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SEC14L1 (SEC14 like lipid binding 1)

Identity

Alias_namesSEC14L
SEC14 (S. cerevisiae)-like 1
SEC14-like 1 (S. cerevisiae)
SEC14-like lipid binding 1
Alias_symbol (synonym)PRELID4A
Other alias
HGNC (Hugo) SEC14L1
LocusID (NCBI) 6397
Atlas_Id 53236
Location 17q25.2  [Link to chromosome band 17q25]
Location_base_pair Starts at 75137005 and ends at 75213181 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EEF1A1 (6q13) / SEC14L1 (17q25.2)LYSMD4 (15q26.3) / SEC14L1 (17q25.2)RECQL5 (17q25.1) / SEC14L1 (17q25.2)
SCARNA16 (17q25.2) / SEC14L1 (17q25.2)SEC14L1 (17q25.2) / GALK1 (17q25.1)SEC14L1 (17q25.2) / SEC14L1 (17q25.2)
SEC14L1 (17q25.2) / SPOP (17q21.33)SEPT9 (17q25.2) / SEC14L1 (17q25.2)SLIRP (14q24.3) / SEC14L1 (17q25.2)
ST6GALNAC3 (1p31.1) / SEC14L1 (17q25.2)RECQL5 17q25.1 / SEC14L1 17q25.2SEC14L1 17q25.2 / GALK1 17q25.1
SEC14L1 17q25.2 / SPOP 17q21.33SEPT9 17q25.2 / SEC14L1 17q25.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC14L1   10698
Cards
Entrez_Gene (NCBI)SEC14L1  6397  SEC14 like lipid binding 1
AliasesPRELID4A; SEC14L
GeneCards (Weizmann)SEC14L1
Ensembl hg19 (Hinxton)ENSG00000129657 [Gene_View]  chr17:75137005-75213181 [Contig_View]  SEC14L1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000129657 [Gene_View]  chr17:75137005-75213181 [Contig_View]  SEC14L1 [Vega]
ICGC DataPortalENSG00000129657
TCGA cBioPortalSEC14L1
AceView (NCBI)SEC14L1
Genatlas (Paris)SEC14L1
WikiGenes6397
SOURCE (Princeton)SEC14L1
Genetics Home Reference (NIH)SEC14L1
Genomic and cartography
GoldenPath hg19 (UCSC)SEC14L1  -     chr17:75137005-75213181 +  17q25.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SEC14L1  -     17q25.2   [Description]    (hg38-Dec_2013)
EnsemblSEC14L1 - 17q25.2 [CytoView hg19]  SEC14L1 - 17q25.2 [CytoView hg38]
Mapping of homologs : NCBISEC14L1 [Mapview hg19]  SEC14L1 [Mapview hg38]
OMIM601504   
Gene and transcription
Genbank (Entrez)AB208811 AK094232 AK130317 AK290913 AK293206
RefSeq transcript (Entrez)NM_001039573 NM_001143998 NM_001143999 NM_001144001 NM_001204408 NM_001204410 NM_003003
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)SEC14L1
Cluster EST : UnigeneHs.720923 [ NCBI ]
CGAP (NCI)Hs.720923
Alternative Splicing GalleryENSG00000129657
Gene ExpressionSEC14L1 [ NCBI-GEO ]   SEC14L1 [ EBI - ARRAY_EXPRESS ]   SEC14L1 [ SEEK ]   SEC14L1 [ MEM ]
Gene Expression Viewer (FireBrowse)SEC14L1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6397
GTEX Portal (Tissue expression)SEC14L1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92503   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92503  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92503
Splice isoforms : SwissVarQ92503
PhosPhoSitePlusQ92503
Domaine pattern : Prosite (Expaxy)CRAL_TRIO (PS50191)    GOLD (PS50866)    PRELI_MSF1 (PS50904)   
Domains : Interpro (EBI)CRAL-TRIO_dom    CRAL/TRIO_N_dom    GOLD_dom    PRELI/MSF1_dom   
Domain families : Pfam (Sanger)CRAL_TRIO (PF00650)    CRAL_TRIO_N (PF03765)    PRELI (PF04707)   
Domain families : Pfam (NCBI)pfam00650    pfam03765    pfam04707   
Domain families : Smart (EMBL)CRAL_TRIO_N (SM01100)  SEC14 (SM00516)  
Conserved Domain (NCBI)SEC14L1
