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SDSL (serine dehydratase like)

Identity

Alias_namesserine dehydratase-like
Alias_symbol (synonym)SDS-RS1
cSDH
Other aliasSDH 2
TDH
HGNC (Hugo) SDSL
LocusID (NCBI) 113675
Atlas_Id 73076
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 113422390 and ends at 113438276 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SDSL (12q24.13) / MBOAT7 (19q13.42)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SDSL   30404
Cards
Entrez_Gene (NCBI)SDSL  113675  serine dehydratase like
AliasesSDH; SDS-RS1; TDH; cSDH
GeneCards (Weizmann)SDSL
Ensembl hg19 (Hinxton)ENSG00000139410 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139410 [Gene_View]  chr12:113422390-113438276 [Contig_View]  SDSL [Vega]
ICGC DataPortalENSG00000139410
TCGA cBioPortalSDSL
AceView (NCBI)SDSL
Genatlas (Paris)SDSL
WikiGenes113675
SOURCE (Princeton)SDSL
Genetics Home Reference (NIH)SDSL
Genomic and cartography
GoldenPath hg38 (UCSC)SDSL  -     chr12:113422390-113438276 +  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SDSL  -     12q24.13   [Description]    (hg19-Feb_2009)
EnsemblSDSL - 12q24.13 [CytoView hg19]  SDSL - 12q24.13 [CytoView hg38]
Mapping of homologs : NCBISDSL [Mapview hg19]  SDSL [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF134473 BC009849 BC091479 DQ893143 DQ896429
RefSeq transcript (Entrez)NM_001304993 NM_138432
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SDSL
Cluster EST : UnigeneHs.337594 [ NCBI ]
CGAP (NCI)Hs.337594
Alternative Splicing GalleryENSG00000139410
Gene ExpressionSDSL [ NCBI-GEO ]   SDSL [ EBI - ARRAY_EXPRESS ]   SDSL [ SEEK ]   SDSL [ MEM ]
Gene Expression Viewer (FireBrowse)SDSL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)113675
GTEX Portal (Tissue expression)SDSL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GA7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GA7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GA7
Splice isoforms : SwissVarQ96GA7
Catalytic activity : Enzyme4.3.1.19 [ Enzyme-Expasy ]   4.3.1.194.3.1.19 [ IntEnz-EBI ]   4.3.1.19 [ BRENDA ]   4.3.1.19 [ KEGG ]   
PhosPhoSitePlusQ96GA7
Domaine pattern : Prosite (Expaxy)DEHYDRATASE_SER_THR (PS00165)   
Domains : Interpro (EBI)Ser/Thr_deHydtase_PyrdxlP-BS    TrpB-like_PLP-dep   
Domain families : Pfam (Sanger)PALP (PF00291)   
Domain families : Pfam (NCBI)pfam00291   
Conserved Domain (NCBI)SDSL
DMDM Disease mutations113675
Blocks (Seattle)SDSL
PDB (SRS)2RKB   
PDB (PDBSum)2RKB   
PDB (IMB)2RKB   
PDB (RSDB)2RKB   
Structural Biology KnowledgeBase2RKB   
SCOP (Structural Classification of Proteins)2RKB   
CATH (Classification of proteins structures)2RKB   
SuperfamilyQ96GA7
Human Protein AtlasENSG00000139410
Peptide AtlasQ96GA7
HPRD11542
IPIIPI00062419   IPI01021655   IPI01022375   IPI01021269   IPI01021183   
Protein Interaction databases
DIP (DOE-UCLA)Q96GA7
IntAct (EBI)Q96GA7
FunCoupENSG00000139410
BioGRIDSDSL
STRING (EMBL)SDSL
ZODIACSDSL
Ontologies - Pathways
QuickGOQ96GA7
Ontology : AmiGOmolecular_function  L-serine ammonia-lyase activity  L-threonine ammonia-lyase activity  mitochondrion  cellular amino acid metabolic process  biological_process  pyridoxal phosphate binding  identical protein binding  extracellular exosome  
Ontology : EGO-EBImolecular_function  L-serine ammonia-lyase activity  L-threonine ammonia-lyase activity  mitochondrion  cellular amino acid metabolic process  biological_process  pyridoxal phosphate binding  identical protein binding  extracellular exosome  
Pathways : KEGGGlycine, serine and threonine metabolism    Cysteine and methionine metabolism    Valine, leucine and isoleucine biosynthesis   
NDEx NetworkSDSL
Atlas of Cancer Signalling NetworkSDSL
Wikipedia pathwaysSDSL
Orthology - Evolution
OrthoDB113675
GeneTree (enSembl)ENSG00000139410
Phylogenetic Trees/Animal Genes : TreeFamSDSL
HOVERGENQ96GA7
HOGENOMQ96GA7
Homologs : HomoloGeneSDSL
Homology/Alignments : Family Browser (UCSC)SDSL
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSDSL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SDSL
dbVarSDSL
ClinVarSDSL
1000_GenomesSDSL 
Exome Variant ServerSDSL
ExAC (Exome Aggregation Consortium)SDSL (select the gene name)
Genetic variants : HAPMAP113675
Genomic Variants (DGV)SDSL [DGVbeta]
DECIPHERSDSL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSDSL 
Mutations
ICGC Data PortalSDSL 
TCGA Data PortalSDSL 
Broad Tumor PortalSDSL
OASIS PortalSDSL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSDSL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSDSL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SDSL
DgiDB (Drug Gene Interaction Database)SDSL
DoCM (Curated mutations)SDSL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SDSL (select a term)
intoGenSDSL
Cancer3DSDSL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSDSL
Genetic Testing Registry SDSL
NextProtQ96GA7 [Medical]
TSGene113675
GENETestsSDSL
Target ValidationSDSL
Huge Navigator SDSL [HugePedia]
snp3D : Map Gene to Disease113675
BioCentury BCIQSDSL
ClinGenSDSL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD113675
Chemical/Pharm GKB GenePA134862016
Clinical trialSDSL
Miscellaneous
canSAR (ICR)SDSL (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSDSL
EVEXSDSL
GoPubMedSDSL
iHOPSDSL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:37:26 CEST 2017

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