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SEC24A (SEC24 homolog A, COPII coat complex component)

Identity

Alias (NCBI)-
HGNC (Hugo) SEC24A
HGNC Previous nameSEC24 (S. cerevisiae) related gene family, member A
 SEC24 family, member A (S. cerevisiae)
 SEC24 family member A
LocusID (NCBI) 10802
Atlas_Id 73091
Location 5q31.1  [Link to chromosome band 5q31]
Location_base_pair Starts at 134648785 and ends at 134727909 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HFM1 (1p22.2)::SEC24A (5q31.1)RAD17 (5q13.2)::SEC24A (5q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SEC24A   10703
Cards
Entrez_Gene (NCBI)SEC24A    SEC24 homolog A, COPII coat complex component
Aliases
GeneCards (Weizmann)SEC24A
Ensembl hg19 (Hinxton)ENSG00000113615 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113615 [Gene_View]  ENSG00000113615 [Sequence]  chr5:134648785-134727909 [Contig_View]  SEC24A [Vega]
ICGC DataPortalENSG00000113615
TCGA cBioPortalSEC24A
AceView (NCBI)SEC24A
Genatlas (Paris)SEC24A
SOURCE (Princeton)SEC24A
Genetics Home Reference (NIH)SEC24A
Genomic and cartography
GoldenPath hg38 (UCSC)SEC24A  -     chr5:134648785-134727909 +  5q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SEC24A  -     5q31.1   [Description]    (hg19-Feb_2009)
GoldenPathSEC24A - 5q31.1 [CytoView hg19]  SEC24A - 5q31.1 [CytoView hg38]
ImmunoBaseENSG00000113615
Genome Data Viewer NCBISEC24A [Mapview hg19]  
OMIM607183   
Gene and transcription
Genbank (Entrez)AJ131244 AK026545 AK304060 AL080064 AL137677
RefSeq transcript (Entrez)NM_001252231 NM_021982
Consensus coding sequences : CCDS (NCBI)SEC24A
Gene ExpressionSEC24A [ NCBI-GEO ]   SEC24A [ EBI - ARRAY_EXPRESS ]   SEC24A [ SEEK ]   SEC24A [ MEM ]
Gene Expression Viewer (FireBrowse)SEC24A [ Firebrowse - Broad ]
GenevisibleExpression of SEC24A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10802
GTEX Portal (Tissue expression)SEC24A
Human Protein AtlasENSG00000113615-SEC24A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95486   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95486  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95486
PhosPhoSitePlusO95486
Domains : Interpro (EBI)ADF-H/Gelsolin-like_dom_sf    Gelsolin-like_dom    Gelsolin-like_dom_sf    Sec23/24_helical_dom    Sec23/24_helical_dom_sf    Sec23/24_trunk_dom    Sec23_24_beta_S    Sec24-like_trunk_dom    vWFA_dom_sf    Znf_Sec23_Sec24   
Domain families : Pfam (Sanger)Gelsolin (PF00626)    Sec23_BS (PF08033)    Sec23_helical (PF04815)    Sec23_trunk (PF04811)    zf-Sec23_Sec24 (PF04810)   
Domain families : Pfam (NCBI)pfam00626    pfam08033    pfam04815    pfam04811    pfam04810   
Conserved Domain (NCBI)SEC24A
PDB (RSDB)2NUP    2NUT    3EGD    3EGX    5VNE    5VNF    5VNG    5VNH    5VNI    5VNJ    5VNK    5VNL    5VNM    5VNN    5VNO   
PDB Europe2NUP    2NUT    3EGD    3EGX    5VNE    5VNF    5VNG    5VNH    5VNI    5VNJ    5VNK    5VNL    5VNM    5VNN    5VNO   
PDB (PDBSum)2NUP    2NUT    3EGD    3EGX    5VNE    5VNF    5VNG    5VNH    5VNI    5VNJ    5VNK    5VNL    5VNM    5VNN    5VNO   
PDB (IMB)2NUP    2NUT    3EGD    3EGX    5VNE    5VNF    5VNG    5VNH    5VNI    5VNJ    5VNK    5VNL    5VNM    5VNN    5VNO   
Structural Biology KnowledgeBase2NUP    2NUT    3EGD    3EGX    5VNE    5VNF    5VNG    5VNH    5VNI    5VNJ    5VNK    5VNL    5VNM    5VNN    5VNO   
SCOP (Structural Classification of Proteins)2NUP    2NUT    3EGD    3EGX    5VNE    5VNF    5VNG    5VNH    5VNI    5VNJ    5VNK    5VNL    5VNM    5VNN    5VNO   
