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SDK1 (sidekick cell adhesion molecule 1)

Identity

Alias_namessidekick homolog 1 (chicken)
sidekick homolog 1, cell adhesion molecule (chicken)
Alias_symbol (synonym)FLJ31425
Other alias-
HGNC (Hugo) SDK1
LocusID (NCBI) 221935
Atlas_Id 54605
Location 7p22.2  [Link to chromosome band 7p22]
Location_base_pair Starts at 4129685 and ends at 4268999 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DPY19L1 (7p14.3) / SDK1 (7p22.2)GRB10 (7p12.1) / SDK1 (7p22.2)MICALL2 (7p22.3) / SDK1 (7p22.2)
PRKCA (17q24.2) / SDK1 (7p22.2)SDK1 (7p22.2) / AMACR (5p13.2)SDK1 (7p22.2) / CHST12 (7p22.3)
SDK1 (7p22.2) / SDK1 (7p22.2)SDK1 (7p22.2) / SETD1A (16p11.2)SDK1 (7p22.2) / XIST (Xq13.2)
VPS41 (7p14.1) / SDK1 (7p22.2)DPY19L1 7p14.3 / SDK1 7p22.2MICALL2 7p22.3 / SDK1 7p22.2
PRKCA 17q24.2 / SDK1 7p22.2SDK1 7p22.2 / CHST12 7p22.3VPS41 7p14.1 / SDK1 7p22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SDK1   19307
Cards
Entrez_Gene (NCBI)SDK1  221935  sidekick cell adhesion molecule 1
Aliases
GeneCards (Weizmann)SDK1
Ensembl hg19 (Hinxton)ENSG00000146555 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146555 [Gene_View]  chr7:4129685-4268999 [Contig_View]  SDK1 [Vega]
ICGC DataPortalENSG00000146555
TCGA cBioPortalSDK1
AceView (NCBI)SDK1
Genatlas (Paris)SDK1
WikiGenes221935
SOURCE (Princeton)SDK1
Genetics Home Reference (NIH)SDK1
Genomic and cartography
GoldenPath hg38 (UCSC)SDK1  -     chr7:4129685-4268999 +  7p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SDK1  -     7p22.2   [Description]    (hg19-Feb_2009)
EnsemblSDK1 - 7p22.2 [CytoView hg19]  SDK1 - 7p22.2 [CytoView hg38]
Mapping of homologs : NCBISDK1 [Mapview hg19]  SDK1 [Mapview hg38]
OMIM607216   
Gene and transcription
Genbank (Entrez)AF131799 AK055987 AK055988 AK074077 AK074083
RefSeq transcript (Entrez)NM_001079653 NM_152744
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SDK1
Cluster EST : UnigeneHs.653013 [ NCBI ]
CGAP (NCI)Hs.653013
Alternative Splicing GalleryENSG00000146555
Gene ExpressionSDK1 [ NCBI-GEO ]   SDK1 [ EBI - ARRAY_EXPRESS ]   SDK1 [ SEEK ]   SDK1 [ MEM ]
Gene Expression Viewer (FireBrowse)SDK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221935
GTEX Portal (Tissue expression)SDK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z5N4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z5N4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z5N4
Splice isoforms : SwissVarQ7Z5N4
PhosPhoSitePlusQ7Z5N4
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)FN3_dom    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2   
Domain families : Pfam (Sanger)fn3 (PF00041)    I-set (PF07679)   
Domain families : Pfam (NCBI)pfam00041    pfam07679   
Domain families : Smart (EMBL)FN3 (SM00060)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)SDK1
DMDM Disease mutations221935
Blocks (Seattle)SDK1
SuperfamilyQ7Z5N4
Human Protein AtlasENSG00000146555
Peptide AtlasQ7Z5N4
HPRD07388
IPIIPI00784490   IPI00942650   IPI01014396   IPI01026120   IPI00894181   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z5N4
IntAct (EBI)Q7Z5N4
FunCoupENSG00000146555
BioGRIDSDK1
