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SEC14L2 (SEC14 like lipid binding 2)

Identity

Alias_namesC22orf6
SEC14 (S. cerevisiae)-like 2
SEC14-like 2 (S. cerevisiae)
SEC14-like lipid binding 2
Alias_symbol (synonym)TAP
SPF
KIAA1186
KIAA1658
TAP1
Other alias
HGNC (Hugo) SEC14L2
LocusID (NCBI) 23541
Atlas_Id 46542
Location 22q12.2  [Link to chromosome band 22q12]
Location_base_pair Starts at 30792930 and ends at 30821291 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SEC14L2 (22q12.2) / SLPI (20q13.12)SLPI (20q13.12) / SEC14L2 (22q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC14L2   10699
Cards
Entrez_Gene (NCBI)SEC14L2  23541  SEC14 like lipid binding 2
AliasesC22orf6; SPF; TAP; TAP1
GeneCards (Weizmann)SEC14L2
Ensembl hg19 (Hinxton)ENSG00000100003 [Gene_View]  chr22:30792930-30821291 [Contig_View]  SEC14L2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100003 [Gene_View]  chr22:30792930-30821291 [Contig_View]  SEC14L2 [Vega]
ICGC DataPortalENSG00000100003
TCGA cBioPortalSEC14L2
AceView (NCBI)SEC14L2
Genatlas (Paris)SEC14L2
WikiGenes23541
SOURCE (Princeton)SEC14L2
Genetics Home Reference (NIH)SEC14L2
Genomic and cartography
GoldenPath hg19 (UCSC)SEC14L2  -     chr22:30792930-30821291 +  22q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SEC14L2  -     22q12.2   [Description]    (hg38-Dec_2013)
EnsemblSEC14L2 - 22q12.2 [CytoView hg19]  SEC14L2 - 22q12.2 [CytoView hg38]
Mapping of homologs : NCBISEC14L2 [Mapview hg19]  SEC14L2 [Mapview hg38]
OMIM607558   
Gene and transcription
Genbank (Entrez)AA610131 AB033012 AK056163 AK091402 AK092576
RefSeq transcript (Entrez)NM_001204204 NM_001291932 NM_012429 NM_033382
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)SEC14L2
Cluster EST : UnigeneHs.335614 [ NCBI ]
CGAP (NCI)Hs.335614
Alternative Splicing GalleryENSG00000100003
Gene ExpressionSEC14L2 [ NCBI-GEO ]   SEC14L2 [ EBI - ARRAY_EXPRESS ]   SEC14L2 [ SEEK ]   SEC14L2 [ MEM ]
Gene Expression Viewer (FireBrowse)SEC14L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23541
GTEX Portal (Tissue expression)SEC14L2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO76054   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO76054  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO76054
Splice isoforms : SwissVarO76054
PhosPhoSitePlusO76054
Domaine pattern : Prosite (Expaxy)CRAL_TRIO (PS50191)    GOLD (PS50866)   
Domains : Interpro (EBI)CRAL-bd_toc_tran    CRAL-TRIO_dom    CRAL/TRIO_N_dom    GOLD_dom   
Domain families : Pfam (Sanger)CRAL_TRIO (PF00650)    CRAL_TRIO_N (PF03765)   
Domain families : Pfam (NCBI)pfam00650    pfam03765   
Domain families : Smart (EMBL)CRAL_TRIO_N (SM01100)  SEC14 (SM00516)  
Conserved Domain (NCBI)SEC14L2
DMDM Disease mutations23541
Blocks (Seattle)SEC14L2
PDB (SRS)1O6U    1OLM    4OMJ    4OMK   
PDB (PDBSum)1O6U    1OLM    4OMJ    4OMK   
PDB (IMB)1O6U    1OLM    4OMJ    4OMK   
PDB (RSDB)1O6U    1OLM    4OMJ    4OMK   
Structural Biology KnowledgeBase1O6U    1OLM    4OMJ    4OMK   
SCOP (Structural Classification of Proteins)1O6U    1OLM    4OMJ    4OMK   
CATH (Classification of proteins structures)1O6U    1OLM    4OMJ    4OMK   
SuperfamilyO76054
Human Protein AtlasENSG00000100003
Peptide AtlasO76054
HPRD06344
IPIIPI00018314   IPI00428715   IPI00922001   IPI00880099   IPI00472087   IPI00877966   IPI00878703   IPI00878822   IPI00879046   IPI00879410   IPI00879542   
Protein Interaction databases
DIP (DOE-UCLA)O76054
IntAct (EBI)O76054
FunCoupENSG00000100003
BioGRIDSEC14L2
STRING (EMBL)SEC14L2
ZODIACSEC14L2
Ontologies - Pathways
QuickGOO76054
Ontology : AmiGOtransporter activity  phospholipid binding  nucleus  cytoplasm  transcription, DNA-templated  transport  vitamin E binding  integral component of membrane  regulation of cholesterol biosynthetic process  positive regulation of transcription, DNA-templated  extracellular exosome  
Ontology : EGO-EBItransporter activity  phospholipid binding  nucleus  cytoplasm  transcription, DNA-templated  transport  vitamin E binding  integral component of membrane  regulation of cholesterol biosynthetic process  positive regulation of transcription, DNA-templated  extracellular exosome  
NDEx NetworkSEC14L2
Atlas of Cancer Signalling NetworkSEC14L2
Wikipedia pathwaysSEC14L2
Orthology - Evolution
OrthoDB23541
GeneTree (enSembl)ENSG00000100003
Phylogenetic Trees/Animal Genes : TreeFamSEC14L2
HOVERGENO76054
HOGENOMO76054
Homologs : HomoloGeneSEC14L2
Homology/Alignments : Family Browser (UCSC)SEC14L2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC14L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC14L2
dbVarSEC14L2
ClinVarSEC14L2
1000_GenomesSEC14L2 
Exome Variant ServerSEC14L2
ExAC (Exome Aggregation Consortium)SEC14L2 (select the gene name)
Genetic variants : HAPMAP23541
Genomic Variants (DGV)SEC14L2 [DGVbeta]
DECIPHER (Syndromes)22:30792930-30821291  ENSG00000100003
CONAN: Copy Number AnalysisSEC14L2 
Mutations
ICGC Data PortalSEC14L2 
TCGA Data PortalSEC14L2 
Broad Tumor PortalSEC14L2
OASIS PortalSEC14L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC14L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEC14L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEC14L2
DgiDB (Drug Gene Interaction Database)SEC14L2
DoCM (Curated mutations)SEC14L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC14L2 (select a term)
intoGenSEC14L2
Cancer3DSEC14L2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607558   
Orphanet
MedgenSEC14L2
Genetic Testing Registry SEC14L2
NextProtO76054 [Medical]
TSGene23541
GENETestsSEC14L2
Huge Navigator SEC14L2 [HugePedia]
snp3D : Map Gene to Disease23541
BioCentury BCIQSEC14L2
ClinGenSEC14L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23541
Chemical/Pharm GKB GenePA35622
Clinical trialSEC14L2
Miscellaneous
canSAR (ICR)SEC14L2 (select the gene name)
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC14L2
EVEXSEC14L2
GoPubMedSEC14L2
iHOPSEC14L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:26:31 CET 2017

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