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SDSL (serine dehydratase like)

Identity

Alias (NCBI)SDH 2
SDS-RS1
TDH
cSDH
HGNC (Hugo) SDSL
HGNC Alias symbSDS-RS1
cSDH
HGNC Previous nameserine dehydratase-like
LocusID (NCBI) 113675
Atlas_Id 73076
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 113422390 and ends at 113438276 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SDSL (12q24.13) / MBOAT7 (19q13.42)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SDSL   30404
Cards
Entrez_Gene (NCBI)SDSL    serine dehydratase like
AliasesSDH; SDS-RS1; TDH; cSDH
GeneCards (Weizmann)SDSL
Ensembl hg19 (Hinxton)ENSG00000139410 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139410 [Gene_View]  ENSG00000139410 [Sequence]  chr12:113422390-113438276 [Contig_View]  SDSL [Vega]
ICGC DataPortalENSG00000139410
TCGA cBioPortalSDSL
AceView (NCBI)SDSL
Genatlas (Paris)SDSL
SOURCE (Princeton)SDSL
Genetics Home Reference (NIH)SDSL
Genomic and cartography
GoldenPath hg38 (UCSC)SDSL  -     chr12:113422390-113438276 +  12q24.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SDSL  -     12q24.13   [Description]    (hg19-Feb_2009)
GoldenPathSDSL - 12q24.13 [CytoView hg19]  SDSL - 12q24.13 [CytoView hg38]
ImmunoBaseENSG00000139410
Genome Data Viewer NCBISDSL [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AF134473 BC009849 BC091479
RefSeq transcript (Entrez)NM_001304993 NM_138432
Consensus coding sequences : CCDS (NCBI)SDSL
Gene ExpressionSDSL [ NCBI-GEO ]   SDSL [ EBI - ARRAY_EXPRESS ]   SDSL [ SEEK ]   SDSL [ MEM ]
Gene Expression Viewer (FireBrowse)SDSL [ Firebrowse - Broad ]
GenevisibleExpression of SDSL in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)113675
GTEX Portal (Tissue expression)SDSL
Human Protein AtlasENSG00000139410-SDSL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GA7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GA7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GA7
Catalytic activity : Enzyme4.3.1.19 [ Enzyme-Expasy ]   4.3.1.194.3.1.19 [ IntEnz-EBI ]   4.3.1.19 [ BRENDA ]   4.3.1.19 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ96GA7
Domaine pattern : Prosite (Expaxy)DEHYDRATASE_SER_THR (PS00165)   
Domains : Interpro (EBI)PLP-dep    Ser/Thr_deHydtase_PyrdxlP-BS    Trypto_synt_PLP_dependent   
Domain families : Pfam (Sanger)PALP (PF00291)   
Domain families : Pfam (NCBI)pfam00291   
Conserved Domain (NCBI)SDSL
PDB (RSDB)2RKB   
PDB Europe2RKB   
PDB (PDBSum)2RKB   
PDB (IMB)2RKB   
Structural Biology KnowledgeBase2RKB   
SCOP (Structural Classification of Proteins)2RKB   
CATH (Classification of proteins structures)2RKB   
SuperfamilyQ96GA7
AlphaFold pdb e-kbQ96GA7   
Human Protein Atlas [tissue]ENSG00000139410-SDSL [tissue]
HPRD11542
Protein Interaction databases
DIP (DOE-UCLA)Q96GA7
IntAct (EBI)Q96GA7
BioGRIDSDSL
STRING (EMBL)SDSL
ZODIACSDSL
Ontologies - Pathways
QuickGOQ96GA7
Ontology : AmiGOmolecular_function  L-serine ammonia-lyase activity  L-threonine ammonia-lyase activity  cytosol  threonine catabolic process  biological_process  isoleucine biosynthetic process  L-threonine catabolic process to glycine  pyridoxal phosphate binding  identical protein binding  
Ontology : EGO-EBImolecular_function  L-serine ammonia-lyase activity  L-threonine ammonia-lyase activity  cytosol  threonine catabolic process  biological_process  isoleucine biosynthetic process  L-threonine catabolic process to glycine  pyridoxal phosphate binding  identical protein binding  
NDEx NetworkSDSL
Atlas of Cancer Signalling NetworkSDSL
Wikipedia pathwaysSDSL
Orthology - Evolution
OrthoDB113675
GeneTree (enSembl)ENSG00000139410
Phylogenetic Trees/Animal Genes : TreeFamSDSL
Homologs : HomoloGeneSDSL
Homology/Alignments : Family Browser (UCSC)SDSL
Gene fusions - Rearrangements
Fusion : QuiverSDSL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSDSL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SDSL
dbVarSDSL
ClinVarSDSL
MonarchSDSL
1000_GenomesSDSL 
Exome Variant ServerSDSL
GNOMAD BrowserENSG00000139410
Varsome BrowserSDSL
ACMGSDSL variants
VarityQ96GA7
Genomic Variants (DGV)SDSL [DGVbeta]
DECIPHERSDSL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSDSL 
Mutations
ICGC Data PortalSDSL 
TCGA Data PortalSDSL 
Broad Tumor PortalSDSL
OASIS PortalSDSL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSDSL  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSDSL
Mutations and Diseases : HGMDSDSL
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSDSL
DgiDB (Drug Gene Interaction Database)SDSL
DoCM (Curated mutations)SDSL
CIViC (Clinical Interpretations of Variants in Cancer)SDSL
Cancer3DSDSL
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSDSL
MedgenSDSL
Genetic Testing Registry SDSL
NextProtQ96GA7 [Medical]
GENETestsSDSL
Target ValidationSDSL
Huge Navigator SDSL [HugePedia]
ClinGenSDSL
Clinical trials, drugs, therapy
MyCancerGenomeSDSL
Protein Interactions : CTDSDSL
Pharm GKB GenePA134862016
PharosQ96GA7
Clinical trialSDSL
Miscellaneous
canSAR (ICR)SDSL
HarmonizomeSDSL
DataMed IndexSDSL
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSDSL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:20:06 CEST 2021

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