Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SEC16B (SEC16 homolog B, endoplasmic reticulum export factor)

Identity

Alias (NCBI)LZTR2
PGPR-p117
RGPR
RGPR-p117
SEC16S
HGNC (Hugo) SEC16B
HGNC Alias symbRGPR
PGPR-p117
Sec16S
HGNC Alias nameregucalcin gene promotor region related protein
HGNC Previous nameLZTR2
HGNC Previous nameleucine zipper transcription regulator 2
 SEC16 homolog B (S. cerevisiae)
LocusID (NCBI) 89866
Atlas_Id 73085
Location 1q25.2  [Link to chromosome band 1q25]
Location_base_pair Starts at 177928788 and ends at 177969922 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SEC16B (1q25.2) / SEC16B (1q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SEC16B   30301
Cards
Entrez_Gene (NCBI)SEC16B    SEC16 homolog B, endoplasmic reticulum export factor
AliasesLZTR2; PGPR-p117; RGPR; RGPR-p117; 
SEC16S
GeneCards (Weizmann)SEC16B
Ensembl hg19 (Hinxton)ENSG00000120341 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120341 [Gene_View]  ENSG00000120341 [Sequence]  chr1:177928788-177969922 [Contig_View]  SEC16B [Vega]
ICGC DataPortalENSG00000120341
TCGA cBioPortalSEC16B
AceView (NCBI)SEC16B
Genatlas (Paris)SEC16B
SOURCE (Princeton)SEC16B
Genetics Home Reference (NIH)SEC16B
Genomic and cartography
GoldenPath hg38 (UCSC)SEC16B  -     chr1:177928788-177969922 -  1q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEC16B  -     1q25.2   [Description]    (hg19-Feb_2009)
GoldenPathSEC16B - 1q25.2 [CytoView hg19]  SEC16B - 1q25.2 [CytoView hg38]
ImmunoBaseENSG00000120341
genome Data Viewer NCBISEC16B [Mapview hg19]  
OMIM612855   
Gene and transcription
Genbank (Entrez)AA086201 AB063357 AK074451 AK090971 AK093939
RefSeq transcript (Entrez)NM_001356499 NM_001356500 NM_033127
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEC16B
Alternative Splicing GalleryENSG00000120341
Gene ExpressionSEC16B [ NCBI-GEO ]   SEC16B [ EBI - ARRAY_EXPRESS ]   SEC16B [ SEEK ]   SEC16B [ MEM ]
Gene Expression Viewer (FireBrowse)SEC16B [ Firebrowse - Broad ]
GenevisibleExpression of SEC16B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89866
GTEX Portal (Tissue expression)SEC16B
Human Protein AtlasENSG00000120341-SEC16B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96JE7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96JE7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96JE7
Splice isoforms : SwissVarQ96JE7
PhosPhoSitePlusQ96JE7
Domains : Interpro (EBI)ACE1_Sec16_Sec31    Sec16    Sec16_CCD   
Domain families : Pfam (Sanger)Sec16 (PF12932)    Sec16_C (PF12931)   
Domain families : Pfam (NCBI)pfam12932    pfam12931   
Conserved Domain (NCBI)SEC16B
Blocks (Seattle)SEC16B
SuperfamilyQ96JE7
Human Protein Atlas [tissue]ENSG00000120341-SEC16B [tissue]
Peptide AtlasQ96JE7
HPRD11491
IPIIPI00896512   IPI00064112   IPI00908680   IPI00168781   IPI00896495   IPI00979965   
Protein Interaction databases
DIP (DOE-UCLA)Q96JE7
IntAct (EBI)Q96JE7
BioGRIDSEC16B
STRING (EMBL)SEC16B
ZODIACSEC16B
Ontologies - Pathways
QuickGOQ96JE7
Ontology : AmiGOGolgi membrane  protein binding  endoplasmic reticulum membrane  cytosol  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  endoplasmic reticulum organization  endoplasmic reticulum organization  Golgi organization  peroxisome organization  positive regulation of gene expression  ER to Golgi transport vesicle membrane  protein transport  peroxisome fission  intracellular membrane-bounded organelle  COPII vesicle coating  COPII vesicle coating  positive regulation of protein exit from endoplasmic reticulum  positive regulation of protein exit from endoplasmic reticulum  endoplasmic reticulum exit site  endoplasmic reticulum exit site  protein localization to endoplasmic reticulum exit site  
Ontology : EGO-EBIGolgi membrane  protein binding  endoplasmic reticulum membrane  cytosol  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  endoplasmic reticulum organization  endoplasmic reticulum organization  Golgi organization  peroxisome organization  positive regulation of gene expression  ER to Golgi transport vesicle membrane  protein transport  peroxisome fission  intracellular membrane-bounded organelle  COPII vesicle coating  COPII vesicle coating  positive regulation of protein exit from endoplasmic reticulum  positive regulation of protein exit from endoplasmic reticulum  endoplasmic reticulum exit site  endoplasmic reticulum exit site  protein localization to endoplasmic reticulum exit site  
NDEx NetworkSEC16B
Atlas of Cancer Signalling NetworkSEC16B
Wikipedia pathwaysSEC16B
Orthology - Evolution
OrthoDB89866
GeneTree (enSembl)ENSG00000120341
Phylogenetic Trees/Animal Genes : TreeFamSEC16B
HOGENOMQ96JE7
Homologs : HomoloGeneSEC16B
Homology/Alignments : Family Browser (UCSC)SEC16B
Gene fusions - Rearrangements
Fusion : QuiverSEC16B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC16B [hg38]
dbVarSEC16B
ClinVarSEC16B
MonarchSEC16B
1000_GenomesSEC16B 
Exome Variant ServerSEC16B
GNOMAD BrowserENSG00000120341
Varsome BrowserSEC16B
Genomic Variants (DGV)SEC16B [DGVbeta]
DECIPHERSEC16B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEC16B 
Mutations
ICGC Data PortalSEC16B 
TCGA Data PortalSEC16B 
Broad Tumor PortalSEC16B
OASIS PortalSEC16B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC16B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSEC16B
Mutations and Diseases : HGMDSEC16B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEC16B
DgiDB (Drug Gene Interaction Database)SEC16B
DoCM (Curated mutations)SEC16B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC16B (select a term)
intoGenSEC16B
Cancer3DSEC16B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612855   
Orphanet
DisGeNETSEC16B
MedgenSEC16B
Genetic Testing Registry SEC16B
NextProtQ96JE7 [Medical]
GENETestsSEC16B
Target ValidationSEC16B
Huge Navigator SEC16B [HugePedia]
ClinGenSEC16B
Clinical trials, drugs, therapy
MyCancerGenomeSEC16B
Protein Interactions : CTD
Pharm GKB GenePA162402680
Clinical trialSEC16B
Miscellaneous
canSAR (ICR)SEC16B (select the gene name)
HarmonizomeSEC16B
DataMed IndexSEC16B
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC16B
EVEXSEC16B
GoPubMedSEC16B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Dec 5 17:26:22 CET 2020
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.