CATH (Classification of proteins structures)2NUP    2NUT    3EGD    3EGX    5VNE    5VNF    5VNG    5VNH    5VNI    5VNJ    5VNK    5VNL    5VNM    5VNN    5VNO   
SuperfamilyO95486
AlphaFold pdb e-kbO95486   
Human Protein Atlas [tissue]ENSG00000113615-SEC24A [tissue]
Protein Interaction databases
DIP (DOE-UCLA)O95486
IntAct (EBI)O95486
BioGRIDSEC24A
STRING (EMBL)SEC24A
ZODIACSEC24A
Ontologies - Pathways
QuickGOO95486
Ontology : AmiGOSNARE binding  antigen processing and presentation of peptide antigen via MHC class I  protein binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  endoplasmic reticulum to Golgi vesicle-mediated transport  endoplasmic reticulum to Golgi vesicle-mediated transport  zinc ion binding  zinc ion binding  ER to Golgi transport vesicle membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPII vesicle coat  COPII vesicle coat  COPII vesicle coating  endoplasmic reticulum exit site  COPII-coated vesicle cargo loading  COPII-coated vesicle cargo loading  
Ontology : EGO-EBISNARE binding  antigen processing and presentation of peptide antigen via MHC class I  protein binding  endoplasmic reticulum membrane  cytosol  intracellular protein transport  endoplasmic reticulum to Golgi vesicle-mediated transport  endoplasmic reticulum to Golgi vesicle-mediated transport  zinc ion binding  zinc ion binding  ER to Golgi transport vesicle membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  COPII vesicle coat  COPII vesicle coat  COPII vesicle coating  endoplasmic reticulum exit site  COPII-coated vesicle cargo loading  COPII-coated vesicle cargo loading  
NDEx NetworkSEC24A
Atlas of Cancer Signalling NetworkSEC24A
Wikipedia pathwaysSEC24A
Orthology - Evolution
OrthoDB10802
GeneTree (enSembl)ENSG00000113615
Phylogenetic Trees/Animal Genes : TreeFamSEC24A
Homologs : HomoloGeneSEC24A
Homology/Alignments : Family Browser (UCSC)SEC24A
Gene fusions - Rearrangements
Fusion : QuiverSEC24A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSEC24A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SEC24A
dbVarSEC24A
ClinVarSEC24A
MonarchSEC24A
1000_GenomesSEC24A 
Exome Variant ServerSEC24A
GNOMAD BrowserENSG00000113615
Varsome BrowserSEC24A
ACMGSEC24A variants
VarityO95486
Genomic Variants (DGV)SEC24A [DGVbeta]
DECIPHERSEC24A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSEC24A 
Mutations
ICGC Data PortalSEC24A 
TCGA Data PortalSEC24A 
Broad Tumor PortalSEC24A
OASIS PortalSEC24A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSEC24A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSEC24A
Mutations and Diseases : HGMDSEC24A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSEC24A
DgiDB (Drug Gene Interaction Database)SEC24A
DoCM (Curated mutations)SEC24A
CIViC (Clinical Interpretations of Variants in Cancer)SEC24A
Cancer3DSEC24A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607183   
Orphanet
DisGeNETSEC24A
MedgenSEC24A
Genetic Testing Registry SEC24A
NextProtO95486 [Medical]
GENETestsSEC24A
Target ValidationSEC24A
Huge Navigator SEC24A [HugePedia]
ClinGenSEC24A
Clinical trials, drugs, therapy
MyCancerGenomeSEC24A
Protein Interactions : CTDSEC24A
Pharm GKB GenePA35626
PharosO95486
Clinical trialSEC24A
Miscellaneous
canSAR (ICR)SEC24A
HarmonizomeSEC24A
ARCHS4SEC24A
DataMed IndexSEC24A
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSEC24A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 19:23:33 CET 2022

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