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SEC24A (SEC24 homolog A, COPII coat complex component)

Identity

Alias_namesSEC24 (S. cerevisiae) related gene family, member A
SEC24 family, member A (S. cerevisiae)
SEC24 family member A
Other alias-
HGNC (Hugo) SEC24A
LocusID (NCBI) 10802
Atlas_Id 73091
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 134648785 and ends at 134693698 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HFM1 (1p22.2) / SEC24A (5q31.1)RAD17 (5q13.2) / SEC24A (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SEC24A   10703
Cards
Entrez_Gene (NCBI)SEC24A  10802  SEC24 homolog A, COPII coat complex component
Aliases
GeneCards (Weizmann)SEC24A
Ensembl hg19 (Hinxton)ENSG00000113615 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113615 [Gene_View]  chr5:134648785-134693698 [Contig_View]  SEC24A [Vega]
ICGC DataPortalENSG00000113615
TCGA cBioPortalSEC24A
AceView (NCBI)SEC24A
Genatlas (Paris)SEC24A
WikiGenes10802
SOURCE (Princeton)SEC24A
Genetics Home Reference (NIH)SEC24A
Genomic and cartography
GoldenPath hg38 (UCSC)SEC24A  -     chr5:134648785-134693698 +  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEC24A  -     5q31.1   [Description]    (hg19-Feb_2009)
EnsemblSEC24A - 5q31.1 [CytoView hg19]  SEC24A - 5q31.1 [CytoView hg38]
Mapping of homologs : NCBISEC24A [Mapview hg19]  SEC24A [Mapview hg38]
OMIM607183   
Gene and transcription
Genbank (Entrez)AJ131244 AK026545 AK304060 AL080064 AL137677
RefSeq transcript (Entrez)NM_001252231 NM_021982
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SEC24A
Cluster EST : UnigeneHs.595540 [ NCBI ]
CGAP (NCI)Hs.595540
Alternative Splicing GalleryENSG00000113615
Gene ExpressionSEC24A [ NCBI-GEO ]   SEC24A [ EBI - ARRAY_EXPRESS ]   SEC24A [ SEEK ]   SEC24A [ MEM ]
Gene Expression Viewer (FireBrowse)SEC24A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10802
GTEX Portal (Tissue expression)SEC24A
Human Protein AtlasENSG00000113615-SEC24A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95486   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95486  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95486
Splice isoforms : SwissVarO95486
PhosPhoSitePlusO95486
Domains : Interpro (EBI)ADF-H/Gelsolin-like_dom    Gelsolin-like_dom    Sec23/24_helical_dom    Sec23/24_trunk_dom    Sec23_24_beta_S    VWF_A    Znf_Sec23_Sec24   
Domain families : Pfam (Sanger)Gelsolin (PF00626)    Sec23_BS (PF08033)    Sec23_helical (PF04815)    Sec23_trunk (PF04811)    zf-Sec23_Sec24 (PF04810)   
Domain families : Pfam (NCBI)pfam00626    pfam08033    pfam04815    pfam04811    pfam04810   
Conserved Domain (NCBI)SEC24A
DMDM Disease mutations10802
Blocks (Seattle)SEC24A
PDB (SRS)2NUP    2NUT    3EGD    3EGX   
PDB (PDBSum)2NUP    2NUT    3EGD    3EGX   
PDB (IMB)2NUP    2NUT    3EGD    3EGX   
PDB (RSDB)2NUP    2NUT    3EGD    3EGX   
Structural Biology KnowledgeBase2NUP    2NUT    3EGD    3EGX   
SCOP (Structural Classification of Proteins)2NUP    2NUT    3EGD    3EGX   
CATH (Classification of proteins structures)2NUP    2NUT    3EGD    3EGX   
SuperfamilyO95486
Human Protein Atlas [tissue]ENSG00000113615-SEC24A [tissue]
Peptide AtlasO95486
IPIIPI00873472   IPI00178798   IPI00966745   
Protein Interaction databases
DIP (DOE-UCLA)O95486
IntAct (EBI)O95486
FunCoupENSG00000113615
BioGRIDSEC24A
STRING (EMBL)SEC24A
ZODIACSEC24A
Ontologies - Pathways
QuickGOO95486
Ontology : AmiGOGolgi membrane  antigen processing and presentation of peptide antigen via MHC class I  molecular_function  protein binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  zinc ion binding  ER to Golgi transport vesicle membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPII vesicle coat  regulation of low-density lipoprotein particle receptor biosynthetic process  COPII vesicle coating  perinuclear region of cytoplasm  positive regulation of protein secretion  positive regulation of cholesterol homeostasis  
Ontology : EGO-EBIGolgi membrane  antigen processing and presentation of peptide antigen via MHC class I  molecular_function  protein binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  ER to Golgi vesicle-mediated transport  zinc ion binding  ER to Golgi transport vesicle membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPII vesicle coat  regulation of low-density lipoprotein particle receptor biosynthetic process  COPII vesicle coating  perinuclear region of cytoplasm  positive regulation of protein secretion  positive regulation of cholesterol homeostasis  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkSEC24A
Atlas of Cancer Signalling NetworkSEC24A
Wikipedia pathwaysSEC24A
Orthology - Evolution
OrthoDB10802
GeneTree (enSembl)ENSG00000113615
Phylogenetic Trees/Animal Genes : TreeFamSEC24A
HOVERGENO95486
HOGENOMO95486
Homologs : HomoloGeneSEC24A
Homology/Alignments : Family Browser (UCSC)SEC24A
Gene fusions - Rearrangements
Fusion: Tumor Portal SEC24A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC24A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC24A
dbVarSEC24A
ClinVarSEC24A
1000_GenomesSEC24A 
Exome Variant ServerSEC24A
ExAC (Exome Aggregation Consortium)ENSG00000113615
GNOMAD BrowserENSG00000113615
Genetic variants : HAPMAP10802
Genomic Variants (DGV)SEC24A [DGVbeta]
DECIPHERSEC24A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEC24A 
Mutations
ICGC Data PortalSEC24A 
TCGA Data PortalSEC24A 
Broad Tumor PortalSEC24A
OASIS PortalSEC24A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC24A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSEC24A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SEC24A
DgiDB (Drug Gene Interaction Database)SEC24A
DoCM (Curated mutations)SEC24A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SEC24A (select a term)
intoGenSEC24A
Cancer3DSEC24A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607183   
Orphanet
MedgenSEC24A
Genetic Testing Registry SEC24A
NextProtO95486 [Medical]
TSGene10802
GENETestsSEC24A
Target ValidationSEC24A
Huge Navigator SEC24A [HugePedia]
snp3D : Map Gene to Disease10802
BioCentury BCIQSEC24A
ClinGenSEC24A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10802
Chemical/Pharm GKB GenePA35626
Clinical trialSEC24A
Miscellaneous
canSAR (ICR)SEC24A (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSEC24A
EVEXSEC24A
GoPubMedSEC24A
iHOPSEC24A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:26:40 CET 2017

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