STRING (EMBL)SDK1
ZODIACSDK1
Ontologies - Pathways
QuickGOQ7Z5N4
Ontology : AmiGOplasma membrane  homophilic cell adhesion via plasma membrane adhesion molecules  synapse assembly  retina layer formation  integral component of membrane  cell junction  identical protein binding  synapse  behavioral response to cocaine  regulation of dendritic spine development  extracellular exosome  
Ontology : EGO-EBIplasma membrane  homophilic cell adhesion via plasma membrane adhesion molecules  synapse assembly  retina layer formation  integral component of membrane  cell junction  identical protein binding  synapse  behavioral response to cocaine  regulation of dendritic spine development  extracellular exosome  
NDEx NetworkSDK1
Atlas of Cancer Signalling NetworkSDK1
Wikipedia pathwaysSDK1
Orthology - Evolution
OrthoDB221935
GeneTree (enSembl)ENSG00000146555
Phylogenetic Trees/Animal Genes : TreeFamSDK1
HOVERGENQ7Z5N4
HOGENOMQ7Z5N4
Homologs : HomoloGeneSDK1
Homology/Alignments : Family Browser (UCSC)SDK1
Gene fusions - Rearrangements
Fusion : MitelmanDPY19L1/SDK1 [7p14.3/7p22.2]  [t(7;7)(p14;p22)]  
Fusion : MitelmanGRB10/SDK1 [7p12.1/7p22.2]  [t(7;7)(p12;p22)]  
Fusion : MitelmanMICALL2/SDK1 [7p22.3/7p22.2]  [t(7;7)(p22;p22)]  
Fusion : MitelmanPRKCA/SDK1 [17q24.2/7p22.2]  [t(7;17)(p22;q24)]  
Fusion : MitelmanSDK1/AMACR [7p22.2/5p13.2]  [t(5;7)(p13;p22)]  
Fusion : MitelmanSDK1/CHST12 [7p22.2/7p22.3]  [t(7;7)(p22;p22)]  
Fusion : MitelmanVPS41/SDK1 [7p14.1/7p22.2]  [t(7;7)(p14;p22)]  
Fusion: TCGADPY19L1 7p14.3 SDK1 7p22.2 HNSC
Fusion: TCGAMICALL2 7p22.3 SDK1 7p22.2 LUAD
Fusion: TCGAPRKCA 17q24.2 SDK1 7p22.2 LUSC
Fusion: TCGASDK1 7p22.2 CHST12 7p22.3 PRAD
Fusion: TCGAVPS41 7p14.1 SDK1 7p22.2 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSDK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SDK1
dbVarSDK1
ClinVarSDK1
1000_GenomesSDK1 
Exome Variant ServerSDK1
ExAC (Exome Aggregation Consortium)SDK1 (select the gene name)
Genetic variants : HAPMAP221935
Genomic Variants (DGV)SDK1 [DGVbeta]
DECIPHERSDK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSDK1 
Mutations
ICGC Data PortalSDK1 
TCGA Data PortalSDK1 
Broad Tumor PortalSDK1
OASIS PortalSDK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSDK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSDK1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SDK1
DgiDB (Drug Gene Interaction Database)SDK1
DoCM (Curated mutations)SDK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SDK1 (select a term)
intoGenSDK1
Cancer3DSDK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607216   
Orphanet
MedgenSDK1
Genetic Testing Registry SDK1
NextProtQ7Z5N4 [Medical]
TSGene221935
GENETestsSDK1
Target ValidationSDK1
Huge Navigator SDK1 [HugePedia]
snp3D : Map Gene to Disease221935
BioCentury BCIQSDK1
ClinGenSDK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221935
Chemical/Pharm GKB GenePA134957188
Clinical trialSDK1
Miscellaneous
canSAR (ICR)SDK1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSDK1
EVEXSDK1
GoPubMedSDK1
iHOPSDK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:30:17 CEST 2017

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