliasesGKLP; HT019; NKTL; NTKL; 
P105; SCAR21; TAPK; TEIF; TRAP
GeneCards (Weizmann)SCYL1
Ensembl hg19 (Hinxton)ENSG00000142186 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142186 [Gene_View]  chr11:65525077-65538711 [Contig_View]  SCYL1 [Vega]
ICGC DataPortalENSG00000142186
TCGA cBioPortalSCYL1
AceView (NCBI)SCYL1
Genatlas (Paris)SCYL1
WikiGenes57410
SOURCE (Princeton)SCYL1
Genetics Home Reference (NIH)SCYL1
Genomic and cartography
GoldenPath hg38 (UCSC)SCYL1  -     chr11:65525077-65538711 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SCYL1  -     11q13.1   [Description]    (hg19-Feb_2009)
EnsemblSCYL1 - 11q13.1 [CytoView hg19]  SCYL1 - 11q13.1 [CytoView hg38]
Mapping of homologs : NCBISCYL1 [Mapview hg19]  SCYL1 [Mapview hg38]
OMIM607982   616719   
Gene and transcription
Genbank (Entrez)AB047077 AB051427 AB051428 AF225424 AF297709
RefSeq transcript (Entrez)NM_001048218 NM_020680
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SCYL1
Cluster EST : UnigeneHs.238839 [ NCBI ]
CGAP (NCI)Hs.238839
Alternative Splicing GalleryENSG00000142186
Gene ExpressionSCYL1 [ NCBI-GEO ]   SCYL1 [ EBI - ARRAY_EXPRESS ]   SCYL1 [ SEEK ]   SCYL1 [ MEM ]
Gene Expression Viewer (FireBrowse)SCYL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57410
GTEX Portal (Tissue expression)SCYL1
Human Protein AtlasENSG00000142186-SCYL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96KG9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96KG9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96KG9
Splice isoforms : SwissVarQ96KG9
PhosPhoSitePlusQ96KG9
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    Kinase-like_dom    Prot_kinase_dom   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Conserved Domain (NCBI)SCYL1
DMDM Disease mutations57410
Blocks (Seattle)SCYL1
SuperfamilyQ96KG9
Human Protein Atlas [tissue]ENSG00000142186-SCYL1 [tissue]
Peptide AtlasQ96KG9
HPRD06414
IPIIPI00102059   IPI00787009   IPI00788043   IPI00062264   IPI00788089   IPI00186969   IPI00908720   IPI00979583   IPI00978883   IPI00979496   IPI00978179   
Protein Interaction databases
DIP (DOE-UCLA)Q96KG9
IntAct (EBI)Q96KG9
FunCoupENSG00000142186
BioGRIDSCYL1
STRING (EMBL)SCYL1
ZODIACSCYL1
Ontologies - Pathways
QuickGOQ96KG9
Ontology : AmiGODNA binding  protein tyrosine kinase activity  ATP binding  nucleus  cytoplasm  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  cis-Golgi network  microtubule organizing center  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  retrograde vesicle-mediated transport, Golgi to ER  membrane  peptidyl-tyrosine phosphorylation  COPI vesicle coat  cadherin binding  
Ontology : EGO-EBIDNA binding  protein tyrosine kinase activity  ATP binding  nucleus  cytoplasm  endoplasmic reticulum-Golgi intermediate compartment  Golgi apparatus  cis-Golgi network  microtubule organizing center  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  retrograde vesicle-mediated transport, Golgi to ER  membrane  peptidyl-tyrosine phosphorylation  COPI vesicle coat  cadherin binding  
NDEx NetworkSCYL1
Atlas of Cancer Signalling NetworkSCYL1
Wikipedia pathwaysSCYL1
Orthology - Evolution
OrthoDB57410
GeneTree (enSembl)ENSG00000142186
Phylogenetic Trees/Animal Genes : TreeFamSCYL1
HOVERGENQ96KG9
HOGENOMQ96KG9
Homologs : HomoloGeneSCYL1
Homology/Alignments : Family Browser (UCSC)SCYL1
Gene fusions - Rearrangements
Fusion : MitelmanSCYL1/FRMD8 [11q13.1/11q13.1]  
Fusion : MitelmanSCYL1/TRPM8 [11q13.1/2q37.1]  [t(2;11)(q37;q13)]  
Fusion: TCGA_MDACCSCYL1 11q13.1 FRMD8 11q13.1 BRCA
Fusion: TCGA_MDACCSCYL1 11q13.1 TRPM8 2q37.1 PRAD
Tumor Fusion PortalSCYL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSCYL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SCYL1
dbVarSCYL1
ClinVarSCYL1
1000_GenomesSCYL1 
Exome Variant ServerSCYL1
ExAC (Exome Aggregation Consortium)ENSG00000142186
GNOMAD BrowserENSG00000142186
Genetic variants : HAPMAP57410
Genomic Variants (DGV)SCYL1 [DGVbeta]
DECIPHERSCYL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSCYL1 
Mutations
ICGC Data PortalSCYL1 
TCGA Data PortalSCYL1 
Broad Tumor PortalSCYL1
OASIS PortalSCYL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSCYL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSCYL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SCYL1
DgiDB (Drug Gene Interaction Database)SCYL1
DoCM (Curated mutations)SCYL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SCYL1 (select a term)
intoGenSCYL1
Cancer3DSCYL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607982    616719   
Orphanet
DisGeNETSCYL1
MedgenSCYL1
Genetic Testing Registry SCYL1
NextProtQ96KG9 [Medical]
TSGene57410
GENETestsSCYL1
Target ValidationSCYL1
Huge Navigator SCYL1 [HugePedia]
snp3D : Map Gene to Disease57410
BioCentury BCIQSCYL1
ClinGenSCYL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57410
Chemical/Pharm GKB GenePA31812
Clinical trialSCYL1
Miscellaneous
canSAR (ICR)SCYL1 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSCYL1
EVEXSCYL1
GoPubMedSCYL1
iHOPSCYL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:33:46 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.