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SEC11C (SEC11 homolog C, signal peptidase complex subunit)

Identity

Alias_namesSEC11L3
SEC11-like 3 (S. cerevisiae)
SEC11 homolog C (S. cerevisiae)
Alias_symbol (synonym)SPC21
SPCS4C
Other alias
HGNC (Hugo) SEC11C
LocusID (NCBI) 90701
Atlas_Id 73078
Location 18q21.32  [Link to chromosome band 18q21]
Location_base_pair Starts at 59139857 and ends at 59158837 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HARS2 (5q31.3) / SEC11C (18q21.32)SLC25A24 (1p13.3) / SEC11C (18q21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC11C   23400
Cards
Entrez_Gene (NCBI)SEC11C  90701  SEC11 homolog C, signal peptidase complex subunit
AliasesSEC11L3; SPC21; SPCS4C
GeneCards (Weizmann)SEC11C
Ensembl hg19 (Hinxton)ENSG00000166562 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166562 [Gene_View]  chr18:59139857-59158837 [Contig_View]  SEC11C [Vega]
ICGC DataPortalENSG00000166562
TCGA cBioPortalSEC11C
AceView (NCBI)SEC11C
Genatlas (Paris)SEC11C
WikiGenes90701
SOURCE (Princeton)SEC11C
Genetics Home Reference (NIH)SEC11C
Genomic and cartography
GoldenPath hg38 (UCSC)SEC11C  -     chr18:59139857-59158837 +  18q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEC11C  -     18q21.32   [Description]    (hg19-Feb_2009)
EnsemblSEC11C - 18q21.32 [CytoView hg19]  SEC11C - 18q21.32 [CytoView hg38]
Mapping of homologs : NCBISEC11C [Mapview hg19]  SEC11C [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF212233 AK295346 AK307127 AK311213 AK314107
RefSeq transcript (Entrez)NM_001307941 NM_033280
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEC11C
Cluster EST : UnigeneHs.690840 [ NCBI ]
CGAP (NCI)Hs.690840
Alternative Splicing GalleryENSG00000166562
Gene ExpressionSEC11C [ NCBI-GEO ]   SEC11C [ EBI - ARRAY_EXPRESS ]   SEC11C [ SEEK ]   SEC11C [ MEM ]
Gene Expression Viewer (FireBrowse)SEC11C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90701
GTEX Portal (Tissue expression)SEC11C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BY50   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BY50  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BY50
Splice isoforms : SwissVarQ9BY50
Catalytic activity : Enzyme3.4.21.89 [ Enzyme-Expasy ]   3.4.21.893.4.21.89 [ IntEnz-EBI ]   3.4.21.89 [ BRENDA ]   3.4.21.89 [ KEGG ]   
PhosPhoSitePlusQ9BY50
Domaine pattern : Prosite (Expaxy)SPASE_I_1 (PS00501)    SPASE_I_3 (PS00761)   
Domains : Interpro (EBI)Pept_S26A_signal_pept_1_CS    Pept_S26A_signal_pept_1_Ser-AS    Peptidase_S24/S26_b-rbn    Peptidase_S24_S26    Peptidase_S24_S26A/B/C    Peptidase_S26B   
Domain families : Pfam (Sanger)Peptidase_S24 (PF00717)   
Domain families : Pfam (NCBI)pfam00717   
Conserved Domain (NCBI)SEC11C
DMDM Disease mutations90701
Blocks (Seattle)SEC11C
SuperfamilyQ9BY50
Human Protein AtlasENSG00000166562
Peptide AtlasQ9BY50
HPRD15310
IPIIPI00219436   IPI00646627   
Protein Interaction databases
DIP (DOE-UCLA)Q9BY50
IntAct (EBI)Q9BY50
FunCoupENSG00000166562
BioGRIDSEC11C
STRING (EMBL)SEC11C
ZODIACSEC11C
Ontologies - Pathways
QuickGOQ9BY50
Ontology : AmiGOsignal peptidase complex  endoplasmic reticulum membrane  signal peptide processing  peptidase activity  serine-type peptidase activity  integral component of membrane  organelle membrane  
Ontology : EGO-EBIsignal peptidase complex  endoplasmic reticulum membrane  signal peptide processing  peptidase activity  serine-type peptidase activity  integral component of membrane  organelle membrane  
Pathways : KEGGProtein export   
NDEx NetworkSEC11C
Atlas of Cancer Signalling NetworkSEC11C
Wikipedia pathwaysSEC11C
Orthology - Evolution
OrthoDB90701
GeneTree (enSembl)ENSG00000166562
Phylogenetic Trees/Animal Genes : TreeFamSEC11C
HOVERGENQ9BY50
HOGENOMQ9BY50
Homologs : HomoloGeneSEC11C
Homology/Alignments : Family Browser (UCSC)SEC11C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC11C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC11C
dbVarSEC11C
ClinVarSEC11C
1000_GenomesSEC11C 
Exome Variant ServerSEC11C
ExAC (Exome Aggregation Consortium)SEC11C (select the gene name)
Genetic variants : HAPMAP90701
Genomic Variants (DGV)SEC11C [DGVbeta]
DECIPHERSEC11C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEC11C 
Mutations
ICGC Data PortalSEC11C 
TCGA Data PortalSEC11C 
Broad Tumor PortalSEC11C
OASIS PortalSEC11C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC11C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEC11C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEC11C
DgiDB (Drug Gene Interaction Database)SEC11C
DoCM (Curated mutations)SEC11C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC11C (select a term)
intoGenSEC11C
Cancer3DSEC11C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSEC11C
Genetic Testing Registry SEC11C
NextProtQ9BY50 [Medical]
TSGene90701
GENETestsSEC11C
Target ValidationSEC11C
Huge Navigator SEC11C [HugePedia]
snp3D : Map Gene to Disease90701
BioCentury BCIQSEC11C
ClinGenSEC11C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90701
Chemical/Pharm GKB GenePA162402587
Clinical trialSEC11C
Miscellaneous
canSAR (ICR)SEC11C (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC11C
EVEXSEC11C
GoPubMedSEC11C
iHOPSEC11C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:37:26 CEST 2017

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