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SDHAF4 (succinate dehydrogenase complex assembly factor 4)

Identity

Alias_namesC6orf57
chromosome 6 open reading frame 57
Alias_symbol (synonym)Sdh8
Other alias
HGNC (Hugo) SDHAF4
LocusID (NCBI) 135154
Atlas_Id 77406
Location 6q13  [Link to chromosome band 6q13]
Location_base_pair Starts at 70566922 and ends at 70588903 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTIF (18q21.1) / SDHAF4 (6q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;18)(q13;q21) CTIF/SDHAF4


External links

Nomenclature
HGNC (Hugo)SDHAF4   20957
Cards
Entrez_Gene (NCBI)SDHAF4  135154  succinate dehydrogenase complex assembly factor 4
AliasesC6orf57; Sdh8
GeneCards (Weizmann)SDHAF4
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr6:70566922-70588903 [Contig_View]  SDHAF4 [Vega]
TCGA cBioPortalSDHAF4
AceView (NCBI)SDHAF4
Genatlas (Paris)SDHAF4
WikiGenes135154
SOURCE (Princeton)SDHAF4
Genetics Home Reference (NIH)SDHAF4
Genomic and cartography
GoldenPath hg38 (UCSC)SDHAF4  -     chr6:70566922-70588903 +  6q13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SDHAF4  -     6q13   [Description]    (hg19-Feb_2009)
EnsemblSDHAF4 - 6q13 [CytoView hg19]  SDHAF4 - 6q13 [CytoView hg38]
Mapping of homologs : NCBISDHAF4 [Mapview hg19]  SDHAF4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC018085 BC104649 BG703280 CF597237 GQ129294
RefSeq transcript (Entrez)NM_145267
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SDHAF4
Cluster EST : UnigeneHs.418495 [ NCBI ]
CGAP (NCI)Hs.418495
Gene ExpressionSDHAF4 [ NCBI-GEO ]   SDHAF4 [ EBI - ARRAY_EXPRESS ]   SDHAF4 [ SEEK ]   SDHAF4 [ MEM ]
Gene Expression Viewer (FireBrowse)SDHAF4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)135154
GTEX Portal (Tissue expression)SDHAF4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VUM1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VUM1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VUM1
Splice isoforms : SwissVarQ5VUM1
PhosPhoSitePlusQ5VUM1
Domains : Interpro (EBI)DUF1674   
Domain families : Pfam (Sanger)DUF1674 (PF07896)   
Domain families : Pfam (NCBI)pfam07896   
Conserved Domain (NCBI)SDHAF4
DMDM Disease mutations135154
Blocks (Seattle)SDHAF4
SuperfamilyQ5VUM1
Peptide AtlasQ5VUM1
HPRD12888
IPIIPI00103105   
Protein Interaction databases
DIP (DOE-UCLA)Q5VUM1
IntAct (EBI)Q5VUM1
BioGRIDSDHAF4
STRING (EMBL)SDHAF4
ZODIACSDHAF4
Ontologies - Pathways
QuickGOQ5VUM1
Ontology : AmiGOmitochondrial matrix  innate immune response  
Ontology : EGO-EBImitochondrial matrix  innate immune response  
NDEx NetworkSDHAF4
Atlas of Cancer Signalling NetworkSDHAF4
Wikipedia pathwaysSDHAF4
Orthology - Evolution
OrthoDB135154
Phylogenetic Trees/Animal Genes : TreeFamSDHAF4
HOVERGENQ5VUM1
HOGENOMQ5VUM1
Homologs : HomoloGeneSDHAF4
Homology/Alignments : Family Browser (UCSC)SDHAF4
Gene fusions - Rearrangements
Fusion : QuiverSDHAF4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSDHAF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SDHAF4
dbVarSDHAF4
ClinVarSDHAF4
1000_GenomesSDHAF4 
Exome Variant ServerSDHAF4
Varsome BrowserSDHAF4
Genetic variants : HAPMAP135154
Genomic Variants (DGV)SDHAF4 [DGVbeta]
DECIPHERSDHAF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSDHAF4 
Mutations
ICGC Data PortalSDHAF4 
TCGA Data PortalSDHAF4 
Broad Tumor PortalSDHAF4
OASIS PortalSDHAF4 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSDHAF4
BioMutasearch SDHAF4
DgiDB (Drug Gene Interaction Database)SDHAF4
DoCM (Curated mutations)SDHAF4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SDHAF4 (select a term)
intoGenSDHAF4
Cancer3DSDHAF4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSDHAF4
MedgenSDHAF4
Genetic Testing Registry SDHAF4
NextProtQ5VUM1 [Medical]
TSGene135154
GENETestsSDHAF4
Target ValidationSDHAF4
Huge Navigator SDHAF4 [HugePedia]
snp3D : Map Gene to Disease135154
BioCentury BCIQSDHAF4
ClinGenSDHAF4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD135154
Chemical/Pharm GKB GenePA134932684
Clinical trialSDHAF4
Miscellaneous
canSAR (ICR)SDHAF4 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSDHAF4
EVEXSDHAF4
GoPubMedSDHAF4
iHOPSDHAF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:28:23 CEST 2018

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