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SEC16A (SEC16 homolog A, endoplasmic reticulum export factor)

Identity

Alias_namesKIAA0310
KIAA0310
SEC16 homolog A (S. cerevisiae)
Alias_symbol (synonym)p250
Sec16L
Other aliasSEC16L
HGNC (Hugo) SEC16A
LocusID (NCBI) 9919
Atlas_Id 53044
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 136440096 and ends at 136483759 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAM129B (9q33.3) / SEC16A (9q34.3)INPP5E (9q34.3) / SEC16A (9q34.3)SEC16A (9q34.3) / NOTCH1 (9q34.3)
SEC16A (9q34.3) / ZNF133 (20p11.23)SEC16A 9q34.3 / NOTCH1 9q34.3FAM129B 9q33.3 / SEC16A 9q34.3
INPP5E 9q34.3 / SEC16A 9q34.3SEC16A 9q34.3 / NOTCH1 9q34.3SEC16A 9q34.3 / ZNF133 20p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC16A   29006
Cards
Entrez_Gene (NCBI)SEC16A  9919  SEC16 homolog A, endoplasmic reticulum export factor
AliasesKIAA0310; SEC16L; p250
GeneCards (Weizmann)SEC16A
Ensembl hg19 (Hinxton)ENSG00000148396 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148396 [Gene_View]  chr9:136440096-136483759 [Contig_View]  SEC16A [Vega]
ICGC DataPortalENSG00000148396
TCGA cBioPortalSEC16A
AceView (NCBI)SEC16A
Genatlas (Paris)SEC16A
WikiGenes9919
SOURCE (Princeton)SEC16A
Genetics Home Reference (NIH)SEC16A
Genomic and cartography
GoldenPath hg38 (UCSC)SEC16A  -     chr9:136440096-136483759 -  9q34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEC16A  -     9q34.3   [Description]    (hg19-Feb_2009)
EnsemblSEC16A - 9q34.3 [CytoView hg19]  SEC16A - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBISEC16A [Mapview hg19]  SEC16A [Mapview hg38]
OMIM612854   
Gene and transcription
Genbank (Entrez)AB002308 AB593115 AB621812 AK074565 AK094041
RefSeq transcript (Entrez)NM_001276418 NM_014866
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEC16A
Cluster EST : UnigeneHs.522500 [ NCBI ]
CGAP (NCI)Hs.522500
Alternative Splicing GalleryENSG00000148396
Gene ExpressionSEC16A [ NCBI-GEO ]   SEC16A [ EBI - ARRAY_EXPRESS ]   SEC16A [ SEEK ]   SEC16A [ MEM ]
Gene Expression Viewer (FireBrowse)SEC16A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9919
GTEX Portal (Tissue expression)SEC16A
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15027   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15027  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15027
Splice isoforms : SwissVarO15027
PhosPhoSitePlusO15027
Domains : Interpro (EBI)ACE1_Sec16_Sec31    Sec16    Sec16_CCD   
Domain families : Pfam (Sanger)Sec16 (PF12932)    Sec16_C (PF12931)   
Domain families : Pfam (NCBI)pfam12932    pfam12931   
Conserved Domain (NCBI)SEC16A
DMDM Disease mutations9919
Blocks (Seattle)SEC16A
SuperfamilyO15027
Human Protein AtlasENSG00000148396
Peptide AtlasO15027
IPIIPI00219314   IPI00166487   IPI00896436   IPI00031242   IPI01009380   IPI00872611   IPI00384060   IPI00442777   IPI00641384   IPI00167711   
Protein Interaction databases
DIP (DOE-UCLA)O15027
IntAct (EBI)O15027
FunCoupENSG00000148396
BioGRIDSEC16A
STRING (EMBL)SEC16A
ZODIACSEC16A
Ontologies - Pathways
QuickGOO15027
Ontology : AmiGOGolgi membrane  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi apparatus  cytosol  cytosol  endoplasmic reticulum organization  protein transport  substantia nigra development  COPII vesicle coating  
Ontology : EGO-EBIGolgi membrane  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi apparatus  cytosol  cytosol  endoplasmic reticulum organization  protein transport  substantia nigra development  COPII vesicle coating  
NDEx NetworkSEC16A
Atlas of Cancer Signalling NetworkSEC16A
Wikipedia pathwaysSEC16A
Orthology - Evolution
OrthoDB9919
GeneTree (enSembl)ENSG00000148396
Phylogenetic Trees/Animal Genes : TreeFamSEC16A
HOVERGENO15027
HOGENOMO15027
Homologs : HomoloGeneSEC16A
Homology/Alignments : Family Browser (UCSC)SEC16A
Gene fusions - Rearrangements
Fusion : MitelmanFAM129B/SEC16A [9q33.3/9q34.3]  [t(9;9)(q34;q34)]  
Fusion : MitelmanINPP5E/SEC16A [9q34.3/9q34.3]  [t(9;9)(q34;q34)]  
Fusion : MitelmanSEC16A/NOTCH1 [9q34.3/9q34.3]  [t(9;9)(q34;q34)]  
Fusion : MitelmanSEC16A/ZNF133 [9q34.3/20p11.23]  [t(9;20)(q34;p11)]  
Fusion: TCGAFAM129B 9q33.3 SEC16A 9q34.3 BRCA
Fusion: TCGAINPP5E 9q34.3 SEC16A 9q34.3 LUSC
Fusion: TCGASEC16A 9q34.3 NOTCH1 9q34.3 THCA
Fusion: TCGASEC16A 9q34.3 ZNF133 20p11.23 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC16A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC16A
dbVarSEC16A
ClinVarSEC16A
1000_GenomesSEC16A 
Exome Variant ServerSEC16A
ExAC (Exome Aggregation Consortium)SEC16A (select the gene name)
Genetic variants : HAPMAP9919
Genomic Variants (DGV)SEC16A [DGVbeta]
DECIPHERSEC16A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEC16A 
Mutations
ICGC Data PortalSEC16A 
TCGA Data PortalSEC16A 
Broad Tumor PortalSEC16A
OASIS PortalSEC16A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC16A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEC16A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEC16A
DgiDB (Drug Gene Interaction Database)SEC16A
DoCM (Curated mutations)SEC16A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC16A (select a term)
intoGenSEC16A
Cancer3DSEC16A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612854   
Orphanet
MedgenSEC16A
Genetic Testing Registry SEC16A
NextProtO15027 [Medical]
TSGene9919
GENETestsSEC16A
Target ValidationSEC16A
Huge Navigator SEC16A [HugePedia]
snp3D : Map Gene to Disease9919
BioCentury BCIQSEC16A
ClinGenSEC16A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9919
Chemical/Pharm GKB GenePA162402611
Clinical trialSEC16A
Miscellaneous
canSAR (ICR)SEC16A (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC16A
EVEXSEC16A
GoPubMedSEC16A
iHOPSEC16A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:30:19 CEST 2017

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