SDR16C5 (short chain dehydrogenase/reductase family 16C member 5)

2016-10-01  

Identity

HGNC
LOCATION
8q12.1
LOCUSID
ALIAS
EPHD-2,RDH#2,RDH-E2,RDHE2,retSDR2
FUSION GENES

Other Information

Locus ID:

NCBI: 195814
MIM: 608989
HGNC: 30311
Ensembl: ENSG00000170786

Variants:

dbSNP: 195814
ClinVar: 195814
TCGA: ENSG00000170786
COSMIC: SDR16C5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170786ENST00000303749Q8N3Y7
ENSG00000170786ENST00000396721Q8N3Y7
ENSG00000170786ENST00000522671G3V145

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Retinol metabolismKEGGko00830
Retinol metabolismKEGGhsa00830
Signal TransductionREACTOMER-HSA-162582
Signaling by Retinoic AcidREACTOMER-HSA-5362517
RA biosynthesis pathwayREACTOMER-HSA-5365859

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
205466122010The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.19
123724102002Identification of the hRDH-E2 gene, a novel member of the SDR family, and its increased expression in psoriatic lesion.7
154573462004hRDH-E2 gene polymorphisms, variable transcriptional start sites, and psoriasis.3

Citation

Dessen P

SDR16C5 (short chain dehydrogenase/reductase family 16C member 5)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56294/sdr16c5