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SEC22B (SEC22 homolog B, vesicle trafficking protein (gene/pseudogene))

Identity

Alias_namesSEC22L1
SEC22, vesicle trafficking protein (S. cerevisiae)-like 1
SEC22 vesicle trafficking protein-like 1 (S. cerevisiae)
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
Alias_symbol (synonym)sec22b
ERS-24
Other alias
HGNC (Hugo) SEC22B
LocusID (NCBI) 9554
Atlas_Id 54607
Location 1q21.1  [Link to chromosome band 1q21]
Location_base_pair Starts at 145096407 and ends at 145116997 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SEC22B (1q21.1) / NOTCH2 (1p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC22B   10700
Cards
Entrez_Gene (NCBI)SEC22B  9554  SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)
AliasesERS-24; SEC22L1
GeneCards (Weizmann)SEC22B
Ensembl hg19 (Hinxton)ENSG00000265808 [Gene_View]  chr1:145096407-145116997 [Contig_View]  SEC22B [Vega]
Ensembl hg38 (Hinxton)ENSG00000265808 [Gene_View]  chr1:145096407-145116997 [Contig_View]  SEC22B [Vega]
ICGC DataPortalENSG00000265808
TCGA cBioPortalSEC22B
AceView (NCBI)SEC22B
Genatlas (Paris)SEC22B
WikiGenes9554
SOURCE (Princeton)SEC22B
Genetics Home Reference (NIH)SEC22B
Genomic and cartography
GoldenPath hg19 (UCSC)SEC22B  -     chr1:145096407-145116997 +  1q21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SEC22B  -     1q21.1   [Description]    (hg38-Dec_2013)
EnsemblSEC22B - 1q21.1 [CytoView hg19]  SEC22B - 1q21.1 [CytoView hg38]
Mapping of homologs : NCBISEC22B [Mapview hg19]  SEC22B [Mapview hg38]
OMIM604029   
Gene and transcription
Genbank (Entrez)AA135767 AF047442 AI085383 AK289875 BC001364
RefSeq transcript (Entrez)NM_004892
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)SEC22B
Cluster EST : UnigeneHs.632438 [ NCBI ]
CGAP (NCI)Hs.632438
Alternative Splicing GalleryENSG00000265808
Gene ExpressionSEC22B [ NCBI-GEO ]   SEC22B [ EBI - ARRAY_EXPRESS ]   SEC22B [ SEEK ]   SEC22B [ MEM ]
Gene Expression Viewer (FireBrowse)SEC22B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9554
GTEX Portal (Tissue expression)SEC22B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75396   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75396  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75396
Splice isoforms : SwissVarO75396
PhosPhoSitePlusO75396
Domaine pattern : Prosite (Expaxy)LONGIN (PS50859)    V_SNARE (PS50892)   
Domains : Interpro (EBI)Longin-like_dom    Longin_dom    Synaptobrevin   
Domain families : Pfam (Sanger)Longin (PF13774)    Synaptobrevin (PF00957)   
Domain families : Pfam (NCBI)pfam13774    pfam00957   
Conserved Domain (NCBI)SEC22B
DMDM Disease mutations9554
Blocks (Seattle)SEC22B
PDB (SRS)2NUP    2NUT    3EGD    3EGX   
PDB (PDBSum)2NUP    2NUT    3EGD    3EGX   
PDB (IMB)2NUP    2NUT    3EGD    3EGX   
PDB (RSDB)2NUP    2NUT    3EGD    3EGX   
Structural Biology KnowledgeBase2NUP    2NUT    3EGD    3EGX   
SCOP (Structural Classification of Proteins)2NUP    2NUT    3EGD    3EGX   
CATH (Classification of proteins structures)2NUP    2NUT    3EGD    3EGX   
SuperfamilyO75396
Human Protein AtlasENSG00000265808
Peptide AtlasO75396
HPRD04939
IPIIPI00006865   
Protein Interaction databases
DIP (DOE-UCLA)O75396
IntAct (EBI)O75396
FunCoupENSG00000265808
BioGRIDSEC22B
STRING (EMBL)SEC22B
ZODIACSEC22B
Ontologies - Pathways
QuickGOO75396
Ontology : AmiGOGolgi membrane  SNARE binding  SNAP receptor activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  exocytosis  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  ER to Golgi transport vesicle membrane  protein transport  integral component of membrane  syntaxin binding  transport vesicle  SNARE complex  regulation of organelle organization  endoplasmic reticulum-Golgi intermediate compartment membrane  melanosome  positive regulation of protein catabolic process  COPII vesicle coating  vesicle fusion with Golgi apparatus  
Ontology : EGO-EBIGolgi membrane  SNARE binding  SNAP receptor activity  protein binding  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  exocytosis  ER to Golgi vesicle-mediated transport  retrograde vesicle-mediated transport, Golgi to ER  ER to Golgi transport vesicle membrane  protein transport  integral component of membrane  syntaxin binding  transport vesicle  SNARE complex  regulation of organelle organization  endoplasmic reticulum-Golgi intermediate compartment membrane  melanosome  positive regulation of protein catabolic process  COPII vesicle coating  vesicle fusion with Golgi apparatus  
Pathways : KEGGSNARE interactions in vesicular transport    Phagosome    Legionellosis   
NDEx NetworkSEC22B
Atlas of Cancer Signalling NetworkSEC22B
Wikipedia pathwaysSEC22B
Orthology - Evolution
OrthoDB9554
GeneTree (enSembl)ENSG00000265808
Phylogenetic Trees/Animal Genes : TreeFamSEC22B
HOVERGENO75396
HOGENOMO75396
Homologs : HomoloGeneSEC22B
Homology/Alignments : Family Browser (UCSC)SEC22B
Gene fusions - Rearrangements
Fusion : MitelmanSEC22B/NOTCH2 [1q21.1/1p12]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC22B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC22B
dbVarSEC22B
ClinVarSEC22B
1000_GenomesSEC22B 
Exome Variant ServerSEC22B
ExAC (Exome Aggregation Consortium)SEC22B (select the gene name)
Genetic variants : HAPMAP9554
Genomic Variants (DGV)SEC22B [DGVbeta]
DECIPHER (Syndromes)1:145096407-145116997  ENSG00000265808
CONAN: Copy Number AnalysisSEC22B 
Mutations
ICGC Data PortalSEC22B 
TCGA Data PortalSEC22B 
Broad Tumor PortalSEC22B
OASIS PortalSEC22B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSEC22B
BioMutasearch SEC22B
DgiDB (Drug Gene Interaction Database)SEC22B
DoCM (Curated mutations)SEC22B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC22B (select a term)
intoGenSEC22B
Cancer3DSEC22B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604029   
Orphanet
MedgenSEC22B
Genetic Testing Registry SEC22B
NextProtO75396 [Medical]
TSGene9554
GENETestsSEC22B
Huge Navigator SEC22B [HugePedia]
snp3D : Map Gene to Disease9554
BioCentury BCIQSEC22B
ClinGenSEC22B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9554
Chemical/Pharm GKB GenePA35623
Clinical trialSEC22B
Miscellaneous
canSAR (ICR)SEC22B (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC22B
EVEXSEC22B
GoPubMedSEC22B
iHOPSEC22B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:26:32 CET 2017

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