DMDM Disease mutations6397
Blocks (Seattle)SEC14L1
SuperfamilyQ92503
Human Protein AtlasENSG00000129657
Peptide AtlasQ92503
HPRD03295
IPIIPI00883790   IPI00021887   IPI00921489   IPI00442739   
Protein Interaction databases
DIP (DOE-UCLA)Q92503
IntAct (EBI)Q92503
FunCoupENSG00000129657
BioGRIDSEC14L1
STRING (EMBL)SEC14L1
ZODIACSEC14L1
Ontologies - Pathways
QuickGOQ92503
Ontology : AmiGOprotein binding  cytoplasm  cytoplasm  Golgi apparatus  choline transport  integral component of membrane  negative regulation of RIG-I signaling pathway  RIG-I binding  innate immune response  molecular function regulator  
Ontology : EGO-EBIprotein binding  cytoplasm  cytoplasm  Golgi apparatus  choline transport  integral component of membrane  negative regulation of RIG-I signaling pathway  RIG-I binding  innate immune response  molecular function regulator  
NDEx NetworkSEC14L1
Atlas of Cancer Signalling NetworkSEC14L1
Wikipedia pathwaysSEC14L1
Orthology - Evolution
OrthoDB6397
GeneTree (enSembl)ENSG00000129657
Phylogenetic Trees/Animal Genes : TreeFamSEC14L1
HOVERGENQ92503
HOGENOMQ92503
Homologs : HomoloGeneSEC14L1
Homology/Alignments : Family Browser (UCSC)SEC14L1
Gene fusions - Rearrangements
Fusion : MitelmanRECQL5/SEC14L1 [17q25.1/17q25.2]  [t(17;17)(q25;q25)]  
Fusion : MitelmanSEC14L1/GALK1 [17q25.2/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanSEC14L1/SPOP [17q25.2/17q21.33]  [t(17;17)(q21;q25)]  
Fusion : MitelmanSEPT9/SEC14L1 [17q25.2/17q25.2]  [t(17;17)(q25;q25)]  
Fusion: TCGARECQL5 17q25.1 SEC14L1 17q25.2 BRCA
Fusion: TCGASEC14L1 17q25.2 GALK1 17q25.1 LUAD
Fusion: TCGASEC14L1 17q25.2 SPOP 17q21.33 LUSC
Fusion: TCGASEPT9 17q25.2 SEC14L1 17q25.2 BRCA OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC14L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC14L1
dbVarSEC14L1
ClinVarSEC14L1
1000_GenomesSEC14L1 
Exome Variant ServerSEC14L1
ExAC (Exome Aggregation Consortium)SEC14L1 (select the gene name)
Genetic variants : HAPMAP6397
Genomic Variants (DGV)SEC14L1 [DGVbeta]
DECIPHER (Syndromes)17:75137005-75213181  ENSG00000129657
CONAN: Copy Number AnalysisSEC14L1 
Mutations
ICGC Data PortalSEC14L1 
TCGA Data PortalSEC14L1 
Broad Tumor PortalSEC14L1
OASIS PortalSEC14L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC14L1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEC14L1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEC14L1
DgiDB (Drug Gene Interaction Database)SEC14L1
DoCM (Curated mutations)SEC14L1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC14L1 (select a term)
intoGenSEC14L1
Cancer3DSEC14L1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601504   
Orphanet
MedgenSEC14L1
Genetic Testing Registry SEC14L1
NextProtQ92503 [Medical]
TSGene6397
GENETestsSEC14L1
Huge Navigator SEC14L1 [HugePedia]
snp3D : Map Gene to Disease6397
BioCentury BCIQSEC14L1
ClinGenSEC14L1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6397
Chemical/Pharm GKB GenePA35621
Clinical trialSEC14L1
Miscellaneous
canSAR (ICR)SEC14L1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC14L1
EVEXSEC14L1
GoPubMedSEC14L1
iHOPSEC14L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:18:38 CEST 2017

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