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SDCBP2 (syndecan binding protein 2)

Identity

Alias_namessyndecan binding protein (syntenin) 2
Alias_symbol (synonym)ST-2
SITAC18
Other aliasSITAC
ST2
HGNC (Hugo) SDCBP2
LocusID (NCBI) 27111
Atlas_Id 73064
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 1309911 and ends at 1325869 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FKBP1A (20p13) / SDCBP2 (20p13)S100A4 (1q21.3) / SDCBP2 (20p13)SDCBP2 (20p13) / ADAR (1q21.3)
SDCBP2 (20p13) / SDCBP2 (20p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SDCBP2   15756
Cards
Entrez_Gene (NCBI)SDCBP2  27111  syndecan binding protein 2
AliasesSITAC; SITAC18; ST-2; ST2
GeneCards (Weizmann)SDCBP2
Ensembl hg19 (Hinxton)ENSG00000125775 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125775 [Gene_View]  chr20:1309911-1325869 [Contig_View]  SDCBP2 [Vega]
ICGC DataPortalENSG00000125775
TCGA cBioPortalSDCBP2
AceView (NCBI)SDCBP2
Genatlas (Paris)SDCBP2
WikiGenes27111
SOURCE (Princeton)SDCBP2
Genetics Home Reference (NIH)SDCBP2
Genomic and cartography
GoldenPath hg38 (UCSC)SDCBP2  -     chr20:1309911-1325869 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SDCBP2  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblSDCBP2 - 20p13 [CytoView hg19]  SDCBP2 - 20p13 [CytoView hg38]
Mapping of homologs : NCBISDCBP2 [Mapview hg19]  SDCBP2 [Mapview hg38]
OMIM617358   
Gene and transcription
Genbank (Entrez)AA514519 AA907131 AF131809 AF159228 AJ292244
RefSeq transcript (Entrez)NM_001199784 NM_015685 NM_080489
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SDCBP2
Cluster EST : UnigeneHs.657015 [ NCBI ]
CGAP (NCI)Hs.657015
Alternative Splicing GalleryENSG00000125775
Gene ExpressionSDCBP2 [ NCBI-GEO ]   SDCBP2 [ EBI - ARRAY_EXPRESS ]   SDCBP2 [ SEEK ]   SDCBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)SDCBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27111
GTEX Portal (Tissue expression)SDCBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H190   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H190  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H190
Splice isoforms : SwissVarQ9H190
PhosPhoSitePlusQ9H190
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)   
Domains : Interpro (EBI)PDZ   
Domain families : Pfam (Sanger)PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00595   
Domain families : Smart (EMBL)PDZ (SM00228)  
Conserved Domain (NCBI)SDCBP2
DMDM Disease mutations27111
Blocks (Seattle)SDCBP2
SuperfamilyQ9H190
Human Protein AtlasENSG00000125775
Peptide AtlasQ9H190
HPRD18032
IPIIPI00302318   IPI00220218   IPI00908959   
Protein Interaction databases
DIP (DOE-UCLA)Q9H190
IntAct (EBI)Q9H190
FunCoupENSG00000125775
BioGRIDSDCBP2
STRING (EMBL)SDCBP2
ZODIACSDCBP2
Ontologies - Pathways
QuickGOQ9H190
Ontology : AmiGOprotein binding  cytoplasm  plasma membrane  nervous system development  protein C-terminus binding  intracellular signal transduction  identical protein binding  protein homodimerization activity  intracellular transport  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBIprotein binding  cytoplasm  plasma membrane  nervous system development  protein C-terminus binding  intracellular signal transduction  identical protein binding  protein homodimerization activity  intracellular transport  protein heterodimerization activity  extracellular exosome  
NDEx NetworkSDCBP2
Atlas of Cancer Signalling NetworkSDCBP2
Wikipedia pathwaysSDCBP2
Orthology - Evolution
OrthoDB27111
GeneTree (enSembl)ENSG00000125775
Phylogenetic Trees/Animal Genes : TreeFamSDCBP2
HOVERGENQ9H190
HOGENOMQ9H190
Homologs : HomoloGeneSDCBP2
Homology/Alignments : Family Browser (UCSC)SDCBP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSDCBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SDCBP2
dbVarSDCBP2
ClinVarSDCBP2
1000_GenomesSDCBP2 
Exome Variant ServerSDCBP2
ExAC (Exome Aggregation Consortium)SDCBP2 (select the gene name)
Genetic variants : HAPMAP27111
Genomic Variants (DGV)SDCBP2 [DGVbeta]
DECIPHERSDCBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSDCBP2 
Mutations
ICGC Data PortalSDCBP2 
TCGA Data PortalSDCBP2 
Broad Tumor PortalSDCBP2
OASIS PortalSDCBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSDCBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSDCBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SDCBP2
DgiDB (Drug Gene Interaction Database)SDCBP2
DoCM (Curated mutations)SDCBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SDCBP2 (select a term)
intoGenSDCBP2
Cancer3DSDCBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617358   
Orphanet
MedgenSDCBP2
Genetic Testing Registry SDCBP2
NextProtQ9H190 [Medical]
TSGene27111
GENETestsSDCBP2
Target ValidationSDCBP2
Huge Navigator SDCBP2 [HugePedia]
snp3D : Map Gene to Disease27111
BioCentury BCIQSDCBP2
ClinGenSDCBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27111
Chemical/Pharm GKB GenePA38033
Clinical trialSDCBP2
Miscellaneous
canSAR (ICR)SDCBP2 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSDCBP2
EVEXSDCBP2
GoPubMedSDCBP2
iHOPSDCBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:40:10 CEST 2017

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